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Protein
Submitted name:

Cyclin-dependent kinase 5, regulatory subunit 1 (P35)

Gene

CDK5R1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase 5, regulatory subunit 1 (P35)Imported
Gene namesi
Name:CDK5R1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26311.

PTM / Processingi

Proteomic databases

PaxDbiQ8N619.
PRIDEiQ8N619.

Expressioni

Gene expression databases

GenevisibleiQ8N619. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BLOC1S6Q9UL453EBI-10266998,EBI-465781
KRT40Q6A1623EBI-10266998,EBI-10171697
MTUS2Q5JR593EBI-10266998,EBI-742948
NOTCH2NLQ7Z3S93EBI-10266998,EBI-945833
SIAH1Q8IUQ43EBI-10266998,EBI-747107

Protein-protein interaction databases

IntActiQ8N619. 5 interactions.
STRINGi9606.ENSP00000318486.

Structurei

3D structure databases

ProteinModelPortaliQ8N619.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3932. Eukaryota.
ENOG410YFUI. LUCA.
HOVERGENiHBG050853.
KOiK11716.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR004944. CDK5_activator.
IPR013763. Cyclin-like.
[Graphical view]
PANTHERiPTHR23401. PTHR23401. 1 hit.
PfamiPF03261. CDK5_activator. 1 hit.
[Graphical view]
PIRSFiPIRSF009324. Cdk5_activator. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8N619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTVLSLSPS YRKATLFEDG AATVGHYTAV QNSKNAKDKN LKRHSIISVL
60 70 80 90 100
PWKRIVAVSA KKKNSKKVQP NSSYQNNITH LNNENLKKSL SCANLSTFAQ
110 120 130 140 150
PPPAQPPAPP ASQLSGSQTG GSSSVKKAPH PAVTSAGTPK RVIVQASTSE
160 170 180 190 200
LLRCLGEFLC RRCYRLKHLS PTDPVLWLRS VDRSLLLQGW QDKGFITPAN
210 220 230 240 250
VVFLYMLCRD VISSEVGSDH ELQAVLLTCL YLSYSYMGNE ISYPLKPFLV
260 270 280 290 300
ESCKEAFWDR CLSVINLMSS KMLQINADPH YFTQVFSDLK NESGQEDKKR

LLLGLDR
Length:307
Mass (Da):34,060
Last modified:October 1, 2002 - v1
Checksum:i3BC291C0A2476D29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC030792 mRNA. Translation: AAH30792.1.
RefSeqiNP_003876.1. NM_003885.2.
UniGeneiHs.500015.

Genome annotation databases

GeneIDi8851.
KEGGihsa:8851.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC030792 mRNA. Translation: AAH30792.1.
RefSeqiNP_003876.1. NM_003885.2.
UniGeneiHs.500015.

3D structure databases

ProteinModelPortaliQ8N619.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8N619. 5 interactions.
STRINGi9606.ENSP00000318486.

Proteomic databases

PaxDbiQ8N619.
PRIDEiQ8N619.

Protocols and materials databases

DNASUi8851.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8851.
KEGGihsa:8851.

Organism-specific databases

CTDi8851.
PharmGKBiPA26311.

Phylogenomic databases

eggNOGiKOG3932. Eukaryota.
ENOG410YFUI. LUCA.
HOVERGENiHBG050853.
KOiK11716.

Miscellaneous databases

GenomeRNAii8851.

Gene expression databases

GenevisibleiQ8N619. HS.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR004944. CDK5_activator.
IPR013763. Cyclin-like.
[Graphical view]
PANTHERiPTHR23401. PTHR23401. 1 hit.
PfamiPF03261. CDK5_activator. 1 hit.
[Graphical view]
PIRSFiPIRSF009324. Cdk5_activator. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8N619_HUMAN
AccessioniPrimary (citable) accession number: Q8N619
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.