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Q8N5N4

- CC022_HUMAN

UniProt

Q8N5N4 - CC022_HUMAN

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Protein

Uncharacterized protein C3orf22

Gene

C3orf22

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C3orf22
Gene namesi
Name:C3orf22
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:28534. C3orf22.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672383.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 141141Uncharacterized protein C3orf22PRO_0000234430Add
BLAST

Proteomic databases

PaxDbiQ8N5N4.
PRIDEiQ8N5N4.

Expressioni

Gene expression databases

BgeeiQ8N5N4.
CleanExiHS_C3orf22.
ExpressionAtlasiQ8N5N4. baseline and differential.
GenevestigatoriQ8N5N4.

Organism-specific databases

HPAiHPA059199.

Structurei

3D structure databases

ProteinModelPortaliQ8N5N4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG42364.
GeneTreeiENSGT00390000004778.
HOGENOMiHOG000111360.
HOVERGENiHBG081005.
InParanoidiQ8N5N4.
OMAiCNLWELK.
PhylomeDBiQ8N5N4.
TreeFamiTF338341.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8N5N4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDSSACKKSH QSKKWRIQAQ ENFAKKFPYR LSWLTEPDPE PLQPWEVTND
60 70 80 90 100
SNTVQLPLQK RLVPTRSIPV RGLGAPDFTS PSGSCPAPLP APSPPPLCNL
110 120 130 140
WELKLLSRRF PRQLAFLLST RHTEAACPQT SKAAGLSRGL S
Length:141
Mass (Da):15,686
Last modified:October 1, 2002 - v1
Checksum:iFD27529309C1261A
GO
Isoform 2 (identifier: Q8N5N4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     73-141: LGAPDFTSPS...KAAGLSRGLS → VGVRIKKSMNVTSRTLSQMYTHTGKWAPFH

Note: No experimental confirmation available

Show »
Length:102
Mass (Da):11,864
Checksum:iFB7F22F5CCD187EB
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei73 – 14169LGAPD…SRGLS → VGVRIKKSMNVTSRTLSQMY THTGKWAPFH in isoform 2. 1 PublicationVSP_056902Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK097841 mRNA. Translation: BAG53541.1.
AC024558 Genomic DNA. No translation available.
BC032025 mRNA. Translation: AAH32025.1.
CCDSiCCDS3040.1.
RefSeqiNP_689746.1. NM_152533.1.
XP_005247196.1. XM_005247139.1.
UniGeneiHs.178210.

Genome annotation databases

EnsembliENST00000318225; ENSP00000316644; ENSG00000180697.
GeneIDi152065.
KEGGihsa:152065.
UCSCiuc003ejb.3. human.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK097841 mRNA. Translation: BAG53541.1 .
AC024558 Genomic DNA. No translation available.
BC032025 mRNA. Translation: AAH32025.1 .
CCDSi CCDS3040.1.
RefSeqi NP_689746.1. NM_152533.1.
XP_005247196.1. XM_005247139.1.
UniGenei Hs.178210.

3D structure databases

ProteinModelPortali Q8N5N4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q8N5N4.
PRIDEi Q8N5N4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000318225 ; ENSP00000316644 ; ENSG00000180697 .
GeneIDi 152065.
KEGGi hsa:152065.
UCSCi uc003ejb.3. human.

Organism-specific databases

CTDi 152065.
GeneCardsi GC03M126267.
HGNCi HGNC:28534. C3orf22.
HPAi HPA059199.
neXtProti NX_Q8N5N4.
PharmGKBi PA142672383.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG42364.
GeneTreei ENSGT00390000004778.
HOGENOMi HOG000111360.
HOVERGENi HBG081005.
InParanoidi Q8N5N4.
OMAi CNLWELK.
PhylomeDBi Q8N5N4.
TreeFami TF338341.

Miscellaneous databases

GenomeRNAii 152065.
NextBioi 86865.

Gene expression databases

Bgeei Q8N5N4.
CleanExi HS_C3orf22.
ExpressionAtlasi Q8N5N4. baseline and differential.
Genevestigatori Q8N5N4.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Testis.
  2. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.

Entry informationi

Entry nameiCC022_HUMAN
AccessioniPrimary (citable) accession number: Q8N5N4
Secondary accession number(s): B3KUS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM

External Data

Dasty 3