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Q8N5M4

- TTC9C_HUMAN

UniProt

Q8N5M4 - TTC9C_HUMAN

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Protein

Tetratricopeptide repeat protein 9C

Gene
TTC9C
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 9C
Short name:
TPR repeat protein 9C
Gene namesi
Name:TTC9C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:28432. TTC9C.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670685.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 171171Tetratricopeptide repeat protein 9CPRO_0000294465Add
BLAST

Proteomic databases

MaxQBiQ8N5M4.
PaxDbiQ8N5M4.
PRIDEiQ8N5M4.

PTM databases

PhosphoSiteiQ8N5M4.

Expressioni

Gene expression databases

ArrayExpressiQ8N5M4.
BgeeiQ8N5M4.
CleanExiHS_TTC9C.
GenevestigatoriQ8N5M4.

Organism-specific databases

HPAiHPA055169.

Interactioni

Protein-protein interaction databases

BioGridi129507. 24 interactions.
IntActiQ8N5M4. 4 interactions.
STRINGi9606.ENSP00000325266.

Structurei

3D structure databases

ProteinModelPortaliQ8N5M4.
SMRiQ8N5M4. Positions 12-141.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati8 – 4134TPR 1Add
BLAST
Repeati72 – 10736TPR 2Add
BLAST
Repeati108 – 14134TPR 3Add
BLAST

Sequence similaritiesi

Belongs to the TTC9 family.
Contains 3 TPR repeats.

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiNOG74457.
HOGENOMiHOG000012996.
HOVERGENiHBG062451.
OMAiENMLHTT.
PhylomeDBiQ8N5M4.
TreeFamiTF331917.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR023566. PPIase_FKBP.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF07719. TPR_2. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 3 hits.
[Graphical view]
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N5M4-1 [UniParc]FASTAAdd to Basket

« Hide

MEKRLQEAQL YKEEGNQRYR EGKYRDAVSR YHRALLQLRG LDPSLPSPLP    50
NLGPQGPALT PEQENILHTT QTDCYNNLAA CLLQMEPVNY ERVREYSQKV 100
LERQPDNAKA LYRAGVAFFH LQDYDQARHY LLAAVNRQPK DANVRRYLQL 150
TQSELSSYHR KEKQLYLGMF G 171
Length:171
Mass (Da):20,013
Last modified:October 1, 2002 - v1
Checksum:iA583DFC56CD3346E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF451992 mRNA. Translation: AAP97691.1.
AF451993 mRNA. Translation: AAP97692.1.
BC032123 mRNA. Translation: AAH32123.1.
BC053665 mRNA. Translation: AAH53665.1.
CCDSiCCDS8033.1.
RefSeqiNP_776171.1. NM_173810.3.
XP_005273987.1. XM_005273930.1.
XP_005273988.1. XM_005273931.1.
UniGeneiHs.31704.

Genome annotation databases

EnsembliENST00000316461; ENSP00000325266; ENSG00000162222.
ENST00000532583; ENSP00000434340; ENSG00000162222.
GeneIDi283237.
KEGGihsa:283237.
UCSCiuc001nuy.3. human.

Polymorphism databases

DMDMi74759911.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF451992 mRNA. Translation: AAP97691.1 .
AF451993 mRNA. Translation: AAP97692.1 .
BC032123 mRNA. Translation: AAH32123.1 .
BC053665 mRNA. Translation: AAH53665.1 .
CCDSi CCDS8033.1.
RefSeqi NP_776171.1. NM_173810.3.
XP_005273987.1. XM_005273930.1.
XP_005273988.1. XM_005273931.1.
UniGenei Hs.31704.

3D structure databases

ProteinModelPortali Q8N5M4.
SMRi Q8N5M4. Positions 12-141.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 129507. 24 interactions.
IntActi Q8N5M4. 4 interactions.
STRINGi 9606.ENSP00000325266.

PTM databases

PhosphoSitei Q8N5M4.

Polymorphism databases

DMDMi 74759911.

Proteomic databases

MaxQBi Q8N5M4.
PaxDbi Q8N5M4.
PRIDEi Q8N5M4.

Protocols and materials databases

DNASUi 283237.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000316461 ; ENSP00000325266 ; ENSG00000162222 .
ENST00000532583 ; ENSP00000434340 ; ENSG00000162222 .
GeneIDi 283237.
KEGGi hsa:283237.
UCSCi uc001nuy.3. human.

Organism-specific databases

CTDi 283237.
GeneCardsi GC11P062495.
HGNCi HGNC:28432. TTC9C.
HPAi HPA055169.
neXtProti NX_Q8N5M4.
PharmGKBi PA142670685.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG74457.
HOGENOMi HOG000012996.
HOVERGENi HBG062451.
OMAi ENMLHTT.
PhylomeDBi Q8N5M4.
TreeFami TF331917.

Miscellaneous databases

ChiTaRSi TTC9C. human.
GenomeRNAii 283237.
NextBioi 93756.
PROi Q8N5M4.

Gene expression databases

ArrayExpressi Q8N5M4.
Bgeei Q8N5M4.
CleanExi HS_TTC9C.
Genevestigatori Q8N5M4.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR023566. PPIase_FKBP.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR10516. PTHR10516. 1 hit.
Pfami PF07719. TPR_2. 1 hit.
[Graphical view ]
SMARTi SM00028. TPR. 3 hits.
[Graphical view ]
PROSITEi PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Zan Q., Guo J.H., Yu L.
    Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: B-cell and Eye.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiTTC9C_HUMAN
AccessioniPrimary (citable) accession number: Q8N5M4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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