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Q8N5M4 (TTC9C_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tetratricopeptide repeat protein 9C

Short name=TPR repeat protein 9C
Gene names
Name:TTC9C
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length171 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the TTC9 family.

Contains 3 TPR repeats.

Ontologies

Keywords
   DomainRepeat
TPR repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 171171Tetratricopeptide repeat protein 9C
PRO_0000294465

Regions

Repeat8 – 4134TPR 1
Repeat72 – 10736TPR 2
Repeat108 – 14134TPR 3

Sequences

Sequence LengthMass (Da)Tools
Q8N5M4 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: A583DFC56CD3346E

FASTA17120,013
        10         20         30         40         50         60 
MEKRLQEAQL YKEEGNQRYR EGKYRDAVSR YHRALLQLRG LDPSLPSPLP NLGPQGPALT 

        70         80         90        100        110        120 
PEQENILHTT QTDCYNNLAA CLLQMEPVNY ERVREYSQKV LERQPDNAKA LYRAGVAFFH 

       130        140        150        160        170 
LQDYDQARHY LLAAVNRQPK DANVRRYLQL TQSELSSYHR KEKQLYLGMF G 

« Hide

References

« Hide 'large scale' references
[1]Zan Q., Guo J.H., Yu L.
Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Brain.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: B-cell and Eye.
[3]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF451992 mRNA. Translation: AAP97691.1.
AF451993 mRNA. Translation: AAP97692.1.
BC032123 mRNA. Translation: AAH32123.1.
BC053665 mRNA. Translation: AAH53665.1.
CCDSCCDS8033.1.
RefSeqNP_776171.1. NM_173810.3.
XP_005273987.1. XM_005273930.1.
XP_005273988.1. XM_005273931.1.
UniGeneHs.31704.

3D structure databases

ProteinModelPortalQ8N5M4.
SMRQ8N5M4. Positions 12-141.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid129507. 24 interactions.
IntActQ8N5M4. 4 interactions.
STRING9606.ENSP00000325266.

PTM databases

PhosphoSiteQ8N5M4.

Polymorphism databases

DMDM74759911.

Proteomic databases

MaxQBQ8N5M4.
PaxDbQ8N5M4.
PRIDEQ8N5M4.

Protocols and materials databases

DNASU283237.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000316461; ENSP00000325266; ENSG00000162222.
ENST00000532583; ENSP00000434340; ENSG00000162222.
GeneID283237.
KEGGhsa:283237.
UCSCuc001nuy.3. human.

Organism-specific databases

CTD283237.
GeneCardsGC11P062495.
HGNCHGNC:28432. TTC9C.
HPAHPA055169.
neXtProtNX_Q8N5M4.
PharmGKBPA142670685.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG74457.
HOGENOMHOG000012996.
HOVERGENHBG062451.
OMAENMLHTT.
PhylomeDBQ8N5M4.
TreeFamTF331917.

Gene expression databases

ArrayExpressQ8N5M4.
BgeeQ8N5M4.
CleanExHS_TTC9C.
GenevestigatorQ8N5M4.

Family and domain databases

Gene3D1.25.40.10. 1 hit.
InterProIPR023566. PPIase_FKBP.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERPTHR10516. PTHR10516. 1 hit.
PfamPF07719. TPR_2. 1 hit.
[Graphical view]
SMARTSM00028. TPR. 3 hits.
[Graphical view]
PROSITEPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTTC9C. human.
GenomeRNAi283237.
NextBio93756.
PROQ8N5M4.

Entry information

Entry nameTTC9C_HUMAN
AccessionPrimary (citable) accession number: Q8N5M4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM