Q8N5M4 (TTC9C_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tetratricopeptide repeat protein 9C
Short name=TPR repeat protein 9C

Gene names

Name:

TTC9C

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the TTC9 family. Contains 3 TPR repeats.

Ontologies

Keywords
Domain	Repeat TPR repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Tetratricopeptide repeat protein 9C		PRO_0000294465
Regions
	Repeat	8 – 41	34	TPR 1
	Repeat	72 – 107	36	TPR 2
	Repeat	108 – 141	34	TPR 3

Sequences

	Sequence		Length	Mass (Da)
	Q8N5M4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: A583DFC56CD3346E	FASTA	171	20,013
	10 20 30 40 50 60 MEKRLQEAQL YKEEGNQRYR EGKYRDAVSR YHRALLQLRG LDPSLPSPLP NLGPQGPALT 70 80 90 100 110 120 PEQENILHTT QTDCYNNLAA CLLQMEPVNY ERVREYSQKV LERQPDNAKA LYRAGVAFFH 130 140 150 160 170 LQDYDQARHY LLAAVNRQPK DANVRRYLQL TQSELSSYHR KEKQLYLGMF G

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Zan Q., Guo J.H., Yu L. Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Brain.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: B-cell and Eye.
[3]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF451992 mRNA. Translation: AAP97691.1. AF451993 mRNA. Translation: AAP97692.1. BC032123 mRNA. Translation: AAH32123.1. BC053665 mRNA. Translation: AAH53665.1.
IPI	IPI00175096.
RefSeq	NP_776171.1. NM_173810.3.
UniGene	Hs.31704.
3D structure databases
HSSP	HSSP built from PDB template 2DBA based on UniProtKB Q9H3U1.
ProteinModelPortal	Q8N5M4.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8N5M4. 4 interactions.
STRING	9606.ENSP00000325266.
PTM databases
PhosphoSite	Q8N5M4.
Polymorphism databases
DMDM	74759911.
Proteomic databases
PaxDb	Q8N5M4.
PRIDE	Q8N5M4.
Protocols and materials databases
DNASU	283237.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000316461; ENSP00000325266; ENSG00000162222. ENST00000532583; ENSP00000434340; ENSG00000162222.
GeneID	283237.
KEGG	hsa:283237.
UCSC	uc001nuy.3. human.
Organism-specific databases
CTD	283237.
GeneCards	GC11P062495.
HGNC	HGNC:28432. TTC9C.
neXtProt	NX_Q8N5M4.
PharmGKB	PA142670685.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG74457.
HOGENOM	HOG000012996.
HOVERGEN	HBG062451.
OMA	SSYHQKE.
OrthoDB	EOG4BG8XB.
Gene expression databases
ArrayExpress	Q8N5M4.
Bgee	Q8N5M4.
CleanEx	HS_TTC9C.
Genevestigator	Q8N5M4.
Family and domain databases
Gene3D	1.25.40.10. 1 hit.
InterPro	IPR023566. PPIase_FKBP. IPR013026. TPR-contain_dom. IPR011990. TPR-like_helical. IPR013105. TPR_2. IPR019734. TPR_repeat. [Graphical view]
PANTHER	PTHR10516. PTHR10516. 1 hit.
Pfam	PF07719. TPR_2. 1 hit. [Graphical view]
SMART	SM00028. TPR. 3 hits. [Graphical view]
PROSITE	PS50005. TPR. 2 hits. PS50293. TPR_REGION. 2 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	TTC9C. human.
GenomeRNAi	283237.
NextBio	93756.

Entry information

Entry name

TTC9C_HUMAN

Accession

Primary (citable) accession number: Q8N5M4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 10, 2007
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.