Q8N537 (Q8N537_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LGR4 protein EMBL AAH33039.1

Gene names

Name:

LGR4 EMBL AAH33039.1

Organism

Homo sapiens (Human) EMBL AAH33039.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	927 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Leucine-rich repeat SAAS SAAS000372 Repeat SAAS SAAS000372
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	protein-hormone receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8N537 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: C7B2F0C40E584CE8	FASTA	927	101,677
	10 20 30 40 50 60 MPGPLGLLCF LALGLLGSAG PGGAAPPLCA APCSCDGDRR VDCSGKGLTA VPEGLSAFTQ 70 80 90 100 110 120 ALQLAGNDLS FIHPKALSGL KELKVLTLQN NQLKTVPSEA IRGLSALQSL RLDANHITSV 130 140 150 160 170 180 PEDSFEGLVQ LRHLWLDDNS LTEVPVHHLS NLPTLQALTL ALNKISSIPD FAFTNLSSLV 190 200 210 220 230 240 VLHLHNNKIR SLSQHCFDGL DNLETLDLNY NNLGEFPQAI KALPSLKELG FHSNSISVIP 250 260 270 280 290 300 DGAFDGNPLL RTIHLYDNPL SFVGNSAFHN LSDLHSLVIR GASMVQQFPN LTGTVHLESL 310 320 330 340 350 360 TLTGTKISSI PNNLCQEQKM LRTLDLSYNN IRDLPSFNGC HALEEISLQR NQIYQIKEGT 370 380 390 400 410 420 FQGLISLRIL DLSRNLIHEI HSRAFATLGP ITNLDVSFNE LTSFPTEGLN GLNQLKLVGN 430 440 450 460 470 480 FKLKEALAAK DFVNLRSLSV PYAYQCCAFW GCDSYANLNT EDNSLQDHSV AQEKGTADAA 490 500 510 520 530 540 NVTSTLENEE HSQIIIHCTP STGAFKPCEY LLGSWMIRLT VWFIFLVALF FNLLVILTTF 550 560 570 580 590 600 ASCTSLPSSK LFIGLISVSN LFMGIYTGIL TFLDAVSWGR FAEFGIWWET GSGCKVAGFL 610 620 630 640 650 660 AVFSSESAIF LLMLATVERS LSAKDIMKNG KSNHLKQFRV AALLAFLGAT VAGCFPIFHR 670 680 690 700 710 720 GEYSASPLCL PFPTGETPSL GFTVTLVLLN SLAFLLMAVI YTKLYCNLEK EDLSENSQSS 730 740 750 760 770 780 MIKHVAWLIF TNCIFFCPVA FFSFAPLITA ISISPEIMKS VTLIFFPLPA CLNPVLYVFF 790 800 810 820 830 840 NPKFKEDWKL LKRRVTKKSG SVSVSISSQG GCLEQDFYYD CGMYSHLQGN LTVCDCCESF 850 860 870 880 890 900 LLTKPVSCKH LIKSHSCPAL AVASCQRPEG YWSDCGTQSA HSDYADEEDS FVSDSSDQVQ 910 920 ACGRACFYQS RGFPLVRYAY NLPRVKD

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAH33039.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC033039 mRNA. Translation: AAH33039.1.
IPI	IPI00798136.
UniGene	Hs.502176.
3D structure databases
HSSP	HSSP built from PDB template 1D0B based on UniProtKB P25147.
ProteinModelPortal	Q8N537.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000231829.
HOVERGEN	HBG031675.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR002131. Gphrmn_rcpt. IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. IPR000372. LRR-contain_N. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. PF01462. LRRNT. 1 hit. [Graphical view]
PRINTS	PR00373. GLYCHORMONER. PR00237. GPCRRHODOPSN.
SMART	SM00369. LRR_TYP. 5 hits. SM00013. LRRNT. 1 hit. [Graphical view]
PROSITE	PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. PS51450. LRR. 13 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LGR4. human.

Entry information

Entry name

Q8N537_HUMAN

Accession

Primary (citable) accession number: Q8N537

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.