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Protein
Submitted name:

Similar to collagen, type VI, alpha 3

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Similar to collagen, type VI, alpha 3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26729.

PTM / Processingi

Proteomic databases

PaxDbiQ8N4Z1.
PRIDEiQ8N4Z1.

Expressioni

Gene expression databases

BgeeiQ8N4Z1.
GenevisibleiQ8N4Z1. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000295550.

Structurei

3D structure databases

ProteinModelPortaliQ8N4Z1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini204 – 383180VWFAInterPro annotationAdd
BLAST
Domaini421 – 617197VWFAInterPro annotationAdd
BLAST
Domaini793 – 88795Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini914 – 96451BPTI/Kunitz inhibitorInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 BPTI/Kunitz inhibitor domain.UniRule annotation

Keywords - Domaini

CollagenImported

Phylogenomic databases

eggNOGiKOG3544. Eukaryota.
ENOG41103QR. LUCA.
HOGENOMiHOG000168250.
KOiK06238.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.40.50.410. 2 hits.
4.10.410.10. 1 hit.
InterProiIPR008160. Collagen.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR002223. Kunitz_BPTI.
IPR020901. Prtase_inh_Kunz-CS.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01391. Collagen. 1 hit.
PF00014. Kunitz_BPTI. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF53300. SSF53300. 2 hits.
SSF57362. SSF57362. 1 hit.
PROSITEiPS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS50853. FN3. 1 hit.
PS50234. VWFA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8N4Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GFGRRGPPGA KGNKGGPGQP GFEGEQGTRG AQGPAGPAGP PGLIGEQGIS
60 70 80 90 100
GPRGSGGAAG APGERGRTGP LGRKGEPGEP GPKGGIGNRG PRGETGDDGR
110 120 130 140 150
DGVGSEGRRG KKGERGFPGY PGPKGNPGEP GLNGTTGPKG IRGRRGNSGP
160 170 180 190 200
PGIVGQKGDP GYPGPAGPKG NRGDSIDQCA LIQSIKDKCP CCYGPLECPV
210 220 230 240 250
FPTELAFALD TSEGVNQDTF GRMRDVVLSI VNDLTIAESN CPRGARVAVV
260 270 280 290 300
TYNNEVTTEI RFADSKRKSV LLDKIKNLQV ALTSKQQSLE TAMSFVARNT
310 320 330 340 350
FKRVRNGFLM RKVAVFFSNT PTRASPQLRE AVLKLSDAGI TPLFLTRQED
360 370 380 390 400
RQLINALQIN NTAVGHALVL PAGRDLTDFL ENVLTCHVCL DICNIDPSCG
410 420 430 440 450
FGSWRPSFRD RRAAGSDVDI DMAFILDSAE TTTLFQFNEM KKYIAYLVRQ
460 470 480 490 500
LDMSPDPKAS QHFARVAVVQ HAPSESVDNA SMPPVKVEFS LTDYGSKEKL
510 520 530 540 550
VDFLSRGMTQ LQGTRALGSA IEYTIENVFE SAPNPRDLKI VVLMLTGEVP
560 570 580 590 600
EQQLEEAQRV ILQAKCKGYF FVVLGIGRKV NIKEVYTFAS EPNDVFFKLV
610 620 630 640 650
DKSTELNEEP LMRFGRLLPS FVSSENAFYL SPDIRKQCDW FQGDQPTKNL
660 670 680 690 700
VKFGHKQVNV PNNVTSSPTS NPVTTTKPVT TTKPVTTTTK PVTTTTKPVT
710 720 730 740 750
IINQPSVKPA AAKPAPAKPV AAKPVATKMA TVRPPVAVKP ATAAKPVAAK
760 770 780 790 800
PAAVRPPAAA AAKPVATKPE VPRPQAAKPA ATKPATTKPM VKMSREVQVF
810 820 830 840 850
EITENSAKLH WERAEPPGPY FYDLTVTSAH DQSLVLKQNL TVTDRVIGGL
860 870 880 890 900
LAGQTYHVAV VCYLRSQVRA TYHGSFSTKK SQPPPPQPAR SASSSTINLM
910 920 930 940 950
VSTEPLALTE TDICKLPKDE GTCRDFILKW YYDPNTKSCA RFWYGGCGGN
960 970
ENKFGSQKEC EKVCAPVLAK PGVISVMGT
Length:979
Mass (Da):104,829
Last modified:October 1, 2002 - v1
Checksum:iC2835DFCC7432B67
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC033174 mRNA. Translation: AAH33174.1.
RefSeqiNP_004360.2. NM_004369.3.
NP_476508.2. NM_057167.3.
UniGeneiHs.233240.

Genome annotation databases

GeneIDi1293.
KEGGihsa:1293.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC033174 mRNA. Translation: AAH33174.1.
RefSeqiNP_004360.2. NM_004369.3.
NP_476508.2. NM_057167.3.
UniGeneiHs.233240.

3D structure databases

ProteinModelPortaliQ8N4Z1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000295550.

Proteomic databases

PaxDbiQ8N4Z1.
PRIDEiQ8N4Z1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1293.
KEGGihsa:1293.

Organism-specific databases

CTDi1293.
PharmGKBiPA26729.

Phylogenomic databases

eggNOGiKOG3544. Eukaryota.
ENOG41103QR. LUCA.
HOGENOMiHOG000168250.
KOiK06238.

Miscellaneous databases

GenomeRNAii1293.

Gene expression databases

BgeeiQ8N4Z1.
GenevisibleiQ8N4Z1. HS.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.40.50.410. 2 hits.
4.10.410.10. 1 hit.
InterProiIPR008160. Collagen.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR002223. Kunitz_BPTI.
IPR020901. Prtase_inh_Kunz-CS.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01391. Collagen. 1 hit.
PF00014. Kunitz_BPTI. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF53300. SSF53300. 2 hits.
SSF57362. SSF57362. 1 hit.
PROSITEiPS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS50853. FN3. 1 hit.
PS50234. VWFA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Strausberg R.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ8N4Z1_HUMAN
AccessioniPrimary (citable) accession number: Q8N4Z1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.