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Protein
Submitted name:

Putative uncharacterized protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34200.

PTM / Processingi

Proteomic databases

PaxDbiQ8N4Y1.

Expressioni

Gene expression databases

BgeeiQ8N4Y1.
GenevisibleiQ8N4Y1. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000361120.

Structurei

3D structure databases

ProteinModelPortaliQ8N4Y1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 145145Ras-GEFInterPro annotationAdd
BLAST
Domaini295 – 38288Ras-associatingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains N-terminal Ras-GEF domain.SAAS annotation
Contains Ras-GEF domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG3629. Eukaryota.
ENOG410ZUT5. LUCA.
HOVERGENiHBG005864.
KOiK08732.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000159. RA_dom.
IPR015758. RalGDS.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR23113:SF35. PTHR23113:SF35. 2 hits.
PfamiPF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8N4Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VSRDSFRIFQ KLSEIFSDEN NYSLSRELLI KEGTSKFATL EMNPKRAQKR
60 70 80 90 100
PKETGIIQGT VPYLGTFLTD LVMLDTAMKD YLYGRLINFE KRRKEFEVIA
110 120 130 140 150
QIKLLQSACN NYSIAPDEQF GAWFRAVERL SETESYNLSC ELEPPSESAS
160 170 180 190 200
NTLRTKKNTA IVKRWSDRQA PSTELSTSGS SHSKSCDQLR CGPYLSSGDI
210 220 230 240 250
ADALSVHSAG SSSSDVEEIN ISFVPESPDG QEKKFWESAS QSSPETSGIS
260 270 280 290 300
SASSSTSSSS ASTTPVAATR THKRSVSGLC NSSSALPLYN QQVGDCCIIR
310 320 330 340 350
VSLDVDNGNM YKSILVTSQD KAPAVIRKAM DKHNLEEEEP EDYELLQILS
360 370 380 390 400
DDRKLKIPEN ANVFYAMNST ANYDFVLKKR TFTKGVKVKH GASSTLPRMK
410
QKGLKIAKGI F
Length:411
Mass (Da):45,526
Last modified:October 1, 2002 - v1
Checksum:i114CF1F26F923B79
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC033198 mRNA. Translation: AAH33198.1.
RefSeqiNP_001035827.1. NM_001042368.2.
NP_001258703.1. NM_001271774.1.
NP_001258704.1. NM_001271775.1.
NP_001258705.1. NM_001271776.1.
NP_006257.1. NM_006266.3.
UniGeneiHs.106185.

Genome annotation databases

GeneIDi5900.
KEGGihsa:5900.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC033198 mRNA. Translation: AAH33198.1.
RefSeqiNP_001035827.1. NM_001042368.2.
NP_001258703.1. NM_001271774.1.
NP_001258704.1. NM_001271775.1.
NP_001258705.1. NM_001271776.1.
NP_006257.1. NM_006266.3.
UniGeneiHs.106185.

3D structure databases

ProteinModelPortaliQ8N4Y1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000361120.

Proteomic databases

PaxDbiQ8N4Y1.

Protocols and materials databases

DNASUi5900.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5900.
KEGGihsa:5900.

Organism-specific databases

CTDi5900.
PharmGKBiPA34200.

Phylogenomic databases

eggNOGiKOG3629. Eukaryota.
ENOG410ZUT5. LUCA.
HOVERGENiHBG005864.
KOiK08732.

Miscellaneous databases

GenomeRNAii5900.
NextBioi22950.

Gene expression databases

BgeeiQ8N4Y1.
GenevisibleiQ8N4Y1. HS.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000159. RA_dom.
IPR015758. RalGDS.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR23113:SF35. PTHR23113:SF35. 2 hits.
PfamiPF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
[Graphical view]
SMARTiSM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Strausberg R.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Primary B-CellsImported.

Entry informationi

Entry nameiQ8N4Y1_HUMAN
AccessioniPrimary (citable) accession number: Q8N4Y1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 11, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.