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Protein
Submitted name:

Putative uncharacterized protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34200.

PTM / Processingi

Proteomic databases

PaxDbiQ8N4Y1.

Expressioni

Gene expression databases

BgeeiENSG00000160271.
GenevisibleiQ8N4Y1. HS.

Structurei

3D structure databases

ProteinModelPortaliQ8N4Y1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 145Ras-GEFInterPro annotationAdd BLAST145
Domaini295 – 382Ras-associatingInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG3629. Eukaryota.
ENOG410ZUT5. LUCA.
HOVERGENiHBG005864.
KOiK08732.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiView protein in InterPro
IPR000159. RA_dom.
IPR015758. RalGDS.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR029071. Ubiquitin-rel_dom.
PANTHERiPTHR23113:SF250. PTHR23113:SF250. 1 hit.
PfamiView protein in Pfam
PF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
SMARTiView protein in SMART
SM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8N4Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VSRDSFRIFQ KLSEIFSDEN NYSLSRELLI KEGTSKFATL EMNPKRAQKR
60 70 80 90 100
PKETGIIQGT VPYLGTFLTD LVMLDTAMKD YLYGRLINFE KRRKEFEVIA
110 120 130 140 150
QIKLLQSACN NYSIAPDEQF GAWFRAVERL SETESYNLSC ELEPPSESAS
160 170 180 190 200
NTLRTKKNTA IVKRWSDRQA PSTELSTSGS SHSKSCDQLR CGPYLSSGDI
210 220 230 240 250
ADALSVHSAG SSSSDVEEIN ISFVPESPDG QEKKFWESAS QSSPETSGIS
260 270 280 290 300
SASSSTSSSS ASTTPVAATR THKRSVSGLC NSSSALPLYN QQVGDCCIIR
310 320 330 340 350
VSLDVDNGNM YKSILVTSQD KAPAVIRKAM DKHNLEEEEP EDYELLQILS
360 370 380 390 400
DDRKLKIPEN ANVFYAMNST ANYDFVLKKR TFTKGVKVKH GASSTLPRMK
410
QKGLKIAKGI F
Length:411
Mass (Da):45,526
Last modified:October 1, 2002 - v1
Checksum:i114CF1F26F923B79
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC033198 mRNA. Translation: AAH33198.1.
RefSeqiNP_001035827.1. NM_001042368.2.
NP_001258703.1. NM_001271774.1.
NP_001258704.1. NM_001271775.1.
NP_001258705.1. NM_001271776.1.
NP_006257.1. NM_006266.3.
UniGeneiHs.106185.

Genome annotation databases

GeneIDi5900.
KEGGihsa:5900.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ8N4Y1_HUMAN
AccessioniPrimary (citable) accession number: Q8N4Y1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 5, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.