Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Coiled-coil domain-containing protein 24

Gene

CCDC24

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 24
Gene namesi
Name:CCDC24
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000159214.12
HGNCiHGNC:28688 CCDC24
neXtProtiNX_Q8N4L8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000159214
PharmGKBiPA142672182

Polymorphism and mutation databases

BioMutaiCCDC24
DMDMi74750991

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002336661 – 307Coiled-coil domain-containing protein 24Add BLAST307

Proteomic databases

PaxDbiQ8N4L8
PRIDEiQ8N4L8
ProteomicsDBi71941
71942 [Q8N4L8-2]

Expressioni

Gene expression databases

BgeeiENSG00000159214
CleanExiHS_CCDC24
ExpressionAtlasiQ8N4L8 baseline and differential
GenevisibleiQ8N4L8 HS

Organism-specific databases

HPAiHPA035424
HPA061710

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi127217, 5 interactors
IntActiQ8N4L8, 29 interactors
MINTiQ8N4L8
STRINGi9606.ENSP00000361392

Structurei

3D structure databases

ProteinModelPortaliQ8N4L8
SMRiQ8N4L8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili168 – 225Sequence analysisAdd BLAST58

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IW4J Eukaryota
ENOG41125IY LUCA
GeneTreeiENSGT00390000011926
HOGENOMiHOG000111406
HOVERGENiHBG081038
InParanoidiQ8N4L8
OMAiTCRWGRK
OrthoDBiEOG091G1373
PhylomeDBiQ8N4L8
TreeFamiTF336952

Family and domain databases

InterProiView protein in InterPro
IPR031367 CCDC24
PANTHERiPTHR28601 PTHR28601, 1 hit
PfamiView protein in Pfam
PF15669 CCDC24, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8N4L8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLRHSPSLWE LVEEHVPLRE RREVKRILGE AAVDLSLELR AEVAMLRALL
60 70 80 90 100
QEARSSQAPS SRPISDPSSL LAPPPLLKDL LRQELRQLLQ GLRHKAICEG
110 120 130 140 150
RDQAQAWVQY SPRVLHFALE EPRCDLPEQE IFQMRGGGPS SGHRDLSIIK
160 170 180 190 200
DQLNVSNIDQ VARHLRGLLE EECHTLEREI LILQRCLEEE YLRPCHPSEA
210 220 230 240 250
ALEPTLAELK EQKKAMEQEL QASVGPSCVS PNHRQRPLGS STQGLRPPLP
260 270 280 290 300
LCGVAPLQCC LPAPPLEPYL RPRGQSATHR WGRQLQCSPR EGPASTPMSS

AAPQAPA
Length:307
Mass (Da):34,322
Last modified:October 1, 2002 - v1
Checksum:i55B2AD791E85B1F4
GO
Isoform 2 (identifier: Q8N4L8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     43-78: Missing.

Note: No experimental confirmation available.
Show »
Length:271
Mass (Da):30,542
Checksum:i787EBCD8761C8700
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti27I → V in AAR39430 (Ref. 1) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01814843 – 78Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY487420 mRNA Translation: AAR39430.1
AL139220 Genomic DNA No translation available.
BC033868 mRNA Translation: AAH33868.1
CCDSiCCDS507.1 [Q8N4L8-1]
RefSeqiNP_689712.1, NM_152499.2 [Q8N4L8-1]
XP_016855930.1, XM_017000441.1 [Q8N4L8-2]
UniGeneiHs.632394

Genome annotation databases

EnsembliENST00000372318; ENSP00000361392; ENSG00000159214 [Q8N4L8-1]
GeneIDi149473
KEGGihsa:149473
UCSCiuc001clj.4 human [Q8N4L8-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiCCD24_HUMAN
AccessioniPrimary (citable) accession number: Q8N4L8
Secondary accession number(s): Q6RWT2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: October 1, 2002
Last modified: June 20, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health