Q8N4D4 (Q8N4D4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP13A2 protein EMBL AAH34575.1

Gene names

Name:

ATP13A2 EMBL AAH34575.1

Organism

Homo sapiens (Human) EMBL AAH34575.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1088 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Magnesium SAAS SAAS023306 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 SAAS SAAS023306
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cation-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH34575.1

Sequences

	Sequence		Length	Mass (Da)
	Q8N4D4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 63D6A9E5EFFB2888	FASTA	1,088	118,812
	10 20 30 40 50 60 RDKEDSSWQL FTVQVQTEAI GEGSLEPSPQ SQAEDGRSQA AVGAVPEGAW KDTAQLHKSE 70 80 90 100 110 120 EAVSVGQKRV LRYYLFQGQR YIWIETQQAF YQVSLLDHGR SCDDVHRSRH GLSLQDQMVR 130 140 150 160 170 180 KAIYGPNVIS IPVKSYPQLL VDEALNPYYG FQAFSIALWL ADHYYWYALC IFLISSISIC 190 200 210 220 230 240 LSLYKTRKQS QTLRDMVKLS MRVCVCRPGG EEEWVDSSEL VPGDCLVLPQ EGGLMPCDAA 250 260 270 280 290 300 LVAGECMVNE SSLTGESIPV LKTALPEGLG PYCAETHRRH TLFCGTLILQ ARAYVGPHVL 310 320 330 340 350 360 AVVTRTGFCT AKGGLVSSIL HPRPINFKFY KHSMKFVAAL SVLALLGTIY SIFILYRNRV 370 380 390 400 410 420 PLNEIVIRAL DLVTVVVPPA LPAAMTVCTL YAQSRLRRQG IFCIHPLRIN LGGKLQLVCF 430 440 450 460 470 480 DKTGTLTEDG LDVMGVVPLK GQAFLPLVPE PRRLPVGPLL RALATCHALS RLQDTPVGDP 490 500 510 520 530 540 MDLKMVESTG WVLEEEPAAD SAFGTQVLAV MRPPLWEPQL QAMEEPPVPV SVLHRFPFSS 550 560 570 580 590 600 ALQRMSVVVA WPGATQPEAY VKGSPELVAG LCNPETVPTD FAQMLQSYTA AGYRVVALAS 610 620 630 640 650 660 KPLPTVPSLE AAQQLTRDTV EGDLSLLGLL VMRNLLKPQT TPVIQALRRT RIRAVMVTGD 670 680 690 700 710 720 NLQTAVTVAR GCGMVAPQEH LIIVHATHPE RGQPASLEFL PMESPTAVNG VKDPDQAASY 730 740 750 760 770 780 TVEPDPRSRH LALSGPTFGI IVKHFPKLLP KVLVQGTVFA RMAPEQKTEL VCELQKLQYC 790 800 810 820 830 840 VGMCGDGAND CGALKAADVG ISLSQAEASV VSPFTSSMAS IECVPMVIRE GRCSLDTSFS 850 860 870 880 890 900 VFKYMALYSL TQFISVLILY TINTNLGDLQ FLAIDLVITT TVAVLMSRTG PALVLGRVRP 910 920 930 940 950 960 PGALLSVPVL SSLLLQMVLV TGVQLGGYFL TLAQPWFVPL NRTVAAPDNL PNYENTVVFS 970 980 990 1000 1010 1020 LSSFQYLILA AAVSKGAPFR RPLYTNVPFL VALALLSSVL VGLVLVPGLL QGPLALRNIT 1030 1040 1050 1060 1070 1080 DTGFKLLLLG LVTLNFVGAF MLESVLDQCL PACLRRLRPK RASKKRFKQL ERELAEQPWP PLPAGPLR

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Cervix EMBL AAH34575.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC034575 mRNA. Translation: AAH34575.1.
IPI	IPI00015154.
UniGene	Hs.128866.
3D structure databases
ProteinModelPortal	Q8N4D4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8N4D4.
Proteomic databases
PRIDE	Q8N4D4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG065757.
Gene expression databases
ArrayExpress	Q8N4D4.
Bgee	Q8N4D4.
Family and domain databases
Gene3D	2.70.150.10. 1 hit. 3.40.1110.10. 2 hits. 3.40.50.1000. 2 hits.
InterPro	IPR004014. ATPase_P-typ_cation-transptr_N. IPR006544. ATPase_P-typ_Cation_typ_V. IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. [Graphical view]
PANTHER	PTHR24093. PTHR24093. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 2 hits. TIGR01657. P-ATPase-V. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ATP13A2. human.

Entry information

Entry name

Q8N4D4_HUMAN

Accession

Primary (citable) accession number: Q8N4D4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.