SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8N4C7

- STX19_HUMAN

UniProt

Q8N4C7 - STX19_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Syntaxin-19

Gene
STX19
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: IntAct

GO - Biological processi

  1. intracellular protein transport Source: InterPro
  2. vesicle-mediated transport Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-19
Gene namesi
Name:STX19
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:19300. STX19.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670857.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 294294Syntaxin-19PRO_0000263709Add
BLAST

Proteomic databases

PaxDbiQ8N4C7.
PRIDEiQ8N4C7.

PTM databases

PhosphoSiteiQ8N4C7.

Expressioni

Gene expression databases

BgeeiQ8N4C7.
CleanExiHS_STX19.
GenevestigatoriQ8N4C7.

Organism-specific databases

HPAiHPA030604.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KDM1AO603412EBI-8484990,EBI-710124
SUV39H1O434632EBI-8484990,EBI-349968

Protein-protein interaction databases

BioGridi136105. 2 interactions.
IntActiQ8N4C7. 2 interactions.
MINTiMINT-6940674.
STRINGi9606.ENSP00000320679.

Structurei

3D structure databases

ProteinModelPortaliQ8N4C7.
SMRiQ8N4C7. Positions 48-288.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini209 – 27163t-SNARE coiled-coil homologyAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi280 – 29112Cys-richAdd
BLAST

Sequence similaritiesi

Belongs to the syntaxin family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG270635.
HOGENOMiHOG000286023.
HOVERGENiHBG099780.
InParanoidiQ8N4C7.
KOiK08487.
OMAiHFQQTMF.
OrthoDBiEOG7X9G7R.
PhylomeDBiQ8N4C7.
TreeFamiTF313763.

Family and domain databases

InterProiIPR015708. STX19.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR19957:SF29. PTHR19957:SF29. 1 hit.
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N4C7-1 [UniParc]FASTAAdd to Basket

« Hide

MKDRLQELKQ RTKEIELSRD SHVSTTETEE QGVFLQQAVI YEREPVAERH    50
LHEIQKLQES INNLADNVQK FGQQQKSLVA SMRRFSLLKR ESTITKEIKI 100
QAEYINRSLN DLVKEVKKSE VENGPSSVVT RILKSQHAAM FRHFQQIMFI 150
YNDTIAAKQE KCKTFILRQL EVAGKEMSEE DVNDMLHQGK WEVFNESLLT 200
EINITKAQLS EIEQRHKELV NLENQIKDLR DLFIQISLLV EEQGESINNI 250
EMTVNSTKEY VNNTKEKFGL AVKYKKRNPC RVLCCWCCPC CSSK 294
Length:294
Mass (Da):34,324
Last modified:October 1, 2002 - v1
Checksum:i1A7FE896916DCE57
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF461456 mRNA. Translation: AAQ04780.1.
BC034696 mRNA. Translation: AAH34696.1.
CCDSiCCDS33793.1.
RefSeqiNP_001001850.1. NM_001001850.2.
XP_005247512.1. XM_005247455.2.
XP_005247513.1. XM_005247456.1.
UniGeneiHs.679768.

Genome annotation databases

EnsembliENST00000315099; ENSP00000320679; ENSG00000178750.
GeneIDi415117.
KEGGihsa:415117.
UCSCiuc003drh.1. human.

Polymorphism databases

DMDMi74728839.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF461456 mRNA. Translation: AAQ04780.1 .
BC034696 mRNA. Translation: AAH34696.1 .
CCDSi CCDS33793.1.
RefSeqi NP_001001850.1. NM_001001850.2.
XP_005247512.1. XM_005247455.2.
XP_005247513.1. XM_005247456.1.
UniGenei Hs.679768.

3D structure databases

ProteinModelPortali Q8N4C7.
SMRi Q8N4C7. Positions 48-288.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 136105. 2 interactions.
IntActi Q8N4C7. 2 interactions.
MINTi MINT-6940674.
STRINGi 9606.ENSP00000320679.

PTM databases

PhosphoSitei Q8N4C7.

Polymorphism databases

DMDMi 74728839.

Proteomic databases

PaxDbi Q8N4C7.
PRIDEi Q8N4C7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000315099 ; ENSP00000320679 ; ENSG00000178750 .
GeneIDi 415117.
KEGGi hsa:415117.
UCSCi uc003drh.1. human.

Organism-specific databases

CTDi 415117.
GeneCardsi GC03M093733.
HGNCi HGNC:19300. STX19.
HPAi HPA030604.
neXtProti NX_Q8N4C7.
PharmGKBi PA142670857.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG270635.
HOGENOMi HOG000286023.
HOVERGENi HBG099780.
InParanoidi Q8N4C7.
KOi K08487.
OMAi HFQQTMF.
OrthoDBi EOG7X9G7R.
PhylomeDBi Q8N4C7.
TreeFami TF313763.

Miscellaneous databases

GenomeRNAii 415117.
NextBioi 108685.
PROi Q8N4C7.

Gene expression databases

Bgeei Q8N4C7.
CleanExi HS_STX19.
Genevestigatori Q8N4C7.

Family and domain databases

InterProi IPR015708. STX19.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view ]
PANTHERi PTHR19957:SF29. PTHR19957:SF29. 1 hit.
Pfami PF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view ]
SMARTi SM00397. t_SNARE. 1 hit.
[Graphical view ]
SUPFAMi SSF47661. SSF47661. 1 hit.
PROSITEi PS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, expression and characterization of a novel human SNARE protein syntaxin-19 in MDCK cells."
    Zhang Z., Low S.H., Li X., Miura M., Kudo N., Hofmann K., Weimbs T.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Skin.

Entry informationi

Entry nameiSTX19_HUMAN
AccessioniPrimary (citable) accession number: Q8N4C7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi