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Protein

Protein limb expression 1 homolog

Gene

LIX1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein limb expression 1 homolog
Gene namesi
Name:LIX1
Synonyms:C5orf11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000145721.11
HGNCiHGNC:18581 LIX1
MIMi610466 gene
neXtProtiNX_Q8N485

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

DisGeNETi167410
OpenTargetsiENSG00000145721
PharmGKBiPA38353

Polymorphism and mutation databases

BioMutaiLIX1
DMDMi126302565

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002328691 – 282Protein limb expression 1 homologAdd BLAST282

Proteomic databases

PaxDbiQ8N485
PeptideAtlasiQ8N485
PRIDEiQ8N485
ProteomicsDBi71894

PTM databases

PhosphoSitePlusiQ8N485

Expressioni

Gene expression databases

BgeeiENSG00000145721
CleanExiHS_LIX1
ExpressionAtlasiQ8N485 baseline and differential
GenevisibleiQ8N485 HS

Organism-specific databases

HPAiHPA058426

Interactioni

Protein-protein interaction databases

BioGridi127946, 2 interactors
IntActiQ8N485, 2 interactors
STRINGi9606.ENSP00000274382

Structurei

3D structure databases

ProteinModelPortaliQ8N485
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LIX1 family.Curated

Phylogenomic databases

eggNOGiENOG410IH13 Eukaryota
ENOG410XRZR LUCA
GeneTreeiENSGT00390000005869
HOGENOMiHOG000237359
HOVERGENiHBG079509
InParanoidiQ8N485
OMAiEFQELMI
OrthoDBiEOG091G0KAJ
PhylomeDBiQ8N485
TreeFamiTF324035

Family and domain databases

InterProiView protein in InterPro
IPR029270 LIX1
PfamiView protein in Pfam
PF14954 LIX1, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N485-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRTLESLRH IIAQVLPHRD PALVFKDLNV VSMLQEFWES KQQQKAAFPS
60 70 80 90 100
EGVVVYESLP APGPPFVSYV TLPGGSCFGN FQCCLSRAEA RRDAAKVALI
110 120 130 140 150
NSLFNELPSR RITKEFIMES VQEAVASTSG TLDDADDPST SVGAYHYMLE
160 170 180 190 200
SNMGKTMLEF QELMTIFQLL HWNGSLKALR ETKCSRQEVI SYYSQYSLDE
210 220 230 240 250
KMRSHMALDW IMKERDSPGI VSQELRMALR QLEEARKAGQ ELRFYKEKKE
260 270 280
ILSLALTQIC SDPDTSSPSD DQLSLTALCG YH
Length:282
Mass (Da):31,891
Last modified:February 20, 2007 - v2
Checksum:iB5642D1123C3CEF6
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0260393R → I1 PublicationCorresponds to variant dbSNP:rs11558079Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098400 mRNA Translation: BAC05298.1
AK291034 mRNA Translation: BAF83723.1
CH471084 Genomic DNA Translation: EAW96087.1
BC036467 mRNA Translation: AAH36467.1
CCDSiCCDS4088.1
RefSeqiNP_694966.3, NM_153234.4
UniGeneiHs.656702

Genome annotation databases

EnsembliENST00000274382; ENSP00000274382; ENSG00000145721
GeneIDi167410
KEGGihsa:167410
UCSCiuc003kmy.5 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiLIX1_HUMAN
AccessioniPrimary (citable) accession number: Q8N485
Secondary accession number(s): A8K4R9, Q8N7I2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: February 20, 2007
Last modified: June 20, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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