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Q8N355

- Q8N355_HUMAN

UniProt

Q8N355 - Q8N355_HUMAN

Protein
Submitted name:

IGL@ protein

Gene

IGL@

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    IGL@ proteinImported
    Gene namesi
    Name:IGL@Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8N355.

    Interactioni

    Protein-protein interaction databases

    IntActiQ8N355. 4 interactions.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4FQQX-ray2.42A/C/E/L20-234[»]
    4HK0X-ray2.50B/D22-234[»]
    4HK3X-ray3.00N22-234[»]
    ProteinModelPortaliQ8N355.
    SMRiQ8N355. Positions 21-234.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Immunoglobulin domainSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000059537.
    HOVERGENiHBG018013.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00407. IGc1. 1 hit.
    SM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 2 hits.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8N355-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAWTVLLLGL LSHCTGSVTS YVLTQPPSVS VAPGQTARIT CGGNNIGSKS    50
    VHWYQQKPGQ APVLVVYDDS DRPSGIPERF SGSNSGNTAT LTISRVDAGD 100
    EADYYCQLWD SSSDHPVVFG GGTKLTVLGQ PKAAPSVTLF PPSSEELQAN 150
    KATLVCLISD FYPGAVTVAW KADSSPVKAG VETTTPSKQS NNKYAASSYL 200
    SLTPEQWKSH RSYSCQVTHE GSTVEKTVAP TECS 234
    Length:234
    Mass (Da):24,793
    Last modified:October 1, 2002 - v1
    Checksum:iCC848CAEBA4A9D63
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC028090 mRNA. Translation: AAH28090.1.
    PIRiS09713.
    S12441.
    S30527.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC028090 mRNA. Translation: AAH28090.1 .
    PIRi S09713.
    S12441.
    S30527.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4FQQ X-ray 2.42 A/C/E/L 20-234 [» ]
    4HK0 X-ray 2.50 B/D 22-234 [» ]
    4HK3 X-ray 3.00 N 22-234 [» ]
    ProteinModelPortali Q8N355.
    SMRi Q8N355. Positions 21-234.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8N355. 4 interactions.

    Proteomic databases

    PRIDEi Q8N355.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000059537.
    HOVERGENi HBG018013.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00407. IGc1. 1 hit.
    SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 2 hits.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system."
      Hughes-Jones N.C., Bye J.M., Beale D., Coadwell J.
      Biochem. J. 268:135-140(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Structure and expression of the human immunoglobulin lambda genes."
      Vasicek T.J., Leder P.
      J. Exp. Med. 172:609-620(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    4. Cited for: X-RAY CRYSTALLOGRAPHY (2.42 ANGSTROMS) OF 20-234.
    5. Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 22-234.

    Entry informationi

    Entry nameiQ8N355_HUMAN
    AccessioniPrimary (citable) accession number: Q8N355
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3