Q8N307 (MUC20_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mucin-20
Short name=MUC-20

Gene names

Name:	MUC20
Synonyms:	KIAA1359
ORF Names:	UNQ2782/PRO7170

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	709 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. Ref.7
Subunit structure	Interacts with MET; oligomerization increases affinity for MET. Ref.7
Subcellular location	Secreted Potential. Apical cell membrane. Basolateral cell membrane. Cell projection › microvillus membrane Ref.1.
Tissue specificity	Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis. Ref.1 Ref.9
Polymorphism	The region encoding the tandem repeats is highly polymorphic. Divergence of the number of tandem repeats was seen in different cDNA libraries.
Sequence caution	The sequence AAQ88814.1 differs from that shown. Reason: Frameshift at position 638. The sequence BAA92597.1 differs from that shown. Reason: Dubious isoform. Probable cloning artifact.

Ontologies

Keywords
Cellular component	Cell membrane Cell projection Membrane Secreted
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Signal
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	O-glycan processing Traceable author statement. Source: Reactome activation of MAPK activity Inferred from electronic annotation. Source: Compara hepatocyte growth factor receptor signaling pathway Inferred from electronic annotation. Source: Compara post-translational protein modification Traceable author statement. Source: Reactome protein homooligomerization Inferred from direct assay Ref.7. Source: MGI
Cellular_component	Golgi lumen Traceable author statement. Source: Reactome apical plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell basal plasma membrane Inferred from direct assay Ref.7. Source: MGI extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell microvillus membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8N307-1)

Also known as: hMUC20-L;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8N307-3)

Also known as: hMUC20-S;

The sequence of this isoform differs from the canonical sequence as follows:
     1-35: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 709	684	Mucin-20		PRO_0000317469
Regions
	Repeat	173 – 192	20	1
	Repeat	193 – 211	19	2
	Repeat	212 – 230	19	3
	Repeat	231 – 249	19	4
	Repeat	250 – 268	19	5
	Repeat	269 – 287	19	6
	Repeat	288 – 306	19	7
	Repeat	307 – 325	19	8
	Repeat	326 – 344	19	9
	Repeat	345 – 363	19	10
	Repeat	364 – 382	19	11
	Repeat	383 – 400	18	12; approximate
	Region	173 – 400	228	12 X 20 AA approximate tandem repeats of S-S-E-S-S-A-S-S-D-S-P-H-P-V-I-T-P-S-R-A
	Region	450 – 656	207	Involved in oligomerization
	Region	657 – 709	53	Interaction with MET
	Compositional bias	173 – 389	217	Ser-rich
	Compositional bias	585 – 652	68	Thr-rich
Amino acid modifications
	Glycosylation	423	1	N-linked (GlcNAc...) Potential
	Glycosylation	616	1	N-linked (GlcNAc...) Potential
	Glycosylation	622	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 35	35	Missing in isoform 2.		VSP_030980
	Natural variant	3	1	C → S. Corresponds to variant rs7627924 [ dbSNP | Ensembl ].		VAR_038536
	Natural variant	18	1	V → G. Corresponds to variant rs1811139 [ dbSNP | Ensembl ].		VAR_038537
	Natural variant	130 – 376	247	Missing.		VAR_054139
	Natural variant	184 – 354	171	Missing.		VAR_054140
	Natural variant	203 – 354	152	Missing.		VAR_054141
	Natural variant	241 – 354	114	Missing.		VAR_054142
	Natural variant	442	1	T → I. Ref.1 Ref.2 Ref.3 Ref.5 Corresponds to variant rs2550232 [ dbSNP | Ensembl ].		VAR_038538
	Natural variant	483 – 533	51	Missing.		VAR_054143
	Natural variant	514	1	G → R. Corresponds to variant rs3828410 [ dbSNP | Ensembl ].		VAR_056641
	Natural variant	590	1	P → L. Ref.5 Corresponds to variant rs3828408 [ dbSNP | Ensembl ].		VAR_038539
	Natural variant	666	1	R → W. Corresponds to variant rs11923495 [ dbSNP | Ensembl ].		VAR_038540
	Natural variant	671	1	S → C. Corresponds to variant rs3762739 [ dbSNP | Ensembl ].		VAR_038541
Experimental info
	Sequence conflict	75	1	I → V in AAH29267. Ref.5
	Sequence conflict	136	1	R → E in BAD06718. Ref.1
	Sequence conflict	136	1	R → E in BAD06720. Ref.1
	Sequence conflict	136	1	R → E in AAQ88814. Ref.2
	Sequence conflict	136	1	R → E in BAB55035. Ref.3
	Sequence conflict	136	1	R → E in AAH29267. Ref.5
	Sequence conflict	136	1	R → E in AAH44243. Ref.5
	Sequence conflict	182	1	S → G in BAD06718. Ref.1
	Sequence conflict	182	1	S → G in BAD06720. Ref.1
	Sequence conflict	182	1	S → G in AAQ88814. Ref.2
	Sequence conflict	182	1	S → G in BAB55035. Ref.3
	Sequence conflict	182	1	S → G in AAH29267. Ref.5
	Sequence conflict	182	1	S → G in AAH44243. Ref.5
	Sequence conflict	221	1	P → L in BAA92597. Ref.6
	Sequence conflict	407	1	T → A in BAB55035. Ref.3
	Sequence conflict	433	1	T → A in BAC11428. Ref.3
	Sequence conflict	444	1	L → P in AAH29267. Ref.5
	Sequence conflict	493	1	D → H in BAD06718. Ref.1
	Sequence conflict	493	1	D → H in BAD06720. Ref.1
	Sequence conflict	493	1	D → H in AAQ88814. Ref.2
	Sequence conflict	493	1	D → H in BAC11428. Ref.3
	Sequence conflict	493	1	D → H in AAH44243. Ref.5
	Sequence conflict	496	1	V → I in AAH29267. Ref.5
	Sequence conflict	505 – 506	2	AT → TI in AAH29267. Ref.5
	Sequence conflict	523 – 527	5	VTVSR → ATG in AAH29267. Ref.5
	Sequence conflict	592	1	M → T in AAH29267. Ref.5
	Sequence conflict	654	1	V → M in AAH29267. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (hMUC20-L) [UniParc]. Last modified January 11, 2011. Version 3. Checksum: DD344A6014D39172	FASTA	709	71,982
	10 20 30 40 50 60 MGCLWGLALP LFFFCWEVGV SGSSAGPSTR RADTAMTTDD TEVPAMTLAP GHAALETQTL 70 80 90 100 110 120 SAETSSRAST PAGPIPEAET RGAKRISPAR ETRSFTKTSP NFMVLIATSV ETSAASGSPE 130 140 150 160 170 180 GAGMTTVQTI TGSDPREAIF DTLCTDDSSE EAKTLTMDIL TLAHTSTEAK GLSSESSASS 190 200 210 220 230 240 DSPHPVITPS RASESSASSD GPHPVITPSR ASESSASSDG PHPVITPSRA SESSASSDGP 250 260 270 280 290 300 HPVITPSRAS ESSASSDGPH PVITPSRASE SSASSDGPHP VITPSRASES SASSDGPHPV 310 320 330 340 350 360 ITPSRASESS ASSDGPHPVI TPSRASESSA SSDGPHPVIT PSRASESSAS SDGLHPVITP 370 380 390 400 410 420 SRASESSASS DGPHPVITPS RASESSASSD GPHPVITPSW SPGSDVTLLA EALVTVTNIE 430 440 450 460 470 480 VINCSITEIE TTTSSIPGAS DTDLIPTEGV KASSTSDPPA LPDSTEAKPH ITEVTASAET 490 500 510 520 530 540 LSTAGTTESA APDATVGTPL PTNSATEREV TAPGATTLSG ALVTVSRNPL EETSALSVET 550 560 570 580 590 600 PSYVKVSGAA PVSIEAGSAV GKTTSFAGSS ASSYSPSEAA LKNFTPSETP TMDIATKGPF 610 620 630 640 650 660 PTSRDPLPSV PPTTTNSSRG TNSTLAKITT SAKTTMKPPT ATPTTARTRP TTDVSAGENG 670 680 690 700 GFLLLRLSVA SPEDLTDPRV AERLMQQLHR ELHAHAPHFQ VSLLRVRRG
	Isoform 2 (hMUC20-S) [UniParc]. Checksum: 2834A68A1250F5E1	FASTA	674	68,308
	10 20 30 40 50 60 MTTDDTEVPA MTLAPGHAAL ETQTLSAETS SRASTPAGPI PEAETRGAKR ISPARETRSF 70 80 90 100 110 120 TKTSPNFMVL IATSVETSAA SGSPEGAGMT TVQTITGSDP REAIFDTLCT DDSSEEAKTL 130 140 150 160 170 180 TMDILTLAHT STEAKGLSSE SSASSDSPHP VITPSRASES SASSDGPHPV ITPSRASESS 190 200 210 220 230 240 ASSDGPHPVI TPSRASESSA SSDGPHPVIT PSRASESSAS SDGPHPVITP SRASESSASS 250 260 270 280 290 300 DGPHPVITPS RASESSASSD GPHPVITPSR ASESSASSDG PHPVITPSRA SESSASSDGP 310 320 330 340 350 360 HPVITPSRAS ESSASSDGLH PVITPSRASE SSASSDGPHP VITPSRASES SASSDGPHPV 370 380 390 400 410 420 ITPSWSPGSD VTLLAEALVT VTNIEVINCS ITEIETTTSS IPGASDTDLI PTEGVKASST 430 440 450 460 470 480 SDPPALPDST EAKPHITEVT ASAETLSTAG TTESAAPDAT VGTPLPTNSA TEREVTAPGA 490 500 510 520 530 540 TTLSGALVTV SRNPLEETSA LSVETPSYVK VSGAAPVSIE AGSAVGKTTS FAGSSASSYS 550 560 570 580 590 600 PSEAALKNFT PSETPTMDIA TKGPFPTSRD PLPSVPPTTT NSSRGTNSTL AKITTSAKTT 610 620 630 640 650 660 MKPPTATPTT ARTRPTTDVS AGENGGFLLL RLSVASPEDL TDPRVAERLM QQLHRELHAH 670 APHFQVSLLR VRRG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney." Higuchi T., Orita T., Nakanishi S., Katsuya K., Watanabe H., Yamasaki Y., Waga I., Nanayama T., Yamamoto Y., Munger W., Sun H.-W., Falk R.J., Jennette J.C., Alcorta D.A., Li H., Yamamoto T., Saito Y., Nakamura M. J. Biol. Chem. 279:1968-1979(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2), VARIANTS 184-HIS--LEU-354 DEL; 241-HIS--LEU-354 DEL AND ILE-442, POLYMORPHISM, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Kidney.
[2]	"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M. Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS 184-HIS--LEU-354 DEL AND ILE-442.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS 184-HIS--LEU-354 DEL; ILE-442 AND 483-THR--THR-533 DEL. Tissue: Embryo and Placenta.
[4]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS 184-HIS--LEU-354 DEL; 203-HIS--LEU-354; DEL ILE-442 AND LEU-590. Tissue: Brain and Colon.
[6]	"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 26-638 (ISOFORM 1), VARIANT 241-HIS--LEU-354 DEL. Tissue: Brain.
[7]	"MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met." Higuchi T., Orita T., Katsuya K., Yamasaki Y., Akiyama K., Li H., Yamamoto T., Saito Y., Nakamura M. Mol. Cell. Biol. 24:7456-7468(2004) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, INTERACTION WITH MET.
[8]	"Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy." Li G., Zhang H., Lv J., Hou P., Wang H. Am. J. Nephrol. 26:43-49(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TANDEM REPEATS POLYMORPHISM.
[9]	"Mucin gene expression in human male urogenital tract epithelia." Russo C.L., Spurr-Michaud S., Tisdale A., Pudney J., Anderson D., Gipson I.K. Hum. Reprod. 21:2783-2793(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
+	Additional computationally mapped references.

Web resources

Mucin database

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB098731 mRNA. Translation: BAD06718.1. AB098733 Genomic DNA. Translation: BAD06720.1. AY358449 mRNA. Translation: AAQ88814.1. Frameshift. AK027314 mRNA. Translation: BAB55035.1. AK075138 mRNA. Translation: BAC11428.1. AC069513 Genomic DNA. No translation available. BC029267 mRNA. Translation: AAH29267.1. BC044243 mRNA. Translation: AAH44243.1. AB037780 mRNA. Translation: BAA92597.1. Sequence problems.
IPI	IPI00002234. IPI00885179.
RefSeq	NP_001091986.1. NM_001098516.1. NP_689886.2. NM_152673.2.
UniGene	Hs.308992.
3D structure databases
ProteinModelPortal	Q8N307.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8N307. 2 interactions.
STRING	9606.ENSP00000396774.
PTM databases
PhosphoSite	Q8N307.
Polymorphism databases
DMDM	167017384.
Proteomic databases
PaxDb	Q8N307.
PRIDE	Q8N307.
Protocols and materials databases
DNASU	200958.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000445522; ENSP00000405629; ENSG00000176945. ENST00000447234; ENSP00000414350; ENSG00000176945.
GeneID	200958.
KEGG	hsa:200958.
Organism-specific databases
CTD	200958.
GeneCards	GC03P195343.
HGNC	HGNC:23282. MUC20.
MIM	610360. gene.
neXtProt	NX_Q8N307.
PharmGKB	PA134939730.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG84731.
HOVERGEN	HBG108160.
OrthoDB	EOG4BRWM6.
Enzyme and pathway databases
Reactome	REACT_17015. Metabolism of proteins.
Gene expression databases
ArrayExpress	Q8N307.
Bgee	Q8N307.
CleanEx	HS_MUC20.
Genevestigator	Q8N307.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	200958.
NextBio	90029.
SOURCE	Search...

Entry information

Entry name

MUC20_HUMAN

Accession

Primary (citable) accession number: Q8N307
Secondary accession number(s): Q6UX97 , Q76I83, Q76I85, Q86ST8, Q8NBY6, Q96KA1, Q9P2I8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 11, 2011
Last modified:	April 3, 2013
This is version 72 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.