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Protein
Submitted name:

ZFHX3 protein

Gene

ZFHX3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ZFHX3 proteinImported
Gene namesi
Name:ZFHX3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162409676.

PTM / Processingi

Proteomic databases

PaxDbiQ8N2Y6.

Expressioni

Gene expression databases

GenevisibleiQ8N2Y6. HS.

Interactioni

Protein-protein interaction databases

IntActiQ8N2Y6. 1 interaction.
STRINGi9606.ENSP00000268489.

Structurei

3D structure databases

ProteinModelPortaliQ8N2Y6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini446 – 47631C2H2-typeInterPro annotationAdd
BLAST
Domaini487 – 50923C2H2-typeInterPro annotationAdd
BLAST
Domaini631 – 66232C2H2-typeInterPro annotationAdd
BLAST
Domaini682 – 71130C2H2-typeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili801 – 83737Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1146. Eukaryota.
ENOG410XYHC. LUCA.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
IPR003604. Znf_U1.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 10 hits.
SM00451. ZnF_U1. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N2Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLGGGQLVS EELMNLGESF IQTNDPSLKL FQCAVCNKFT TDNLDMLGLH
60 70 80 90 100
MNVERSLSED EWKAVMGDSY QCKLCRYNTQ LKANFQLHCK TDKHVQKYQL
110 120 130 140 150
VAHIKEGGKA NEWRLKCVAI GNPVHLKCNA CDYYTNSLEK LRLHTVNSRH
160 170 180 190 200
EASLKLYKHL QQHESGVEGE SCYYHCVLCN YSTKAKLNLI QHVRSMKHQR
210 220 230 240 250
SESLRKLQRL QKGLPEEDED LGQIFTIRRC PSTDPEEAIE DVEGPSETAA
260 270 280 290 300
DPEELAKDQE GGASSSQAEK ELTDSPATSK RISFPGSSES PLSSKRPKTA
310 320 330 340 350
EEIKPEQMYQ CPYCKYSNAD VNRLRVHAMT QHSVQPMLRC PLCQDMLNNK
360 370 380 390 400
IHLQLHLTHL HSVAPDCVEK LIMTVTTPEM VMPSSMFLPA AVPDRDGNSN
410 420 430 440 450
LEEAGKQPET SEDLGKNILP SASTEQSGDL KPSPADPGSV REDSGFICWK
460 470 480 490 500
KGCNQVFKTS AALQTHFNEV HAKRPQLPVS DRHVYKYRCN QCSLAFKTIE
510 520 530 540 550
KLQLHSQYHV IRAATMCCLC QRSFRTFQAL KKHLETSHLE LSEADIQQLY
560 570 580 590 600
GGLLANGDLL AMGDPTLAED HTIIVEEDKE EESDLEDKQS PTGSDSGSVQ
610 620 630 640 650
EDSGSEPKRA LPFRKGPNFT MEKFLDPSRP YKCTVCKESF TQKNILLVHY
660 670 680 690 700
NSVSHLHKLK RALQESATGQ PEPTSSPDNK PFKCNTCNVA YSQSSTLEIH
710 720 730 740 750
MRSVLHQTKA RAAKLEAASG SSNGTGNSSS ISLSSSTPSP VSTSGSNTFT
760 770 780 790 800
TSNPSSAGIA PSSNLLSQVP TESVGMPPLG NPIGANIASP SEPKEANRKK
810 820 830 840 850
LADMIASRQQ QQQQQQQQQQ QQQQQQQAQT LAQAQAQVQA HLQQELQQQA
860 870 880
ALIQSQLFNP TLLPHFPMTT ETLLQLQQQQ HPLYPL
Length:886
Mass (Da):98,584
Last modified:October 1, 2002 - v1
Checksum:iD53825266E5B7EC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029653 mRNA. Translation: AAH29653.1.
RefSeqiNP_008816.3. NM_006885.3.
UniGeneiHs.598297.

Genome annotation databases

GeneIDi463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029653 mRNA. Translation: AAH29653.1.
RefSeqiNP_008816.3. NM_006885.3.
UniGeneiHs.598297.

3D structure databases

ProteinModelPortaliQ8N2Y6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8N2Y6. 1 interaction.
STRINGi9606.ENSP00000268489.

Proteomic databases

PaxDbiQ8N2Y6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi463.

Organism-specific databases

CTDi463.
PharmGKBiPA162409676.

Phylogenomic databases

eggNOGiKOG1146. Eukaryota.
ENOG410XYHC. LUCA.

Miscellaneous databases

ChiTaRSiZFHX3. human.
GenomeRNAii463.

Gene expression databases

GenevisibleiQ8N2Y6. HS.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
IPR003604. Znf_U1.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 10 hits.
SM00451. ZnF_U1. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: CervixImported.

Entry informationi

Entry nameiQ8N2Y6_HUMAN
AccessioniPrimary (citable) accession number: Q8N2Y6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.