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Q8N2U0 (TM256_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein 256
Gene names
Name:TMEM256
Synonyms:C17orf61
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length113 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the TMEM256 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential
Chain30 – 11384Transmembrane protein 256
PRO_0000287170

Regions

Topological domain30 – 6334Extracellular Potential
Transmembrane64 – 8421Helical; Potential
Topological domain85 – 928Cytoplasmic Potential
Transmembrane93 – 11321Helical; Potential

Amino acid modifications

Modified residue431N6-acetyllysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8N2U0 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 3184A3767F5ABB0E

FASTA11311,742
        10         20         30         40         50         60 
MAGPAAAFRR LGALSGAAAL GFASYGAHGA QFPDAYGKEL FDKANKHHFL HSLALLGVPH 

        70         80         90        100        110 
CRKPLWAGLL LASGTTLFCT SFYYQALSGD PSIQTLAPAG GTLLLLGWLA LAL 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Mammary gland.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC030270 mRNA. Translation: AAH30270.1.
CCDSCCDS11102.1.
RefSeqNP_689979.1. NM_152766.3.
UniGeneHs.730789.

3D structure databases

ProteinModelPortalQ8N2U0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid129054. 7 interactions.
IntActQ8N2U0. 3 interactions.
STRING9606.ENSP00000301939.

PTM databases

PhosphoSiteQ8N2U0.

Polymorphism databases

DMDM74728725.

Proteomic databases

MaxQBQ8N2U0.
PaxDbQ8N2U0.
PRIDEQ8N2U0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000302422; ENSP00000301939; ENSG00000205544.
GeneID254863.
KEGGhsa:254863.
UCSCuc002ggs.3. human.

Organism-specific databases

CTD254863.
GeneCardsGC17M007307.
HGNCHGNC:28618. TMEM256.
neXtProtNX_Q8N2U0.
PharmGKBPA142672244.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG257219.
HOGENOMHOG000252654.
HOVERGENHBG095157.
InParanoidQ8N2U0.
OMAGAHGFKN.
OrthoDBEOG7VMP6D.
PhylomeDBQ8N2U0.
TreeFamTF300271.

Gene expression databases

ArrayExpressQ8N2U0.
BgeeQ8N2U0.
CleanExHS_C17orf61.
GenevestigatorQ8N2U0.

Family and domain databases

InterProIPR006696. DUF423.
[Graphical view]
PfamPF04241. DUF423. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi254863.
NextBio92403.

Entry information

Entry nameTM256_HUMAN
AccessionPrimary (citable) accession number: Q8N2U0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 17

Human chromosome 17: entries, gene names and cross-references to MIM