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Protein
Submitted name:

cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chain

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chainImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30282

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500431106420 – 529Sequence analysisAdd BLAST510

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi273 ↔ 290PROSITE-ProRule annotation
Disulfide bondi292 ↔ 301PROSITE-ProRule annotation
Disulfide bondi355 ↔ 364PROSITE-ProRule annotation
Disulfide bondi383 ↔ 395PROSITE-ProRule annotation
Disulfide bondi403 ↔ 412PROSITE-ProRule annotation
Disulfide bondi450 ↔ 459PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiQ8N2D6
PRIDEiQ8N2D6

Expressioni

Gene expression databases

GenevisibleiQ8N2D6 HS

Structurei

3D structure databases

ProteinModelPortaliQ8N2D6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 270Laminin N-terminalInterPro annotationAdd BLAST240
Domaini271 – 326Laminin EGF-likeInterPro annotationAdd BLAST56
Domaini327 – 382Laminin EGF-likeInterPro annotationAdd BLAST56
Domaini383 – 429Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini430 – 481Laminin EGF-likeInterPro annotationAdd BLAST52

Keywords - Domaini

Laminin EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IP68 Eukaryota
ENOG4111F9V LUCA
HOGENOMiHOG000286017
KOiK06247

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR002049 Laminin_EGF
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00053 Laminin_EGF, 4 hits
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00180 EGF_Lam, 4 hits
SM00136 LamNT, 1 hit
PROSITEiView protein in PROSITE
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 4 hits
PS51117 LAMININ_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N2D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAALLLGL ALLAPRAAGA GMGACYDGAG RPQRCLPVFE NAAFGRLAQA
60 70 80 90 100
SHTCGSPPED FCPHVGAAGA GAHCQRCDAA DPQRHHNASY LTDFHSQDES
110 120 130 140 150
TWWQSPSMAF GVQYPTSVNI TLRLGKAYEI TYVRLKFHTS RPESFAIYKR
160 170 180 190 200
SRADGPWEPY QFYSASCQKT YGRPEGQCLR PGEDERVAFC TSEFSDISPL
210 220 230 240 250
SGGNVAFSTL EGRPSAYNFE ESPGLQEWVT STELLISLDR LNTFGDDIFK
260 270 280 290 300
DPKVLQSYYY AVSDFSVGGR CKCNGHASEC GPDVAGQLAC RCQHNTTGTD
310 320 330 340 350
CERCLPFFQD RPWARGTAEA AHECLPCNCS GRSEECTFDR ELFRSTGHGG
360 370 380 390 400
RCHHCRDHTA GPHCERCQEN FYHWDPRMPC QPCDCQSAGS LHLQCDDTGT
410 420 430 440 450
CACKPTVTGW KCDRCLPGFH SLSEGGCRPC TCNPAGSLDT CDPRSGRCPC
460 470 480 490 500
KENVEGNLCD RCRPGTFNLQ PHNPSSRSCR SRASRVTSPR SAPTNRTWRP
510 520
FCTACPRTVP AGSEGCPDPR HTLPHLLFT
Length:529
Mass (Da):57,969
Last modified:October 1, 2002 - v1
Checksum:i281138B9D63FAF4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075536 mRNA Translation: BAC11679.1
RefSeqiNP_006050.3, NM_006059.3
UniGeneiHs.201805

Genome annotation databases

GeneIDi10319
KEGGihsa:10319

Similar proteinsi

Entry informationi

Entry nameiQ8N2D6_HUMAN
AccessioniPrimary (citable) accession number: Q8N2D6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 25, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health