Q8N238 (Q8N238_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ34962 fis, clone NTONG2003897, highly similar to Homo sapiens acetyl-CoA synthetase mRNA EMBL BAC03849.1
Organism	Homo sapiens (Human) EMBL BAC03849.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	714 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Molecular function	AMP binding Inferred from electronic annotation. Source: InterPro acetate-CoA ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8N238 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 820C68AD0BF0F4AE	FASTA	714	80,035
	10 20 30 40 50 60 MGLPEERVRS GSGSRGQEEA GAGGRARSWS PPPEVSRSAH VPSLQRYREL HRRSVEEPRE 70 80 90 100 110 120 FWGDIAKEFY WKTPCPGPLL RYNFDVTKGK IFIEWMKGAT TNICYNVLDR NVHEKKLGDK 130 140 150 160 170 180 VAFYWEGNEP GETTQITYHQ LLVQVCQFSN VLRKQGIQKG DRVAIYMPMI PELVVAMLAC 190 200 210 220 230 240 ARIGALHSIV FAGFSSESLC ERILDSSCSL LITTDAFYRG EKLVNLKELA DEALQKCQEK 250 260 270 280 290 300 GFPVRCCIVV KHLGRAELGM GDSTSQSPPI KRSCPDVQGK LKEKSKRVQP QISWNQGIDL 310 320 330 340 350 360 WWHELMQEAG DECEPEWCDA EDPLFILYTS GSTGKPKGVV HTVGGYMLYV ATTFKYVFDF 370 380 390 400 410 420 HAEDVFWCTA DIGWITGHSY VTYGPLANGA TSVLFEGIPT YPDVNRLWSI VDKYKVTKFY 430 440 450 460 470 480 TAPTAIRLLM KFGDEPVTKH SRASLQVLGT VGEPINPEAW LWYHRVVGAQ RCPIVDTFWQ 490 500 510 520 530 540 TETGGHMLTP LPGATPMKPG SATFPFFGVA PAILNESGEE LEGEAEGYLV FKQPWPGIMR 550 560 570 580 590 600 TVYGNHERFE TTYFKKFPGY YVTGDGCQRD QDGYYWITGR IDDMLNVSGH LLSTAEVESA 610 620 630 640 650 660 LVEHEAVAEA AVVGHPHPVK GECLYCFVTL CDGHTFSPKL TEELKKQIRE KIGPIATPDY 670 680 690 700 710 IQNAPGLPKT RSGKIMRRVL RKIAQNDHDL GDLSTVADPS VISHLFSHRC LTIQ

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Tongue EMBL BAC03849.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK092281 mRNA. Translation: BAC03849.1.
IPI	IPI00549564.
RefSeq	NP_001070020.2. NM_001076552.2.
UniGene	Hs.517034.
3D structure databases
HSSP	HSSP built from PDB template 1PG4 based on UniProtKB Q8ZKF6.
ProteinModelPortal	Q8N238.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8N238.
Proteomic databases
PRIDE	Q8N238.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	55902.
KEGG	hsa:55902.
Organism-specific databases
CTD	55902.
Phylogenomic databases
GeneTree	ENSGT00550000074278.
HOVERGEN	HBG014401.
Gene expression databases
ArrayExpress	Q8N238.
Family and domain databases
InterPro	IPR011904. Ac_CoA_lig. IPR024597. Acyl-CoA_synth_DUF3448. IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
KO	K01895.
PANTHER	PTHR24095:SF42. PTHR24095:SF42. 1 hit.
Pfam	PF00501. AMP-binding. 1 hit. PF11930. DUF3448. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8N238_HUMAN

Accession

Primary (citable) accession number: Q8N238

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.