Q8N1N2 (CR026_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C18orf26

Gene names

Name:

C18orf26

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Polymorphism
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 210	210	Uncharacterized protein C18orf26		PRO_0000079315
Regions
	Transmembrane	114 – 134	21	Helical; Potential
	Compositional bias	172 – 207	36	Thr-rich
Natural variations
	Natural variant	38	1	V → A. Corresponds to variant rs35428499 [ dbSNP | Ensembl ].		VAR_033751
	Natural variant	189	1	T → P. Corresponds to variant rs9947055 [ dbSNP | Ensembl ].		VAR_033752

Sequences

	Sequence		Length	Mass (Da)
	Q8N1N2 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: E94FE6D340D3CF79	FASTA	210	22,529
	10 20 30 40 50 60 MVADIKGNEQ IEKYSWREAC DTGSSRMDRK HGKYILNVEH SENQPPITHP NDQEAHSSIC 70 80 90 100 110 120 WCLPSNDITS DVSPNLTGVC VNPGILAHSR CLQSESCNTQ VKEYCRNDWS MWKVFLACLL 130 140 150 160 170 180 ACVIMTAIGV LIICLVNNKG SANSSIVIQL STNDGECVTV KPGTPSPACP PTMTTTSTVP 190 200 210 ASTATESTTS TATAATTSTE PITVAPTDHL

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Tongue.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK096425 mRNA. Translation: BAC04784.1.
IPI	IPI00166204.
RefSeq	NP_775900.1. NM_173629.1.
UniGene	Hs.376146.
3D structure databases
ProteinModelPortal	Q8N1N2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8N1N2.
Polymorphism databases
DMDM	73620598.
Proteomic databases
PRIDE	Q8N1N2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000321600; ENSP00000315265; ENSG00000178690.
GeneID	284254.
KEGG	hsa:284254.
UCSC	uc002lfq.1. human.
Organism-specific databases
CTD	284254.
GeneCards	GC18P052258.
HGNC	HGNC:26808. C18orf26.
HPA	HPA011148.
neXtProt	NX_Q8N1N2.
PharmGKB	PA134946407.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG17981.
GeneTree	ENSGT00400000022381.
InParanoid	Q8N1N2.
OMA	PGVLAHS.
OrthoDB	EOG42RD91.
PhylomeDB	Q8N1N2.
Gene expression databases
ArrayExpress	Q8N1N2.
Bgee	Q8N1N2.
CleanEx	HS_C18orf26.
Genevestigator	Q8N1N2.
Family and domain databases
ProtoNet	Search...
Other
NextBio	94661.

Entry information

Entry name

CR026_HUMAN

Accession

Primary (citable) accession number: Q8N1N2

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.