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Protein
Submitted name:

cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27442

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8N1K8
PRIDEiQ8N1K8

Expressioni

Gene expression databases

GenevisibleiQ8N1K8 HS

Interactioni

Protein-protein interaction databases

IntActiQ8N1K8, 1 interactor
MINTiQ8N1K8

Structurei

3D structure databases

ProteinModelPortaliQ8N1K8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 219PHInterPro annotationAdd BLAST107
Domaini247 – 338GEDInterPro annotationAdd BLAST92

Phylogenomic databases

eggNOGiKOG0446 Eukaryota
COG0699 LUCA
HOGENOMiHOG000161069
HOVERGENiHBG107833

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR027188 DNM2
IPR000375 Dynamin_central
IPR022812 Dynamin_SF
IPR003130 GED
IPR020850 GED_dom
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR11566 PTHR11566, 1 hit
PTHR11566:SF23 PTHR11566:SF23, 1 hit
PfamiView protein in Pfam
PF01031 Dynamin_M, 1 hit
PF02212 GED, 1 hit
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00302 GED, 1 hit
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS51388 GED, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q8N1K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFEAIVKKQ IVKLKEPSLK CVDLVVSELA TVIKKCAEKL SSYPRLREET
60 70 80 90 100
ERIVTTYIRE REGRTKDQIL LLIDIEQSYI NTNHEDFIGF ANAQQRSTQL
110 120 130 140 150
NKKRAIPNQG EILVIRRGWL TINNISLMKG GSKEYWFVLT AESLSWYKDE
160 170 180 190 200
EEKEKKYMLP LDNLKIRDVE KGFMSNKHVF AIFNTEQRNV YKDLRQIELA
210 220 230 240 250
CDSQEDVDSW KASFLRAGVY PEKDQAENED GAQENTFSMD PQLERQVETI
260 270 280 290 300
RNLVDSYVAI INKSIRDLMP KTIMHLMINN TKAFIHHELL AYLYSSADQS
310 320 330 340 350
SLMEESADQA QRRDDMLRMY HALKEALNII GDISTSTVST PVPPPVDDTW
360 370 380 390 400
LQSASSHSPT PQRRPVSSIH PPGRPPAVRG PTPGPPLIPV PVGAAASFSA
410 420 430 440 450
PPIPSRPGPQ SVFANSDLFP APPQIPSRPV RIPPGIPPGV PSRRPPAAPS
460
RPTIIRPAEP SLLD
Length:464
Mass (Da):52,199
Last modified:October 1, 2002 - v1
Checksum:iA56592DDAD9B7368
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097875 mRNA Translation: BAC05190.1
RefSeqiNP_001005361.1, NM_001005361.2
UniGeneiHs.211463

Genome annotation databases

GeneIDi1785

Similar proteinsi

Entry informationi

Entry nameiQ8N1K8_HUMAN
AccessioniPrimary (citable) accession number: Q8N1K8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health