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Protein
Submitted name:

cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27442.

PTM / Processingi

Proteomic databases

PRIDEiQ8N1K8.

Expressioni

Gene expression databases

BgeeiQ8N1K8.
GenevisibleiQ8N1K8. HS.

Interactioni

Protein-protein interaction databases

MINTiMINT-1379377.
STRINGi9606.ENSP00000347890.

Structurei

3D structure databases

ProteinModelPortaliQ8N1K8.
SMRiQ8N1K8. Positions 114-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains GED domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000161069.
HOVERGENiHBG107833.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR027188. DNM2.
IPR000375. Dynamin_central.
IPR022812. Dynamin_SF.
IPR003130. GED.
IPR020850. GTPase_effector_domain_GED.
IPR011993. PH-like_dom.
IPR001849. PH_domain.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PTHR11566:SF23. PTHR11566:SF23. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF02212. GED. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00302. GED. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
PROSITEiPS51388. GED. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8N1K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFEAIVKKQ IVKLKEPSLK CVDLVVSELA TVIKKCAEKL SSYPRLREET
60 70 80 90 100
ERIVTTYIRE REGRTKDQIL LLIDIEQSYI NTNHEDFIGF ANAQQRSTQL
110 120 130 140 150
NKKRAIPNQG EILVIRRGWL TINNISLMKG GSKEYWFVLT AESLSWYKDE
160 170 180 190 200
EEKEKKYMLP LDNLKIRDVE KGFMSNKHVF AIFNTEQRNV YKDLRQIELA
210 220 230 240 250
CDSQEDVDSW KASFLRAGVY PEKDQAENED GAQENTFSMD PQLERQVETI
260 270 280 290 300
RNLVDSYVAI INKSIRDLMP KTIMHLMINN TKAFIHHELL AYLYSSADQS
310 320 330 340 350
SLMEESADQA QRRDDMLRMY HALKEALNII GDISTSTVST PVPPPVDDTW
360 370 380 390 400
LQSASSHSPT PQRRPVSSIH PPGRPPAVRG PTPGPPLIPV PVGAAASFSA
410 420 430 440 450
PPIPSRPGPQ SVFANSDLFP APPQIPSRPV RIPPGIPPGV PSRRPPAAPS
460
RPTIIRPAEP SLLD
Length:464
Mass (Da):52,199
Last modified:October 1, 2002 - v1
Checksum:iA56592DDAD9B7368
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097875 mRNA. Translation: BAC05190.1.
RefSeqiNP_001005361.1. NM_001005361.2.
UniGeneiHs.211463.

Genome annotation databases

GeneIDi1785.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097875 mRNA. Translation: BAC05190.1.
RefSeqiNP_001005361.1. NM_001005361.2.
UniGeneiHs.211463.

3D structure databases

ProteinModelPortaliQ8N1K8.
SMRiQ8N1K8. Positions 114-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1379377.
STRINGi9606.ENSP00000347890.

Proteomic databases

PRIDEiQ8N1K8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1785.

Organism-specific databases

CTDi1785.
PharmGKBiPA27442.

Phylogenomic databases

HOGENOMiHOG000161069.
HOVERGENiHBG107833.

Miscellaneous databases

GenomeRNAii1785.
NextBioi7257.

Gene expression databases

BgeeiQ8N1K8.
GenevisibleiQ8N1K8. HS.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR027188. DNM2.
IPR000375. Dynamin_central.
IPR022812. Dynamin_SF.
IPR003130. GED.
IPR020850. GTPase_effector_domain_GED.
IPR011993. PH-like_dom.
IPR001849. PH_domain.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PTHR11566:SF23. PTHR11566:SF23. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF02212. GED. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00302. GED. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
PROSITEiPS51388. GED. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThymusImported.

Entry informationi

Entry nameiQ8N1K8_HUMAN
AccessioniPrimary (citable) accession number: Q8N1K8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 22, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.