Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8N1K8

- Q8N1K8_HUMAN

UniProt

Q8N1K8 - Q8N1K8_HUMAN

Protein
Submitted name:

cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: InterPro

    GO - Biological processi

    1. endocytosis Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. microtubule Source: InterPro

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA27442.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8N1K8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8N1K8.
    BgeeiQ8N1K8.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1379377.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8N1K8.
    SMRiQ8N1K8. Positions 114-219.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PH domain.UniRule annotation
    Contains GED domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000161069.
    HOVERGENiHBG107833.
    KOiK01528.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR027188. DNM2.
    IPR000375. Dynamin_central.
    IPR022812. Dynamin_SF.
    IPR003130. GED.
    IPR020850. GTPase_effector_domain_GED.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view]
    PANTHERiPTHR11566. PTHR11566. 1 hit.
    PTHR11566:SF23. PTHR11566:SF23. 1 hit.
    PfamiPF01031. Dynamin_M. 1 hit.
    PF02212. GED. 1 hit.
    PF00169. PH. 1 hit.
    [Graphical view]
    SMARTiSM00302. GED. 1 hit.
    SM00233. PH. 1 hit.
    [Graphical view]
    PROSITEiPS51388. GED. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8N1K8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAFEAIVKKQ IVKLKEPSLK CVDLVVSELA TVIKKCAEKL SSYPRLREET    50
    ERIVTTYIRE REGRTKDQIL LLIDIEQSYI NTNHEDFIGF ANAQQRSTQL 100
    NKKRAIPNQG EILVIRRGWL TINNISLMKG GSKEYWFVLT AESLSWYKDE 150
    EEKEKKYMLP LDNLKIRDVE KGFMSNKHVF AIFNTEQRNV YKDLRQIELA 200
    CDSQEDVDSW KASFLRAGVY PEKDQAENED GAQENTFSMD PQLERQVETI 250
    RNLVDSYVAI INKSIRDLMP KTIMHLMINN TKAFIHHELL AYLYSSADQS 300
    SLMEESADQA QRRDDMLRMY HALKEALNII GDISTSTVST PVPPPVDDTW 350
    LQSASSHSPT PQRRPVSSIH PPGRPPAVRG PTPGPPLIPV PVGAAASFSA 400
    PPIPSRPGPQ SVFANSDLFP APPQIPSRPV RIPPGIPPGV PSRRPPAAPS 450
    RPTIIRPAEP SLLD 464
    Length:464
    Mass (Da):52,199
    Last modified:October 1, 2002 - v1
    Checksum:iA56592DDAD9B7368
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK097875 mRNA. Translation: BAC05190.1.
    RefSeqiNP_001005361.1. NM_001005361.2.
    UniGeneiHs.211463.

    Genome annotation databases

    GeneIDi1785.
    KEGGihsa:1785.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK097875 mRNA. Translation: BAC05190.1 .
    RefSeqi NP_001005361.1. NM_001005361.2.
    UniGenei Hs.211463.

    3D structure databases

    ProteinModelPortali Q8N1K8.
    SMRi Q8N1K8. Positions 114-219.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1379377.

    Proteomic databases

    PRIDEi Q8N1K8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1785.
    KEGGi hsa:1785.

    Organism-specific databases

    CTDi 1785.
    PharmGKBi PA27442.

    Phylogenomic databases

    HOGENOMi HOG000161069.
    HOVERGENi HBG107833.
    KOi K01528.

    Miscellaneous databases

    GenomeRNAii 1785.
    NextBioi 7257.

    Gene expression databases

    ArrayExpressi Q8N1K8.
    Bgeei Q8N1K8.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR027188. DNM2.
    IPR000375. Dynamin_central.
    IPR022812. Dynamin_SF.
    IPR003130. GED.
    IPR020850. GTPase_effector_domain_GED.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view ]
    PANTHERi PTHR11566. PTHR11566. 1 hit.
    PTHR11566:SF23. PTHR11566:SF23. 1 hit.
    Pfami PF01031. Dynamin_M. 1 hit.
    PF02212. GED. 1 hit.
    PF00169. PH. 1 hit.
    [Graphical view ]
    SMARTi SM00302. GED. 1 hit.
    SM00233. PH. 1 hit.
    [Graphical view ]
    PROSITEi PS51388. GED. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: ThymusImported.

    Entry informationi

    Entry nameiQ8N1K8_HUMAN
    AccessioniPrimary (citable) accession number: Q8N1K8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.