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Q8N1K8 (Q8N1K8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL BAC05190.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length464 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. RuleBase RU003350

Contains GED domain. SAAS SAAS003130

Ontologies

Gene Ontology (GO)
   Biological_processendocytosis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmicrotubule

Inferred from electronic annotation. Source: InterPro

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: InterPro

GTPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q8N1K8 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: A56592DDAD9B7368

FASTA46452,199
        10         20         30         40         50         60 
MAFEAIVKKQ IVKLKEPSLK CVDLVVSELA TVIKKCAEKL SSYPRLREET ERIVTTYIRE 

        70         80         90        100        110        120 
REGRTKDQIL LLIDIEQSYI NTNHEDFIGF ANAQQRSTQL NKKRAIPNQG EILVIRRGWL 

       130        140        150        160        170        180 
TINNISLMKG GSKEYWFVLT AESLSWYKDE EEKEKKYMLP LDNLKIRDVE KGFMSNKHVF 

       190        200        210        220        230        240 
AIFNTEQRNV YKDLRQIELA CDSQEDVDSW KASFLRAGVY PEKDQAENED GAQENTFSMD 

       250        260        270        280        290        300 
PQLERQVETI RNLVDSYVAI INKSIRDLMP KTIMHLMINN TKAFIHHELL AYLYSSADQS 

       310        320        330        340        350        360 
SLMEESADQA QRRDDMLRMY HALKEALNII GDISTSTVST PVPPPVDDTW LQSASSHSPT 

       370        380        390        400        410        420 
PQRRPVSSIH PPGRPPAVRG PTPGPPLIPV PVGAAASFSA PPIPSRPGPQ SVFANSDLFP 

       430        440        450        460 
APPQIPSRPV RIPPGIPPGV PSRRPPAAPS RPTIIRPAEP SLLD 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Thymus EMBL BAC05190.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK097875 mRNA. Translation: BAC05190.1.
RefSeqNP_001005361.1. NM_001005361.2.
UniGeneHs.211463.

3D structure databases

ProteinModelPortalQ8N1K8.
SMRQ8N1K8. Positions 114-219.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-1379377.

Proteomic databases

PRIDEQ8N1K8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1785.
KEGGhsa:1785.

Organism-specific databases

CTD1785.
PharmGKBPA27442.

Phylogenomic databases

HOGENOMHOG000161069.
HOVERGENHBG107833.
KOK01528.

Gene expression databases

ArrayExpressQ8N1K8.
BgeeQ8N1K8.

Family and domain databases

Gene3D2.30.29.30. 1 hit.
InterProIPR027188. DNM2.
IPR000375. Dynamin_central.
IPR022812. Dynamin_SF.
IPR003130. GED.
IPR020850. GTPase_effector_domain_GED.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
[Graphical view]
PANTHERPTHR11566. PTHR11566. 1 hit.
PTHR11566:SF23. PTHR11566:SF23. 1 hit.
PfamPF01031. Dynamin_M. 1 hit.
PF02212. GED. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTSM00302. GED. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
PROSITEPS51388. GED. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi1785.
NextBio7257.

Entry information

Entry nameQ8N1K8_HUMAN
AccessionPrimary (citable) accession number: Q8N1K8
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.