##gff-version 3
Q8N142	UniProtKB	Chain	1	457	.	.	.	ID=PRO_0000095132;Note=Adenylosuccinate synthetase isozyme 1	
Q8N142	UniProtKB	Region	1	21	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8N142	UniProtKB	Active site	43	43	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Active site	71	71	.	.	.	Note=Proton donor;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	42	48	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	43	46	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	43	43	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	43	43	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	68	71	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	70	72	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	70	70	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	163	163	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	177	177	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	256	256	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	271	271	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	331	337	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	335	335	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	337	337	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	363	365	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Binding site	445	448	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03126	
Q8N142	UniProtKB	Alternative sequence	1	64	.	.	.	ID=VSP_008421;Note=In isoform 2. MSGTRASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQ->MVGRSCGVATQRQGGGQRPTNLALTLSSSPAHSTALPWLPPRSLQLLSGHSVPAQPTPHLPSACGGPTRVTLGEERAWRSHGSNAGGHTCLPRRTAGAGSLTPGGER;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q8N142	UniProtKB	Natural variant	261	261	.	.	.	ID=VAR_076998;Note=In MPD5%3B decreased protein abundance%3B decreased stability%3B decreased adenylosuccinate synthase activity. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26506222;Dbxref=dbSNP:rs140614802,PMID:26506222