Unreviewed, UniProtKB/TrEMBL Q8MZH4 (Q8MZH4_DROME)

Names and origin

Protein names

Submitted name:
    Start1, isoform B EMBL AAS64770.1
Submitted name:
    LD23890p EMBL AAM27512.1

Gene names

Name:	Start1 FlyBase FBgn0035028
ORF Names:	CG3522 EMBL AAM27512.1 FlyBase FBgn0035028, Dmel_CG3522 EMBL AAS64770.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAM27512.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	545 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 START domain. Spearmint SPM002913

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	steroid biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cholesterol binding Inferred from electronic annotation. Source: InterPro cholesterol transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MZH4-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 5F6EAF98AC917160	FASTA	545	61,430
	10 20 30 40 50 60 MSNMDPSDVR STAQLILANA RQGNSAYNMQ YDMSRAHSIN LITEDFLAGY MQDGRMSVVR 70 80 90 100 110 120 RFFCLFVTFD LVFVSLLWLI CIVINGDNIF TAFHKQIVEY TIYKSLFDVV AVAICRFLVL 130 140 150 160 170 180 IFFYAILYIN HWSIIALSTS GSCLFLISKV FVFDWLDSKQ QVFEVILIIT SFILAWGEAW 190 200 210 220 230 240 FLDCRVIPQE RHAQHYFRTM TSNDRTPMEQ PAILIEQERP PQSVTDFYSL MDTARHSDEE 250 260 270 280 290 300 DELDDEYTQM GLDCLRKAYE IIESSDWKVE KVNQKGDTIH STQRDKIGKI YKLTARIKYP 310 320 330 340 350 360 AKALMEDLFY RIEDCPKWNP ALLESKIVRK INSYTDITYQ VSVGGGGGMV KSRDFVNLRS 370 380 390 400 410 420 CRLFYNGQIC DDDETAQLSS DDGNSSLNRS CEGSVSTISD GDSNTPLLPS SVSSCKATFP 430 440 450 460 470 480 TSSKGAAMPF DTLGNSLGAK SLGPIVNFDE EPPPLDQDEF EDAKDKVDGE ANNMTKPNVP 490 500 510 520 530 540 SVGKTKDRVW VTSAVSVQYA AVPPSPKYTS RLTLQFSEGR TLSVGLRFVK SLENRIAALW SGCFA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM27512.1.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY102683 mRNA. Translation: AAM27512.1. AE013599 Genomic DNA. Translation: AAS64770.1.
RefSeq	NP_995939.1.
UniGene	Dm.11675
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q8MZH4.
Genome annotation databases
Ensembl	FBgn0035028. Drosophila melanogaster. [Contig view]
GeneID	37927.
Organism-specific databases
FlyBase	FBgn0035028. Start1.
Gene expression databases
ArrayExpress	Q8MZH4.
Family and domain databases
InterPro	IPR019498. Cholesterol-capturing_domain. IPR000799. StAR. IPR002913. START_lipid_bd. [Graphical view]
Pfam	PF10457. MENTAL. 1 hit. PF01852. START. 1 hit. [Graphical view]
PRINTS	PR00978. STARPROTEIN.
PROSITE	PS50848. START. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	806088.

Entry information

Entry name

Q8MZH4_DROME

Accession

Primary (citable) accession number: Q8MZH4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)