Reviewed,
UniProtKB/Swiss-Prot Q8MU95 (BGBP_PLOIN)
Last modified
June 16, 2009.
Version 26.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Beta-1,3-glucan-binding protein Short name=BGBP Alternative name(s): Beta-1,3-glucan recognition protein Short name=BetaGRP |
| Organism | Plodia interpunctella (Indianmeal moth) |
| Taxonomic identifier | 58824 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Lepidoptera › Glossata › Ditrysia › Pyraloidea › Pyralidae › Phycitinae › Plodia |
Protein attributes
| Sequence length | 488 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan, causing aggregation of invading micro-organisms and activation of the phenoloxidase cascade. Ref.1 |
| Subunit structure | Monomer. Ref.1 |
| Subcellular location | |
| Tissue specificity | Fat body and hemolymph. Ref.1 |
| Developmental stage | Expression is maintained at a moderate level throughout development from embryo to adult. Ref.1 |
| Post-translational modification | The N-terminus is blocked. Ref.1 |
| Sequence similarities | Belongs to the insect beta-1,3-glucan binding protein family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Immune response Innate immunity |
| Cellular component | Secreted |
| Domain | Signal |
| PTM | Glycoprotein |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | innate immune response Inferred from electronic annotation. Source: UniProtKB-KW regulation of innate immune response Ref.1Inferred from direct assay. Source: UniProtKB |
| Cellular component | extracellular region Ref.1 Inferred from direct assay. Source: UniProtKB |
| Molecular function | bacterial binding Ref.1 Inferred from direct assay. Source: UniProtKB |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 17 | 17 | Potential | ||||||
| Chain | 18 – 488 | 471 | Beta-1,3-glucan-binding protein | PRO_0000002823 | |||||
Amino acid modifications | |||||||||
| Glycosylation | 373 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 453 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| [1] | "cDNA cloning, purification, properties and function of a beta-1,3-glucan recognition protein from a pyralid moth, Plodia interpunctella." Fabrick J.A., Baker J.E., Kanost M.R. Insect Biochem. Mol. Biol. 33:579-594(2003) [PubMed: 12770576] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 21-30, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Strain: HD198. Tissue: Larva and Larval plasma. |
Cross-references
Sequence databases | |
|---|---|
| AF532603 mRNA. Translation: AAM95970.1. | |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | CBM39. Carbohydrate-Binding Module Family 39. GH16. Glycoside Hydrolase Family 16. |
Family and domain databases | |
| InterPro | IPR013320. ConA-like_subgrp. [Graphical view] |
| Gene3D | G3DSA:2.60.120.200. ConA_like_subgrp. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | BGBP_PLOIN | ||||||||
| Accession | Primary (citable) accession number: Q8MU95 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||

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