Unreviewed, UniProtKB/TrEMBL Q8MST5 (Q8MST5_DROME)

Names and origin

Protein names

Submitted name:
    LP10436p EMBL AAM49980.1

Gene names

Name:	betaTub97EF FlyBase FBgn0003890
Synonyms:	beta-Tub97EF FlyBase FBgn0003890
ORF Names:	CG4869 EMBL AAM49980.1 FlyBase FBgn0003890

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAM49980.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain By similarity. RuleBase RU003505V0 Spearmint SPM003008
Subunit structure	Dimer of alpha and beta chains By similarity. RuleBase RU003505V0 Spearmint SPM003008
Sequence similarities	Belongs to the tubulin family. RuleBase RU000352V1

Ontologies

Keywords
Cellular component	Microtubule RuleBase RU000352V1 Spearmint SPM003008
Ligand	GTP-binding RuleBase RU000351V1 Spearmint SPM013838 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	microtubule-based movement Inferred from electronic annotation. Source: InterPro protein polymerization Inferred from electronic annotation. Source: InterPro
Cellular component	microtubule Inferred from electronic annotation. Source: InterPro protein complex Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MST5-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 12940FF0A84446E0	FASTA	457	51,252
	10 20 30 40 50 60 MREIVHLQAG QCGNQIGSKF WEIISDEHGI DPNGYYHGES ALQHERIDVY YNEASSGKYV 70 80 90 100 110 120 PRAVLIDLEP GTMDSVRQSP VGQLFRPDNF VYGQSGAGNN WAKGHYTEGA ELIDSVLEVL 130 140 150 160 170 180 RKESEGCDCL QGFQLAHSLG GGTGSGLGTL LISKIREEYP DRIMNSFSVV PSPKVSDTVV 190 200 210 220 230 240 EPYNATLSIH QLVENTDETF CIDNEALYDI CFRTLKLSSP TYGDLNHLVS VTMSGVTTCL 250 260 270 280 290 300 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTAKGSQQ YRALTVAELT QQMFDAKNMM 310 320 330 340 350 360 TACDPRHGRY LTVACIFRGP MSMKEVDTQM YNVQSKNSSY FVEWIPNNVK VAVCDIPPRG 370 380 390 400 410 420 LKMSATFIGN STAIQEIFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLIS 430 440 450 EYQQYQEATA DDEVEFDDEQ AEQEGYESEV LQNGNGE

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM49980.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY118611 mRNA. Translation: AAM49980.1.
3D structure databases
HSSP	HSSP built from PDB template 1FFX based on UniProtKB P02554.
SMR	Q8MST5. Positions 2-427.
ModBase	Search...
Proteomic databases
PRIDE	Q8MST5.
Genome annotation databases
Ensembl	FBgn0003890. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0003890. betaTub97EF.
Gene expression databases
ArrayExpress	Q8MST5.
Family and domain databases
InterPro	IPR013838. Beta-tubulin_BS. IPR002453. Beta_tubulin. IPR000217. Tubulin. IPR018316. Tubulin/FtsZ_2-layer-sand-dom. IPR017975. Tubulin_CS. IPR003008. Tubulin_FtsZ_GTPase. [Graphical view]
Gene3D	G3DSA:3.30.1330.20. Tubulin/FtsZ_2-layer-sand-dom. 1 hit. G3DSA:3.40.50.1440. Tubulin_FtsZ. 1 hit.
PANTHER	PTHR11588:SF9. Beta_tubulin. 1 hit. PTHR11588. Tubulin. 1 hit.
Pfam	PF00091. Tubulin. 1 hit. PF03953. Tubulin_C. 1 hit. [Graphical view]
PRINTS	PR01163. BETATUBULIN. PR01161. TUBULIN.
PROSITE	PS00227. TUBULIN. 1 hit. PS00228. TUBULIN_B_AUTOREG. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8MST5_DROME

Accession

Primary (citable) accession number: Q8MST5

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	July 7, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)