Q8MSR0 (Q8MSR0_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Transporter RuleBase RU003732

Gene names

Name:	bdg FlyBase FBgn0034049
ORF Names:	CG8291 EMBL AAM50021.1 FlyBase FBgn0034049

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM50021.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1331 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the sodium:neurotransmitter symporter (SNF) family. RuleBase RU003732

Ontologies

Keywords
Biological process	Symport RuleBase RU003732 SAAS SAAS000175 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000175
Gene Ontology (GO)
Biological process	R3/R4 cell fate commitment Inferred from mutant phenotype. Source: FlyBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	neurotransmitter:sodium symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MSR0 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: EF22DEEB89DFD9FD	FASTA	1,331	146,590
	10 20 30 40 50 60 MSSKEQQAAG RDFKRNSNAY SSLPPTGTGA GCSGAALGSG TGTGKRARSK QHQLEHEQFG 70 80 90 100 110 120 LSNSLSSESI RQACAYYDDE LSDEDLIEIQ QTPQAFHQQT KQPLQLQPIS FRLGDELGDE 130 140 150 160 170 180 RSAFCGSQEM QQVPLSTPIK QAAETDEALC VLSELDAILD VHDVSQLNGT CSSGSVNSGS 190 200 210 220 230 240 DDDKVEDYLM DLDNYLEEMD NALNREDSLI IIDGHTSLKR EPRTRTLPLS RKKKSSKKKS 250 260 270 280 290 300 EDQEAAQGDF QREHQLRKTF SCSLRPTSQI ASSSGSLETS TEPVMDVWRR QSMRRALEQE 310 320 330 340 350 360 DTKATVAMER EEDDIPTLLV ELPPRRDAEM RRCFSQGDCQ ASVAPTGGSQ MLTEAHIFDN 370 380 390 400 410 420 LLQTNARASS EEPRPRQYGR RLEGPPTPVR SLILAQSRPQ SAPTRVQMRE PQLQDTPTHP 430 440 450 460 470 480 IMSTCSELSS ARSSRMPSPV SLPSDSSSSG SSSAEHDQEP DPVQTTTMCS ASSTTPLEPL 490 500 510 520 530 540 HQLQLLLREK CGFNSQWPHA GSRTLALIGC TLGVFNMCRF AVLTINFGGN FLLQFLLLSV 550 560 570 580 590 600 IFGIPLLWLQ MCLGAKIRAG PVSMWKISPI CAGVGIALVM QQCFLALYST VSLAWILVYL 610 620 630 640 650 660 RDVFPTAARS GYRWQEMAFP YRYDASNATG NLTQTVAEYF NVVVLQRLHL ANHPDASGIR 670 680 690 700 710 720 FHVNDRQLAF YLALIWAAVF LILCKGLKSL GKLAYIIYTL PLVALAVVTA KFVYVVDPSR 730 740 750 760 770 780 IQNIFAASDF DDFLVNSNSW TAATQETFLT WGLLGASVIA ITSRSHTNAN KAALRRDAIL 790 800 810 820 830 840 LVLFTLIGLG LMALLALCCA QILWQHGYVY VPGSFENPDC YTSIYSLQSN TNPYLLSYPR 850 860 870 880 890 900 SLIPHYSSFI GETYRRNRTM IHVESGFQAL RFISEIFPAV LSLASDSISW VWAAVAFATF 910 920 930 940 950 960 AGFGLAQLCV MWKPISSALG NSTSSVLLSC VTGLLLSIPF ATEMGISILY YVDFLLGGSW 970 980 990 1000 1010 1020 FIPIIWTAQI FGVFLIRGRP YNGDDLVNDL RLCGSMSAFL ALSWNVLLPI GLITLSVVDY 1030 1040 1050 1060 1070 1080 KASLSNQFYY WRGKSYFTYW SRKMGSLIQI GVLLVIPVTA IIQIYRYLAH GPPDILERIQ 1090 1100 1110 1120 1130 1140 LLYRPPEEGE EPRRPSARQT ASQSRRNALG QTTEGGQHDA QNDAPPKYTP PPSYTTATGA 1150 1160 1170 1180 1190 1200 RLAKLLRQSI RRSVRRVLGD SSRTRPVLSL DAESASPAAP PDYLTILTNP AGSSFNADPS 1210 1220 1230 1240 1250 1260 PASSSSPESI EIDQRPVGYA QRSQSLGRKL HRSGASTLER RPYTAEDVVT ILRSSVRHRQ 1270 1280 1290 1300 1310 1320 SQGGGNLVTA STLPRPPTAA MSTHLEDASF RSIENLVLNA EPPDRTPGVE LELELEAGQA 1330 EECARNNTSV I

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY118652 mRNA. Translation: AAM50021.1.
3D structure databases
ProteinModelPortal	Q8MSR0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8MSR0.
Proteomic databases
PRIDE	Q8MSR0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	CG8291-RA. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0034049. bdg.
Phylogenomic databases
eggNOG	inNOG06296.
GeneTree	EMGT00050000004580.
InParanoid	Q8MSR0.
Gene expression databases
ArrayExpress	Q8MSR0.
Bgee	Q8MSR0.
Family and domain databases
InterPro	IPR000175. Na/ntran_symport. [Graphical view]
PANTHER	PTHR11616. Na/ntran_symport. 1 hit.
Pfam	PF00209. SNF. 1 hit. [Graphical view]
PRINTS	PR00176. NANEUSMPORT.
PROSITE	PS50267. NA_NEUROTRAN_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8MSR0_DROME

Accession

Primary (citable) accession number: Q8MSR0

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)