Q8MSA6 (Q8MSA6_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LD45876p EMBL AAM50828.1

Gene names

Name:	RhoGAP1A EMBL AAM50828.1
ORF Names:	CG40494 FlyBase FBgn0025836

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM50828.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	531 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. SAAS SAAS000198 Contains 1 Rho-GAP domain. SAAS SAAS000198

Ontologies

Keywords
Molecular function	GTPase activation SAAS SAAS000198
Gene Ontology (GO)
Biological process	signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTPase activator activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MSA6 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 2F199CEE04F7A77D	FASTA	531	60,205
	10 20 30 40 50 60 MVRNSFIVEL VDGHRKLRHL FLFNDVIACA KYKALGRDRI DYELKWFIPL KDVSIYEEAD 70 80 90 100 110 120 PAVELKESSP ANISQVKRNL RSVRDQLAME VANSGSGAFR SGDKYRRKLA DLESQLVLAT 130 140 150 160 170 180 PNLVLRLGNK ANNKTITFFL SSDFERTQWI DSILSLKQKC NLPGANTINS LEVTAFIVAM 190 200 210 220 230 240 QKGMKTEMGS YLMRNTNDES LLVGDLYMGV HGLEGLEQAN DLYICVEVDS YGHYFRKATT 250 260 270 280 290 300 KKICRSQTPL WNESFMLELE GSQNVRILLY EAKERPLLKA KHILKLSLSW LTETTQPKSI 310 320 330 340 350 360 KLTETLELGC SFRFIPGELF RGSTKPGALF GAKMSQVLKR EKRDIPFIIG ACIREVERRG 370 380 390 400 410 420 MLEVGCYRVS GSASDLAKLK KAFESDAYEA EQLLREVDIH SVTGILKTFL RELPEALFTD 430 440 450 460 470 480 QLYPRFFDTF SAFSNNNEST RINELLKVFE ELPQANKASI TSILDHLIRV HEKETDNKMS 490 500 510 520 530 LHNLAMVFGP TLLRPGQTQV KQKDPLAAST VDVMAQAGIL YCFLQARIKK D

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM50828.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY118968 mRNA. Translation: AAM50828.1.
3D structure databases
HSSP	HSSP built from PDB template 1F7C based on UniProtKB Q98935.
ProteinModelPortal	Q8MSA6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8MSA6.
Proteomic databases
PRIDE	Q8MSA6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0025836. RhoGAP1A.
Phylogenomic databases
InParanoid	Q8MSA6.
Gene expression databases
ArrayExpress	Q8MSA6.
Bgee	Q8MSA6.
Family and domain databases
InterPro	IPR000008. C2_Ca-dep. IPR008973. C2_Ca/lipid-bd_dom_CaLB. IPR011993. PH_type. IPR001849. Pleckstrin_homology. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. [Graphical view]
Gene3D	G3DSA:2.30.29.30. PH_type. 2 hits. G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00168. C2. 1 hit. PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00239. C2. 1 hit. SM00233. PH. 1 hit. SM00324. RhoGAP. 1 hit. [Graphical view]
SUPFAM	SSF49562. C2_CaLB. 1 hit. SSF48350. Rho_GAP. 1 hit.
PROSITE	PS50003. PH_DOMAIN. 1 hit. PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8MSA6_DROME

Accession

Primary (citable) accession number: Q8MSA6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)