Q8MRG6 (Q8MRG6_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG7757, isoform B EMBL AAN11640.1

Submitted name:
RE44079p EMBL AAM50294.1

Gene names

ORF Names:

CG7757 EMBL AAM50294.1 FlyBase FBgn0036915, Dmel_CG7757 EMBL AAN11640.1

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM50294.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	528 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nuclear mRNA splicing, via spliceosome Inferred by curator. Source: FlyBase regulation of chromatin silencing Inferred from mutant phenotype. Source: FlyBase
Cellular component	precatalytic spliceosome Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MRG6 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: B590C96A3863CC4A	FASTA	528	60,139
	10 20 30 40 50 60 MMAHAQREIE ERKRALSNLR DKDPLLASVP SIGMPVALAT QALAKKPTPE DSEKARKIAE 70 80 90 100 110 120 LQAQIRAKLT GNLASLIQPT AVAAAAAAAA QAQERPKPLI LDDEGRTVDK SGRTINIPTV 130 140 150 160 170 180 TPTLKANIRA KKREVFQRQT GLGERSESGT SAQEEAIKYF DDRIALKPTV RTKRTLRFHE 190 200 210 220 230 240 PGKFQQLAER MRMKSQLERL QNEISQIARK TGISSATKLA LIAPKQDMPD DVPAMEWWDS 250 260 270 280 290 300 VILTQDLETV DDASGKISIR QTAITNLIEH PTQMKPPNEP LKPVYLPVFL TKKERKKLRR 310 320 330 340 350 360 QNRREAWKEE QEKIRLGLVA PPEPKLRISN LMRVLGSEAV QDPTKMEQHV RDQMAKRQKA 370 380 390 400 410 420 HEDANNARKL TSEQKSEKKQ RKLREDTSCG VHVSVYRIRD LQDNQSKKFK VETNAKQLQM 430 440 450 460 470 480 TGSVVLFRDC CVVVVEGGPK QQKKYRRLML TRIKWEEDNA KGNDGQDVPN SCVLVWEGTS 490 500 510 520 QRRHFGEIKF KIFPMEKMAR EFFQKHQVEH YWDLAYSGAV LEASTDQQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM50294.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY119640 mRNA. Translation: AAM50294.1. AE014296 Genomic DNA. Translation: AAN11640.1.
RefSeq	NP_730463.1. NM_168825.2.
UniGene	Dm.13639.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8MRG6.
Proteomic databases
PRIDE	Q8MRG6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0074892; FBpp0074661; FBgn0036915.
GeneID	40172.
KEGG	dme:Dmel_CG7757.
UCSC	CG7757-RB. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0036915. CG7757.
Phylogenomic databases
eggNOG	inNOG05951.
GeneTree	EMGT00050000015592.
InParanoid	Q8MRG6.
OrthoDB	EOG4FN2ZS.
PhylomeDB	Q8MRG6.
Gene expression databases
ArrayExpress	Q8MRG6.
Bgee	Q8MRG6.
Family and domain databases
InterPro	IPR010541. DUF1115. IPR013881. Pre-mRNA_splic_Prp3. [Graphical view]
KO	K12843.
Pfam	PF06544. DUF1115. 1 hit. PF08572. PRP3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	817396.

Entry information

Entry name

Q8MRG6_DROME

Accession

Primary (citable) accession number: Q8MRG6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)