Unreviewed, UniProtKB/TrEMBL Q8MRA3 (Q8MRA3_DROME)

Names and origin

Protein names

Submitted name:
    Hibris, isoform A EMBL AAF58172.3
Submitted name:
    RE70806p EMBL AAM52025.1

Gene names

Name:	hbs EMBL AAM52025.1 FlyBase FBgn0029082
ORF Names:	CG7449 FlyBase FBgn0029082, Dmel_CG7449 EMBL AAF58172.3

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM52025.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1228 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Cellular component	Membrane Spearmint SPM013162
Domain	Immunoglobulin domain RuleBase RU003326V0 Spearmint SPM013162 Repeat Spearmint SPM013162
PTM	Disulfide bond Spearmint SPM013162
Gene Ontology (GO)
Biological process	myoblast fusion Traceable author statement. Source: FlyBase regulation of striated muscle development Inferred from genetic interaction. Source: FlyBase
Cellular component	membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8MRA3-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 0B8532E0FDFDEEA9	FASTA	1,228	133,632
	10 20 30 40 50 60 MQFWITLTFA VHLATTICHV MAAVTAPTPA AQVAAPPVQK FHLTPHDLQI LEGTDTLLRC 70 80 90 100 110 120 EVSNRAGKVQ WTKDGFALGF SAVIPGFPRY SVLVDAKQNA YNLQIKNATL EDDAEYQCQV 130 140 150 160 170 180 GPAAGNPAIR ANAKLSIVAA PSSIVIEGYA RNARVEVEER QNLTLHCIAE NANPAAEIVW 190 200 210 220 230 240 FQGEVPVSTA PIVTVNQTAP KRFTTSSTLH LQPRAEDDYK EFSCEARHKA LPPDVPMRAQ 250 260 270 280 290 300 VQLSVLYPPG APFFEGYSQG ETLHRGQEVQ IACRSRGGNP PAQLTWYRNG VAISSPQRTS 310 320 330 340 350 360 GRLSENVYKF TAAAEDNGAN LVCEAKNLLA TTPLRAELNL TVLYAPKDVY LSGANQAKVG 370 380 390 400 410 420 DSVQLSCVTA PSNPQARISW SINGRPLDNS TYKTTSSSDG GWVSSSNISL TIDSQSRTFI 430 440 450 460 470 480 AVCHALNTEL TQNVVGSHTV NVLYPPSPPL LTGYNDGDIL ISGSILKLQC SSAGGNPPPT 490 500 510 520 530 540 LQWYKNDKII NAPSKLVDSK ITSELSLLVN ASDNNAIYKC KVQNAAIDIP LFATKTLGVH 550 560 570 580 590 600 FPPETVKISV VPKNLVPGIR AKLICDSSSS NPPAKISWWK DGIPVEGLNL ANRPGLWGGS 610 620 630 640 650 660 VSTLEMYVNI TQDLDGIVYT CQSHNEVLQR SVHETISLDI LYPPKFETPQ STTFVGVEGA 670 680 690 700 710 720 PFHVELLASG NPMVITYTWT KDGLPISSNS LSGQRLISDG PRLNISRLSR NDAGVYICEA 730 740 750 760 770 780 LNSQGTALLE IQVAVEYAPT ITAVSEGRSF VAGEPAVLAC HIQARPLEAA HVRWSRDGYD 790 800 810 820 830 840 LATRTISSFE NGTALLQIAS VERSDIGNFT CIVDNQRGAP AAQNVLLVVQ TAPEIDHSPG 850 860 870 880 890 900 FTRYAARLGV RAQLICRSLA SPQPSFIWRR HGKDLKMQRR NKFKSVERQV DALNFESALL 910 920 930 940 950 960 IENTSPDDYG QYECVVRNSL GQASTTLEFS KPSRPDAPLQ LRVGNVSDTG VDLNWTPGFD 970 980 990 1000 1010 1020 GGMQTYFRLR LKQHGEDKYK YVDAKPGHQN ISLDGLKPGA TYYFSVMAAN EAGGSKFMPD 1030 1040 1050 1060 1070 1080 IKLTLSKGSQ PHSAEYTEKD ELPNVMIIGI TSAAMVLLVL NAALVAWFVI RRQNKSQSEA 1090 1100 1110 1120 1130 1140 EPSNDDVYSK DDSQSVYKAD VQKKAAASTY LVENVDIIQS TAYPPKYQES SMCTPPYPLC 1150 1160 1170 1180 1190 1200 NPDFTRTLPN PKRHSQRNSA TGMIEGMQMR SKDDHMLISN GLYIPSPSPA SSLVIKGSYI 1210 1220 SSPSPAPPAD GSYFNMSDKY MSYPPVTY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM52025.1.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013599 Genomic DNA. Translation: AAF58172.3. AY121698 mRNA. Translation: AAM52025.1.
RefSeq	NP_524702.3.
UniGene	Dm.1858
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8MRA3. 3 interactions.
Proteomic databases
PRIDE	Q8MRA3.
Genome annotation databases
Ensembl	FBgn0029082. Drosophila melanogaster. [Contig view]
GeneID	44129.
KEGG	dme:Dmel_CG7449.
Organism-specific databases
FlyBase	FBgn0029082. hbs.
Gene expression databases
ArrayExpress	Q8MRA3.
Family and domain databases
InterPro	IPR013162. CD80_C2-set. IPR008957. Fibronectin_typ-III-like_fold. IPR003961. FN_III. IPR013151. Ig. IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR003006. Ig/MHC_CS. IPR003599. Ig_sub. IPR003598. Ig_sub2. IPR013106. Ig_V-set. [Graphical view]
Gene3D	G3DSA:2.60.40.30. FN_III-like. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 5 hits.
Pfam	PF08205. C2-set_2. 2 hits. PF00041. fn3. 1 hit. PF00047. ig. 6 hits. PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00060. FN3. 1 hit. SM00409. IG. 4 hits. SM00408. IGc2. 3 hits. [Graphical view]
PROSITE	PS50853. FN3. 1 hit. PS50835. IG_LIKE. 9 hits. PS00290. IG_MHC. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	836838.

Entry information

Entry name

Q8MRA3_DROME

Accession

Primary (citable) accession number: Q8MRA3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	July 7, 2009
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)