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Q8MMF9 (OB57D_DROME) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
General odorant-binding protein 57d
Gene names
Name:Obp57d
ORF Names:CG30150
OrganismDrosophila melanogaster (Fruit fly) [Reference proteome]
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length136 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.

Sequence similarities

Belongs to the PBP/GOBP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential
Chain30 – 136107General odorant-binding protein 57d
PRO_0000012575

Amino acid modifications

Disulfide bond33 ↔ 70 By similarity
Disulfide bond66 ↔ 118 By similarity
Disulfide bond107 ↔ 127 By similarity

Natural variations

Natural variant101V → I in strain: Canton-S, KY02013G20 and KY02073G20. Ref.2
Natural variant281D → E in strain: KY02106G9 and MEL6G59. Ref.2
Natural variant581T → I in strain: Canton-S, KY02010G20, KY02013G20 and KY02073G20. Ref.2
Natural variant871D → E in strain: KY02106G9. Ref.2
Natural variant871D → N in strain: Canton-S, KY02010G20, KY02073G20 and KY02013G20.
Natural variant991A → T in strain: KY02106G9. Ref.2

Experimental info

Sequence conflict801T → A in AAM68388. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q8MMF9 [UniParc].

Last modified March 1, 2005. Version 2.
Checksum: 3073A70754EE7A4F

FASTA13615,747
        10         20         30         40         50         60 
MPEKMSLRLV PHLACIIFIL EIQFRIADSN DPCPHNQGID EDIAESILGD WPANVDLTSV 

        70         80         90        100        110        120 
KRSHKCYVTC ILQYYNIVTT SGEIFLDKYY DTGVIDELAV APKINRCRYE FRMETDYCSR 

       130 
IFAIFNCLRQ EILTKS 

« Hide

References

« Hide 'large scale' references
[1]"The odorant-binding proteins of Drosophila melanogaster: annotation and characterization of a divergent gene family."
Graham L.A., Davies P.L.
Gene 292:43-55(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Canton-S.
[2]"A high frequency null mutant of an odrant-binding protein gene, Obp57e, in Drosophila melanogaster."
Takahashi A., Takano-Shimizu T.
Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Algeria, CA1, KSA2, KY02001G20, KY02002G20, KY02003G20, KY02006G20, KY02010G20, KY02013G20, KY02016G18, KY02070G20, KY02073G20, KY02074G20, KY02101G9, KY02102G9, KY02104G9, KY02106G9, KY02109G9, MEL6G59, MEL7, MEL8 and TaiwanG23.
[3]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[4]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[5]"Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster."
Hekmat-Scafe D.S., Scafe C.R., McKinney A.J., Tanouye M.A.
Genome Res. 12:1357-1369(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF457149 mRNA. Translation: AAM69287.1.
AB189644 Genomic DNA. Translation: BAD83885.1.
AB189645 Genomic DNA. Translation: BAD83887.1.
AB189646 Genomic DNA. Translation: BAD83889.1.
AB189647 Genomic DNA. Translation: BAD83891.1.
AB189648 Genomic DNA. Translation: BAD83893.1.
AB189649 Genomic DNA. Translation: BAD83894.1.
AB189650 Genomic DNA. Translation: BAD83895.1.
AB189651 Genomic DNA. Translation: BAD83896.1.
AB189652 Genomic DNA. Translation: BAD83897.1.
AB189653 Genomic DNA. Translation: BAD83898.1.
AB189654 Genomic DNA. Translation: BAD83899.1.
AB189655 Genomic DNA. Translation: BAD83900.1.
AB189656 Genomic DNA. Translation: BAD83901.1.
AB189657 Genomic DNA. Translation: BAD83902.1.
AB189658 Genomic DNA. Translation: BAD83903.1.
AB189659 Genomic DNA. Translation: BAD83904.1.
AB189660 Genomic DNA. Translation: BAD83905.1.
AB189661 Genomic DNA. Translation: BAD83907.1.
AB189663 Genomic DNA. Translation: BAD83910.1.
AB189664 Genomic DNA. Translation: BAD83911.1.
AB189665 Genomic DNA. Translation: BAD83912.1.
AB189666 Genomic DNA. Translation: BAD83913.1.
AB189667 Genomic DNA. Translation: BAD83915.1.
AE013599 Genomic DNA. Translation: AAM68388.1.
RefSeqNP_725973.1. NM_166397.2.
UniGeneDm.4636.

3D structure databases

ProteinModelPortalQ8MMF9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID246671.
KEGGdme:Dmel_CG30150.

Organism-specific databases

CTD246671.
FlyBaseFBgn0043536. Obp57d.

Phylogenomic databases

eggNOGNOG264569.
InParanoidQ8MMF9.
OrthoDBEOG7NKKN3.

Family and domain databases

Gene3D1.10.238.20. 1 hit.
InterProIPR006170. PBP_GOBP.
IPR023316. PBP_GOBP_dom.
[Graphical view]
PfamPF01395. PBP_GOBP. 1 hit.
[Graphical view]
SUPFAMSSF47565. SSF47565. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi246671.
NextBio843429.

Entry information

Entry nameOB57D_DROME
AccessionPrimary (citable) accession number: Q8MMF9
Secondary accession number(s): Q5KS14 expand/collapse secondary AC list , Q5KS20, Q5KS26, Q5KS32, Q5KS34, Q8MVX5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: July 9, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase