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Protein

C-X-C motif chemokine

Gene

EGK_15773

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-X-C motif chemokineUniRule annotation
Gene namesi
ORF Names:EGK_15773Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21UniRule annotationAdd BLAST21
ChainiPRO_500999920522 – 94C-X-C motif chemokineUniRule annotationAdd BLAST73

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMMUG00000020904.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000027502.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 89SCYInterPro annotationAdd BLAST63

Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410JDG9. Eukaryota.
ENOG41117T8. LUCA.
HOGENOMiHOG000220915.
HOVERGENiHBG107789.
KOiK12672.
OMAiGGRCLCI.
OrthoDBiEOG091G0Z10.
TreeFamiTF333433.

Family and domain databases

CDDicd00273. Chemokine_CXC. 1 hit.
InterProiView protein in InterPro
IPR001089. Chemokine_CXC.
IPR018048. Chemokine_CXC_CS.
IPR001811. Chemokine_IL8-like_dom.
IPR033899. CXC_Chemokine_domain.
IPR027221. CXCL11.
IPR036048. Interleukin_8-like_sf.
PANTHERiPTHR10179. PTHR10179. 1 hit.
PTHR10179:SF28. PTHR10179:SF28. 1 hit.
PfamiView protein in Pfam
PF00048. IL8. 1 hit.
PRINTSiPR00437. SMALLCYTKCXC.
SMARTiView protein in SMART
SM00199. SCY. 1 hit.
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiView protein in PROSITE
PS00471. SMALL_CYTOKINES_CXC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8MIZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKGMAIAL AMILCTTVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI
60 70 80 90
IYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF
Length:94
Mass (Da):10,409
Last modified:October 1, 2002 - v1
Checksum:i87368E21908BF0CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY044447 mRNA. Translation: AAK95956.1.
CM001257 Genomic DNA. Translation: EHH25912.1.
RefSeqiNP_001028122.1. NM_001032950.1.
UniGeneiMmu.2724.

Genome annotation databases

GeneIDi574372.
KEGGimcc:574372.

Similar proteinsi

Entry informationi

Entry nameiQ8MIZ0_MACMU
AccessioniPrimary (citable) accession number: Q8MIZ0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: October 25, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)