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UniProtKB - Q8MIP5 (Q8MIP5_CANLF)

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Protein
Submitted name:

Melanin-concentrating hormone receptor subtype 2

Gene
N/A
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Melanin-concentrating hormone receptor subtype 2Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis ›

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei72 – 94HelicalSequence analysisAdd BLAST23
Transmembranei114 – 134HelicalSequence analysisAdd BLAST21
Transmembranei155 – 172HelicalSequence analysisAdd BLAST18
Transmembranei197 – 225HelicalSequence analysisAdd BLAST29
Transmembranei253 – 274HelicalSequence analysisAdd BLAST22
Transmembranei286 – 309HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8MIP5.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000005250.

Structurei

3D structure databases

ProteinModelPortaliQ8MIP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 306G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST256

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000000704.
HOVERGENiHBG098164.
KOiK05054.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008362. MCH2_receptor.
IPR008361. MCH_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR01784. MCH2RECEPTOR.
PR01783. MCHRECEPTOR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8MIP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSLHSSCWN TSAEPLNKSC NKEFAYHTLS ILDTXRLPSM IGIICSMGLV 
        60         70         80         90        100
GNILIVFTII RSRKKTIPDI YICNLAVADL VHIIGMPFLI HQWARGGEWV 
       110        120        130        140        150
FGGPLCTIIT SLDTCNQFAC SAIMTVMSID RYLALVQPFR LTSWRTRYKT 
       160        170        180        190        200
IRINLGLWAA SFILALPVWV YSKVIKFKDG VESCAFDLTS PDDVLRYTLY 
       210        220        230        240        250
LTITTFFFPL PLILVCYILI LCYTWEMYQQ NKDARCYNPS VPKERVMKLT 
       260        270        280        290        300
KMVLVLVAVF ILSAAPYHVI QLVNLKMQQP TLAFHVGYYL SICFSYASSS 
       310        320        330
INPFLYIMLS GNFRKRLPQV QRRVTEKSTI
Length:330
Mass (Da):37,759
Last modified:October 1, 2002 - v1
Checksum:i4AF3F85621A1CACB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY112659 mRNA. Translation: AAM51852.1.
RefSeqiNP_001003037.1. NM_001003037.1.
UniGeneiCfa.79.

Genome annotation databases

GeneIDi403562.
KEGGicfa:403562.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY112659 mRNA. Translation: AAM51852.1.
RefSeqiNP_001003037.1. NM_001003037.1.
UniGeneiCfa.79.

3D structure databases

ProteinModelPortaliQ8MIP5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000005250.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ8MIP5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi403562.
KEGGicfa:403562.

Organism-specific databases

CTDi84539.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000000704.
HOVERGENiHBG098164.
KOiK05054.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008362. MCH2_receptor.
IPR008361. MCH_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR01784. MCH2RECEPTOR.
PR01783. MCHRECEPTOR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8MIP5_CANLF
AccessioniPrimary (citable) accession number: Q8MIP5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: June 7, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.