Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8MIL8 (Q8MIL8_PIG) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismSus scrofa (Pig) EMBL AAM77472.1
Taxonomic identifier9823 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Protein attributes

Sequence length1209 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SAAS SAAS009030

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. RuleBase RU000307

Contains protein kinase domain. SAAS SAAS009030

Sequences

Sequence LengthMass (Da)Tools
Q8MIL8 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 268E3FB11E36F90F

FASTA1,209133,532
        10         20         30         40         50         60 
MRRSWAGGAA LLALLAAHFQ ASPALEEKKV CQGTSNKLTQ LGTFEDHFLS LQRMFNNCEV 

        70         80         90        100        110        120 
VLGNLEITYM QNSYNLSFLK TIQEVAGYVL IALNTVEKIP LENLQIIRGN VLYENTHALA 

       130        140        150        160        170        180 
VLSNYGANKT GLRELPMRNL QEILQGAVRF SNNPALCHAE SIQWRDIVNS DFLSNMSMDF 

       190        200        210        220        230        240 
QSQLGSCPKC DPGCLNGSCW GAGKENCQKL TKVICAQQCS GRCRGRSPSD CCHNQCAAGC 

       250        260        270        280        290        300 
TGPRESDCLV CRRFRDEATC KDTCPPLMLY NPTTYQMDVN PLGKYSFGAT CVKKCPRNYV 

       310        320        330        340        350        360 
VTDHGSCVRA CSSDSYEVEE DGVRKCKKCD GPCGKVCNGI GIGEFKDTLS INATNIKHFR 

       370        380        390        400        410        420 
NCTSISGDLH ILPVAFRGDS FTRTPPLDPK ELDILKTVKE ITGFLLIQAW PENRTGLHAF 

       430        440        450        460        470        480 
ENLEIIRGRT KQHGQFSLAV VGLDIASLGL RSLKEISDGD VIVSGNRNLC YANTISWKKL 

       490        500        510        520        530        540 
FGTASQKTKI INNRSEKECK AMGHICNPLC SSEGCWGPEP RDCMSCRNFS RGKECVEKCN 

       550        560        570        580        590        600 
VLEGEPREFV ENAECVQCHP ECLPQAKNVT CMGRGPDSCV RCAHYIDGPH CVKTCPAGIA 

       610        620        630        640        650        660 
GENSTLIWKF ADANHVCHLC HPNCTYGCVG PGLEGCAVDR PKIPSIATGI VGGLLLAVVL 

       670        680        690        700        710        720 
ALGVGLFLRR RHIVRKRTLR RLLQERELVE PLTPSGEAPN QALLRILKET EFKKVKVLGS 

       730        740        750        760        770        780 
GAFGTVYKGL WIPEGEKVKI PVAIKELREA TSPKANKEIL DEAYVMASVD NPHVCRLLGI 

       790        800        810        820        830        840 
CLTSTVQLIT QLMPFGCLLD YVREHKDNIG SQHLLNWCVQ IAKGMNYLED RRLVHRDLAA 

       850        860        870        880        890        900 
RNVLVKTPQH VKITDFGLAK LLGAEEKEYH AEGGKVPIKW LALESILHRV YTHQSDVWSY 

       910        920        930        940        950        960 
GVTVWELMTF GSKPYDGIPA SEISTVLEKG ERLPQPPICT IDVYMIMVKC WMIDADSRPK 

       970        980        990       1000       1010       1020 
FRELIIEFSK MARDPQRYLV IQGDERMHLP SPTDSNFYRA LMDEEDMEDV VDADEYLVPQ 

      1030       1040       1050       1060       1070       1080 
QGFFHSPATS RTPLLSSLSA TSSTPAVACV DRNGQSYPLK EDSFLQRYSS DPTGALTEDS 

      1090       1100       1110       1120       1130       1140 
LDDTFLPAPE YVNQSVPKRP AGSVQNPVYH NQPLSAAPGR DPHYQNSHSN AVGNPEYLNT 

      1150       1160       1170       1180       1190       1200 
PRPACINGGL DGPAFWAQTG SHQINLDNPD YQQAFFPKEA KSNGICKGPA AENAEYLRAA 


PASSDLTGA 

« Hide

References

[1]"Characterization of uterine epidermal growth factor receptor expression during the estrous cycle and early pregnancy in pigs."
Kim J.G., Vallet J.L., Nonneman D., Christenson R.K.
Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY117054 mRNA. Translation: AAM77472.1.
RefSeqNP_999172.1. NM_214007.1.
UniGeneSsc.54725.

3D structure databases

ProteinModelPortalQ8MIL8.
SMRQ8MIL8. Positions 25-636, 669-1003.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID397070.
KEGGssc:397070.

Organism-specific databases

CTD1956.

Phylogenomic databases

HOVERGENHBG000490.
KOK04361.

Family and domain databases

Gene3D3.80.20.20. 2 hits.
InterProIPR000494. EGF_rcpt_L.
IPR006211. Furin-like_Cys-rich_dom.
IPR006212. Furin_repeat.
IPR009030. Growth_fac_rcpt_N_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR016245. Tyr_kinase_EGF/ERB/XmrK_rcpt.
[Graphical view]
PfamPF00757. Furin-like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PF01030. Recep_L_domain. 2 hits.
[Graphical view]
PIRSFPIRSF000619. TyrPK_EGF-R. 1 hit.
PRINTSPR00109. TYRKINASE.
SMARTSM00261. FU. 5 hits.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8MIL8_PIG
AccessionPrimary (citable) accession number: Q8MIL8
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)