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Protein
Submitted name:

Ghrelin/growth hormone secretagogue receptor

Gene
N/A
Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Ghrelin/growth hormone secretagogue receptorImported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei42 – 6827HelicalSequence analysisAdd
BLAST
Transmembranei80 – 9819HelicalSequence analysisAdd
BLAST
Transmembranei118 – 13922HelicalSequence analysisAdd
BLAST
Transmembranei160 – 18425HelicalSequence analysisAdd
BLAST
Transmembranei212 – 23524HelicalSequence analysisAdd
BLAST
Transmembranei264 – 28623HelicalSequence analysisAdd
BLAST
Transmembranei306 – 32621HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL5015.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini60 – 323264G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG006538.
KOiK04284.

Family and domain databases

InterProiIPR003905. GHS-R.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01417. GHSRECEPTOR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8MHZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWNATRSEEL GPNLTLPDLD WDAAPDNDSL TDELPPLFPA PLLAGVTATC
60 70 80 90 100
VALFVVGIAG NLLTMLVVSR FRELRTTTNL YLSSMAFSDL LIFLCMPLDL
110 120 130 140 150
VRLWHYRPWN LGDLLCKLFQ FVSESCTYAS VLTITALSVE RYFAICFPLR
160 170 180 190 200
AKVVITKGRV KLVVLAIWAV AFCSAWPIFM LVGVEHENGT DPRDTNECRA
210 220 230 240 250
TEFAVRSGLL TIMVWVSSIF FFLPVFCLTV LYSLIGRKLW RRRRSEVVVG
260 270 280 290 300
ASLRDQNHKQ TVKMLAVVVF AFVLCWLPFH VGRYLFSKSF EPGSVEIAQI
310 320 330 340 350
SQYCNLVSFV LFYFSAAINP ILYNIMSKKY RVAVFKLLGF EPFSQRKLST
360
LKDESSRAWT ESSINT
Length:366
Mass (Da):41,487
Last modified:October 1, 2002 - v1
Checksum:i2F276651BC6C5D57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY093948 mRNA. Translation: AAM19733.1.
AY093949 mRNA. Translation: AAM19734.1.
AY093950 mRNA. Translation: AAM19735.1.
RefSeqiNP_001009760.1. NM_001009760.1.
UniGeneiOar.882.

Genome annotation databases

GeneIDi443238.
KEGGioas:443238.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY093948 mRNA. Translation: AAM19733.1.
AY093949 mRNA. Translation: AAM19734.1.
AY093950 mRNA. Translation: AAM19735.1.
RefSeqiNP_001009760.1. NM_001009760.1.
UniGeneiOar.882.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

ChEMBLiCHEMBL5015.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi443238.
KEGGioas:443238.

Organism-specific databases

CTDi2693.

Phylogenomic databases

HOVERGENiHBG006538.
KOiK04284.

Family and domain databases

InterProiIPR003905. GHS-R.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01417. GHSRECEPTOR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8MHZ5_SHEEP
AccessioniPrimary (citable) accession number: Q8MHZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: July 6, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.