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Protein

Putative L-type amino acid transporter 1-like protein MLAS

Gene

SLC7A5P1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:G66-32114-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L-type amino acid transporter 1-like protein MLAS
Alternative name(s):
hLAT1 3-transmembrane protein MLAS
Short name:
hLAT1 3TM MLAS
Gene namesi
Name:SLC7A5P1
Synonyms:MLAS
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:29458. SLC7A5P1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Transmembranei133 – 157HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi74750867.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003482511 – 180Putative L-type amino acid transporter 1-like protein MLASAdd BLAST180

Proteomic databases

MaxQBiQ8MH63.
PeptideAtlasiQ8MH63.
PRIDEiQ8MH63.

Expressioni

Tissue specificityi

Expressed in peripheral blood mononuclear cells and lymphoid and myeloid cell lines.1 Publication

Organism-specific databases

HPAiHPA052673.

Structurei

3D structure databases

ProteinModelPortaliQ8MH63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG061804.
InParanoidiQ8MH63.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8MH63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGAGPKRRA LAAPVAEEKE EAREKMLASK RADGAAPAGE GEGVTLQRNI
60 70 80 90 100
TLLNGVAIIV GAIIGSGIFV TPTGVLKEAG SPGLALVMWA ACGVFSIVGA
110 120 130 140 150
LCYAELGTTI SKSGGDYAYM LDVYGSLPAF LKLWIELLVI RPSSQYIVAL
160 170 180
VFATYLLKPL FPSCPVPEEA AKLMACHCVH
Length:180
Mass (Da):18,779
Last modified:October 1, 2002 - v1
Checksum:i60A302239800C3F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055226 mRNA. Translation: BAB97212.1.
UniGeneiHs.677169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB055226 mRNA. Translation: BAB97212.1.
UniGeneiHs.677169.

3D structure databases

ProteinModelPortaliQ8MH63.
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

DMDMi74750867.

Proteomic databases

MaxQBiQ8MH63.
PeptideAtlasiQ8MH63.
PRIDEiQ8MH63.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

CTDi81893.
GeneCardsiSLC7A5P1.
HGNCiHGNC:29458. SLC7A5P1.
HPAiHPA052673.
neXtProtiNX_Q8MH63.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG061804.
InParanoidiQ8MH63.

Enzyme and pathway databases

BioCyciZFISH:G66-32114-MONOMER.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAT1N_HUMAN
AccessioniPrimary (citable) accession number: Q8MH63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 1, 2002
Last modified: November 2, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.