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Q8MA03 (ODPB_CHAGL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismChaetosphaeridium globosum (Charophycean green alga) (Herposteiron globosum)
Taxonomic identifier96477 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaColeochaetophyceaeColeochaetalesChaetosphaeridiaceaeChaetosphaeridium

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 326326Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280101

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8MA03 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 9E99DFC6EBABDB3C

FASTA32635,969
        10         20         30         40         50         60 
MAEVLLFEAL RDALDEEMQR DPSVLVMGED VGHYGGSYKV TKGFHEKYGD LRLLDTPIAE 

        70         80         90        100        110        120 
NSFTGMAIGA AMTGLRPIVE GMNMGFLLLA FNQIANNAGM LHYTSGGNFK IPIVIRGPGG 

       130        140        150        160        170        180 
VGRQLGAEHS QRLESYFQSV PGLQMVACST PYNGKGLLKS AIRNDNPVIF FEHVLLYNLN 

       190        200        210        220        230        240 
ENLIEQEYLL CLEKAEVVRP GNDITILTYS RMRHHVLQAA KVLVNKGYDP EIIDILSLKP 

       250        260        270        280        290        300 
LDMGTISLSV RKTHKVLIVE ECMRTGGIGA SLRAAILEDL FDYLDAPIQC LSSQDVPTPY 

       310        320 
SGPLEELTVI QPNQIIQAVE EMCKIE 

« Hide

References

[1]"The chloroplast and mitochondrial genome sequences of the charophyte Chaetosphaeridium globosum: insights into the timing of the events that restructured organelle DNAs within the green algal lineage that led to land plants."
Turmel M., Otis C., Lemieux C.
Proc. Natl. Acad. Sci. U.S.A. 99:11275-11280(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M1311.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF494278 Genomic DNA. Translation: AAM96525.1.
RefSeqNP_683783.1. NC_004115.1.

3D structure databases

ProteinModelPortalQ8MA03.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID860807.

Phylogenomic databases

ProtClustDBCHL00144.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
InterProIPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_CHAGL
AccessionPrimary (citable) accession number: Q8MA03
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: October 1, 2002
Last modified: November 13, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program