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Q8LSN3 (FYPP_PEA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phytochrome-associated serine/threonine-protein phosphatase

EC=3.1.3.16
Alternative name(s):
PsFyPP
Gene names
Name:FYPP
OrganismPisum sativum (Garden pea)
Taxonomic identifier3888 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms. Plays a major role in the photoperiodic control of flowering time in long days by modulating phytochrome signals in flowering time control. Ref.1

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity. Ref.1

Subunit structure

Interacts with PHYA and PHYB, mostly when they are phosphorylated and in Pfr forms. Ref.1

Subcellular location

Cytoplasm Ref.1.

Tissue specificity

Mostly expressed in flowers and stems. Ref.1

Sequence similarities

Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandManganese
Metal-binding
Zinc
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303Phytochrome-associated serine/threonine-protein phosphatase
PRO_0000308994

Sites

Active site1111Proton donor By similarity
Metal binding501Manganese 1 By similarity
Metal binding521Manganese 1 By similarity
Metal binding781Manganese 1 By similarity
Metal binding781Manganese 2 By similarity
Metal binding1101Manganese 2 By similarity
Metal binding1601Manganese 2 By similarity
Metal binding2341Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8LSN3 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 32AF9A225DF9F9ED

FASTA30334,871
        10         20         30         40         50         60 
MDLDQWISKV KDGQHLLEDE LQLLCEYVKE ILIEESNVQP VNSPVTVCGD IHGQFHDLMK 

        70         80         90        100        110        120 
LFQTGGHVPE TNYIFMGDFV DRGYNSLEVF TILLLLKARY PANITLLRGN HESRQLTQVY 

       130        140        150        160        170        180 
GFYDECQRKY GNANAWRYCT DVFDYLTLSA IIDGTVLCVH GGLSPDIRTI DQIRVIERNC 

       190        200        210        220        230        240 
EIPHEGPFCD LMWSDPEDIE TWAVSPRGAG WLFGSRVTSE FNHINNLDLV CRAHQLVQEG 

       250        260        270        280        290        300 
LKYMFQDKGL VTVWSAPNYC YRCGNVASIL SFNENMEREV KFFTETEENN QMRGPRTGVP 


YFL 

« Hide

References

[1]"A phytochrome-associated protein phosphatase 2A modulates light signals in flowering time control in Arabidopsis."
Kim D.-H., Kang J.-G., Yang S.-S., Chung K.-S., Song P.-S., Park C.-M.
Plant Cell 14:3043-3056(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, COFACTOR, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH PHYA AND PHYB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF305635 mRNA. Translation: AAM21172.1.

3D structure databases

ProteinModelPortalQ8LSN3.
SMRQ8LSN3. Positions 2-277.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFYPP_PEA
AccessionPrimary (citable) accession number: Q8LSN3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families