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Q8LQ36 (ATX3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative ataxin-3 homolog

EC=3.4.19.12
Gene names
Ordered Locus Names:Os01g0851400, LOC_Os01g63250
ORF Names:P0529H11.31
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme By similarity.

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Subcellular location

Nucleus By similarity.

Sequence similarities

Contains 1 Josephin domain.

Contains 1 UIM (ubiquitin-interacting motif) repeat.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Putative ataxin-3 homolog
PRO_0000053837

Regions

Domain10 – 193184Josephin
Repeat244 – 26320UIM

Sites

Active site231Nucleophile By similarity
Active site1321Proton acceptor By similarity
Active site1471 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8LQ36 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 84020FBEA78E8715

FASTA33636,205
        10         20         30         40         50         60 
MEEAAAASNG GLLYHEVQEG KLCAVHCVNT TLQGPFFSEF DLSALAVDLD QRERQVMSEG 

        70         80         90        100        110        120 
AAGAATTAAG DFLAEGEGSH NVSLGGDFSI QVLQKALEVW DLQVIPLDSP DVGSCLFDPE 

       130        140        150        160        170        180 
LETAFICHLQ DHWFCIRKVN GEWYNFNSLY PAPEHLSKFY LSAFIDTLKG SGWSIFAVRG 

       190        200        210        220        230        240 
NFPKECPMAT EGSNGFGQWL TPDDARRITS SCNQVQTPTQ QAGVSLVADQ SEEMSEMDMI 

       250        260        270        280        290        300 
AAQQEEADLN AAIAASLMDT GGPFANYAAH EESRSQDAFA IESTSGEMSK DGNLEEQGAN 

       310        320        330 
KSETSEPNSD NIESASGSNP KQNTTSLEGK ESIKED 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004072 Genomic DNA. Translation: BAB92851.1.
RefSeqNP_001044821.2. NM_001051356.2.
UniGeneOs.7799.

3D structure databases

ProteinModelPortalQ8LQ36.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSC86.A01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS01T0851400-01; OS01T0851400-01; OS01G0851400.
GeneID4324808.
KEGGosa:4324808.

Organism-specific databases

GrameneQ8LQ36.

Phylogenomic databases

eggNOGNOG327234.
KOK11863.
OMAHCVNTTL.
ProtClustDBCLSN2685078.

Family and domain databases

InterProIPR006155. Josephin.
[Graphical view]
PfamPF02099. Josephin. 1 hit.
[Graphical view]
PRINTSPR01233. JOSEPHIN.
PROSITEPS50957. JOSEPHIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATX3_ORYSJ
AccessionPrimary (citable) accession number: Q8LQ36
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: October 1, 2002
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations