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Q8LQ36

- ATX3_ORYSJ

UniProt

Q8LQ36 - ATX3_ORYSJ

Protein

Putative ataxin-3 homolog

Gene

Os01g0851400

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme By similarity.By similarity

    Catalytic activityi

    Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei23 – 231NucleophilePROSITE-ProRule annotation
    Active sitei132 – 1321Proton acceptorPROSITE-ProRule annotation
    Active sitei147 – 1471PROSITE-ProRule annotation

    GO - Molecular functioni

    1. cysteine-type peptidase activity Source: UniProtKB-KW
    2. omega peptidase activity Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Keywords - Biological processi

    Transcription, Transcription regulation, Ubl conjugation pathway

    Protein family/group databases

    MEROPSiC86.A01.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative ataxin-3 homolog (EC:3.4.19.12)
    Gene namesi
    Ordered Locus Names:Os01g0851400, LOC_Os01g63250
    ORF Names:P0529H11.31
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 1

    Organism-specific databases

    GrameneiQ8LQ36.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 336336Putative ataxin-3 homologPRO_0000053837Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ8LQ36.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 193184JosephinPROSITE-ProRule annotationAdd
    BLAST
    Repeati244 – 26320UIMAdd
    BLAST

    Sequence similaritiesi

    Contains 1 Josephin domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG327234.
    KOiK11863.
    OMAiLMDTGGP.

    Family and domain databases

    InterProiIPR006155. Josephin.
    [Graphical view]
    PfamiPF02099. Josephin. 1 hit.
    [Graphical view]
    PRINTSiPR01233. JOSEPHIN.
    PROSITEiPS50957. JOSEPHIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8LQ36-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEAAAASNG GLLYHEVQEG KLCAVHCVNT TLQGPFFSEF DLSALAVDLD    50
    QRERQVMSEG AAGAATTAAG DFLAEGEGSH NVSLGGDFSI QVLQKALEVW 100
    DLQVIPLDSP DVGSCLFDPE LETAFICHLQ DHWFCIRKVN GEWYNFNSLY 150
    PAPEHLSKFY LSAFIDTLKG SGWSIFAVRG NFPKECPMAT EGSNGFGQWL 200
    TPDDARRITS SCNQVQTPTQ QAGVSLVADQ SEEMSEMDMI AAQQEEADLN 250
    AAIAASLMDT GGPFANYAAH EESRSQDAFA IESTSGEMSK DGNLEEQGAN 300
    KSETSEPNSD NIESASGSNP KQNTTSLEGK ESIKED 336
    Length:336
    Mass (Da):36,205
    Last modified:October 1, 2002 - v1
    Checksum:i84020FBEA78E8715
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004072 Genomic DNA. Translation: BAB92851.1.
    RefSeqiNP_001044821.2. NM_001051356.2.
    UniGeneiOs.7799.

    Genome annotation databases

    EnsemblPlantsiOS01T0851400-01; OS01T0851400-01; OS01G0851400.
    GeneIDi4324808.
    KEGGiosa:4324808.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004072 Genomic DNA. Translation: BAB92851.1 .
    RefSeqi NP_001044821.2. NM_001051356.2.
    UniGenei Os.7799.

    3D structure databases

    ProteinModelPortali Q8LQ36.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi C86.A01.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS01T0851400-01 ; OS01T0851400-01 ; OS01G0851400 .
    GeneIDi 4324808.
    KEGGi osa:4324808.

    Organism-specific databases

    Gramenei Q8LQ36.

    Phylogenomic databases

    eggNOGi NOG327234.
    KOi K11863.
    OMAi LMDTGGP.

    Family and domain databases

    InterProi IPR006155. Josephin.
    [Graphical view ]
    Pfami PF02099. Josephin. 1 hit.
    [Graphical view ]
    PRINTSi PR01233. JOSEPHIN.
    PROSITEi PS50957. JOSEPHIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence and structure of rice chromosome 1."
      Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.
      , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
      Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiATX3_ORYSJ
    AccessioniPrimary (citable) accession number: Q8LQ36
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 24, 2006
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3