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Protein

Putative ataxin-3 homolog

Gene

Os01g0851400

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme (By similarity).By similarity

Catalytic activityi

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei23NucleophilePROSITE-ProRule annotation1
Active sitei132Proton acceptorPROSITE-ProRule annotation1
Active sitei147PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Keywords - Biological processi

Transcription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

ReactomeiR-OSA-5689877. Josephin domain DUBs.

Protein family/group databases

MEROPSiC86.A01.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ataxin-3 homolog (EC:3.4.19.12)
Gene namesi
Ordered Locus Names:Os01g0851400, LOC_Os01g63250
ORF Names:P0529H11.31
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000538371 – 336Putative ataxin-3 homologAdd BLAST336

Proteomic databases

PaxDbiQ8LQ36.

Expressioni

Gene expression databases

GenevisibleiQ8LQ36. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g63250.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LQ36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 193JosephinPROSITE-ProRule annotationAdd BLAST184
Domaini244 – 263UIMCuratedAdd BLAST20

Sequence similaritiesi

Contains 1 Josephin domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2935. Eukaryota.
ENOG4111G4B. LUCA.
InParanoidiQ8LQ36.
KOiK11863.
OMAiRQVMLQG.
OrthoDBiEOG09360KCU.

Family and domain databases

InterProiIPR033865. Ataxin-3.
IPR006155. Josephin.
[Graphical view]
PANTHERiPTHR14159. PTHR14159. 1 hit.
PfamiPF02099. Josephin. 1 hit.
[Graphical view]
SMARTiSM01246. Josephin. 1 hit.
[Graphical view]
PROSITEiPS50957. JOSEPHIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8LQ36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEAAAASNG GLLYHEVQEG KLCAVHCVNT TLQGPFFSEF DLSALAVDLD
60 70 80 90 100
QRERQVMSEG AAGAATTAAG DFLAEGEGSH NVSLGGDFSI QVLQKALEVW
110 120 130 140 150
DLQVIPLDSP DVGSCLFDPE LETAFICHLQ DHWFCIRKVN GEWYNFNSLY
160 170 180 190 200
PAPEHLSKFY LSAFIDTLKG SGWSIFAVRG NFPKECPMAT EGSNGFGQWL
210 220 230 240 250
TPDDARRITS SCNQVQTPTQ QAGVSLVADQ SEEMSEMDMI AAQQEEADLN
260 270 280 290 300
AAIAASLMDT GGPFANYAAH EESRSQDAFA IESTSGEMSK DGNLEEQGAN
310 320 330
KSETSEPNSD NIESASGSNP KQNTTSLEGK ESIKED
Length:336
Mass (Da):36,205
Last modified:October 1, 2002 - v1
Checksum:i84020FBEA78E8715
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004072 Genomic DNA. Translation: BAB92851.1.
AP008207 Genomic DNA. Translation: BAF06735.2.
AP014957 Genomic DNA. Translation: BAS75251.1.
RefSeqiXP_015614266.1. XM_015758780.1.
UniGeneiOs.7799.

Genome annotation databases

EnsemblPlantsiOS01T0851400-01; OS01T0851400-01; OS01G0851400.
GeneIDi4324808.
GrameneiOS01T0851400-01; OS01T0851400-01; OS01G0851400.
KEGGiosa:4324808.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004072 Genomic DNA. Translation: BAB92851.1.
AP008207 Genomic DNA. Translation: BAF06735.2.
AP014957 Genomic DNA. Translation: BAS75251.1.
RefSeqiXP_015614266.1. XM_015758780.1.
UniGeneiOs.7799.

3D structure databases

ProteinModelPortaliQ8LQ36.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g63250.1.

Protein family/group databases

MEROPSiC86.A01.

Proteomic databases

PaxDbiQ8LQ36.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0851400-01; OS01T0851400-01; OS01G0851400.
GeneIDi4324808.
GrameneiOS01T0851400-01; OS01T0851400-01; OS01G0851400.
KEGGiosa:4324808.

Phylogenomic databases

eggNOGiKOG2935. Eukaryota.
ENOG4111G4B. LUCA.
InParanoidiQ8LQ36.
KOiK11863.
OMAiRQVMLQG.
OrthoDBiEOG09360KCU.

Enzyme and pathway databases

ReactomeiR-OSA-5689877. Josephin domain DUBs.

Gene expression databases

GenevisibleiQ8LQ36. OS.

Family and domain databases

InterProiIPR033865. Ataxin-3.
IPR006155. Josephin.
[Graphical view]
PANTHERiPTHR14159. PTHR14159. 1 hit.
PfamiPF02099. Josephin. 1 hit.
[Graphical view]
SMARTiSM01246. Josephin. 1 hit.
[Graphical view]
PROSITEiPS50957. JOSEPHIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATX3_ORYSJ
AccessioniPrimary (citable) accession number: Q8LQ36
Secondary accession number(s): Q0JHP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: October 1, 2002
Last modified: November 30, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.