ID   CMT3_MAIZE              Reviewed;         915 AA.
AC   Q8LPU5;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 34.
DE   RecName: Full=DNA (cytosine-5)-methyltransferase 3;
DE            EC=2.1.1.37;
DE   AltName: Full=Chromomethylase 3;
DE   AltName: Full=DNA methyltransferase 105;
GN   Name=DMT105;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae;
OC   PACCAD clade; Panicoideae; Andropogoneae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chandler V.L., Kaeppler S.M., Kaeppler H.F., Cone K.C.;
RT   "Sequences from the plant chromatin consortium.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Bergstrom D., Springer N.M., Schmitt L.T., Guthrie E., Sidorenko L.,
RA   Selinger D., Kaeppler S.M., Cone K.C.;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the CpXpG methylation and in gene
CC       silencing (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + DNA = S-adenosyl-L-
CC       homocysteine + DNA containing 5-methylcytosine.
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- SIMILARITY: Belongs to the C5-methyltransferase family.
CC   -!- SIMILARITY: Contains 1 BAH domain.
CC   -!- SIMILARITY: Contains 1 chromo domain.
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DR   EMBL; AY093416; AAM28227.1; -; mRNA.
DR   UniGene; Zm.599; -.
DR   HSSP; P83917; 1AP0.
DR   REBASE; 5016; M.ZmaV.
DR   Gramene; Q8LPU5; -.
DR   BRENDA; 2.1.1.37; 289.
DR   GO; GO:0000785; C:chromatin; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:EC.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR001025; BAH.
DR   InterPro; IPR001525; C5_DNA_meth.
DR   InterPro; IPR018117; C5_DNA_meth_AS.
DR   InterPro; IPR000953; Chromodomain.
DR   PANTHER; PTHR10629; C5_DNA_meth; 1.
DR   Pfam; PF01426; BAH; 1.
DR   Pfam; PF00385; Chromo; 1.
DR   Pfam; PF00145; DNA_methylase; 2.
DR   PRINTS; PR00105; C5METTRFRASE.
DR   SMART; SM00439; BAH; 1.
DR   SMART; SM00298; CHROMO; 1.
DR   PROSITE; PS51038; BAH; 1.
DR   PROSITE; PS00094; C5_MTASE_1; 1.
DR   PROSITE; PS00598; CHROMO_1; FALSE_NEG.
DR   PROSITE; PS50013; CHROMO_2; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator; DNA-binding; Methyltransferase; Nucleus;
KW   S-adenosyl-L-methionine; Transcription; Transcription regulation;
KW   Transferase.
FT   CHAIN         1    915       DNA (cytosine-5)-methyltransferase 3.
FT                                /FTId=PRO_0000246696.
FT   DOMAIN      188    313       BAH.
FT   DOMAIN      445    508       Chromo.
SQ   SEQUENCE   915 AA;  101611 MW;  D1F4031F729C6A56 CRC64;
     MAPSSPSSAR PTRASGRKRS AMAEEIHQNQ EEEEEVVAAS TAKRRRKAAS SGKKPKPTPK
     QAKPAVAGMK KKGETEKTEP VVDDVCAEEP DEEELAMGEE EAEAEEQAMQ EVVAAVAAGS
     PGKKRVGRRS AAASGDHVPE FIGSPVAAAE AHSNWPKRYE RSTAANKPEE DDELKARCHY
     RSAKVDNIVY CLGDDVYVKA GENEADYIGR ITEFFEGTDR CHYFTCRWFF RAEDTVINSL
     VSINVDGHKH DPRRVFLSEE KNDNVLDCII SKVKIVHVDP NMDPKAKAQL IEHCDLYYDM
     SYSVAYSTFA NISSENGQSG SETASGISSD DAGLETSSNM PERTATLLDL YSGCGGMSTG
     LCLGAALSGL KLETRWAVDL NSFACQSLKY NHPQTEVRNE KADEFLALLK EWAVLCEKYV
     HQDVDSNLAG SEDQEDADTL DKDEFVVQKL IGIRYDGTGR KKGVYFKVQW EGYGPEEDTW
     EPIDNLSDCP LKIREFVQEG RKRKILPLPG DVDVICGGPP CQGISGFNRF RNRDEPLKDE
     KNKQMVTFMD IVAYLKPKYV LMENVVDILK FADGYLGKYA LSCLVAMKYQ ARLGMMVAGC
     YGLPQFRMRV FLWGALSSMV LPKYPLPTYD VVVRGGAPNA FSQCMVAYDE TQRPSLKKAL
     LLGDAFSDLP KVENHQPNDV MEYGGSPKTE FQRYIRLGRK DMLDWSFGEE AGPDEGKLLD
     HQPLRLNNDD YERVKQIPVK KGANFRDLKG VKVGANNVVE WDPEVERVYL SSGKPLVPDY
     AMSFIKGKSL KPFGRLWWDE TVPTVVTRAE PHNQVILHPT QARVLTIREN ARLQGFPDYY
     RLFGPIKEKY IQVGNAVAVP VARALGYCLG QAYLGESDGS QPLYQLPASF TSVGRTAVQA
     NAVSVGTPAG EVVEQ
//