SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8LPU5

- CMT3_MAIZE

UniProt

Q8LPU5 - CMT3_MAIZE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

DNA (cytosine-5)-methyltransferase 3

Gene
DMT105
Organism
Zea mays (Maize)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May be involved in the CpXpG methylation and in gene silencing By similarity.

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei521 – 5211 By similarity

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
  3. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. chromatin silencing Source: EnsemblPlants/Gramene
  2. DNA mediated transformation Source: EnsemblPlants/Gramene
  3. DNA methylation on cytosine within a CNG sequence Source: EnsemblPlants/Gramene
  4. histone H3-K9 methylation Source: EnsemblPlants/Gramene
  5. transcription, DNA-templated Source: UniProtKB-KW
  6. zygote asymmetric cytokinesis in embryo sac Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Methyltransferase, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, S-adenosyl-L-methionine

Protein family/group databases

REBASEi5016. M.ZmaV.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA (cytosine-5)-methyltransferase 3 (EC:2.1.1.37)
Alternative name(s):
Chromomethylase 3
DNA methyltransferase 105
Gene namesi
Name:DMT105
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Organism-specific databases

GrameneiQ8LPU5.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 915915DNA (cytosine-5)-methyltransferase 3PRO_0000246696Add
BLAST

Proteomic databases

PRIDEiQ8LPU5.

Structurei

3D structure databases

ProteinModelPortaliQ8LPU5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini188 – 313126BAHAdd
BLAST
Domaini345 – 876532SAM-dependent MTase C5-typeAdd
BLAST
Domaini445 – 50864ChromoAdd
BLAST

Sequence similaritiesi

Contains 1 BAH domain.
Contains 1 chromo domain.

Phylogenomic databases

OMAiFGMASQG.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR001025. BAH_dom.
IPR018117. C5_DNA_meth_AS.
IPR001525. C5_MeTfrase.
IPR025821. C5_MeTfrase_pln.
IPR023780. Chromo_domain.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PANTHERiPTHR10629. PTHR10629. 1 hit.
PfamiPF01426. BAH. 1 hit.
PF00385. Chromo. 1 hit.
PF00145. DNA_methylase. 1 hit.
[Graphical view]
PRINTSiPR00105. C5METTRFRASE.
SMARTiSM00439. BAH. 1 hit.
SM00298. CHROMO. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 4 hits.
SSF54160. SSF54160. 1 hit.
PROSITEiPS51038. BAH. 1 hit.
PS00094. C5_MTASE_1. 1 hit.
PS50013. CHROMO_2. 1 hit.
PS51679. SAM_MT_C5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8LPU5-1 [UniParc]FASTAAdd to Basket

« Hide

MAPSSPSSAR PTRASGRKRS AMAEEIHQNQ EEEEEVVAAS TAKRRRKAAS    50
SGKKPKPTPK QAKPAVAGMK KKGETEKTEP VVDDVCAEEP DEEELAMGEE 100
EAEAEEQAMQ EVVAAVAAGS PGKKRVGRRS AAASGDHVPE FIGSPVAAAE 150
AHSNWPKRYE RSTAANKPEE DDELKARCHY RSAKVDNIVY CLGDDVYVKA 200
GENEADYIGR ITEFFEGTDR CHYFTCRWFF RAEDTVINSL VSINVDGHKH 250
DPRRVFLSEE KNDNVLDCII SKVKIVHVDP NMDPKAKAQL IEHCDLYYDM 300
SYSVAYSTFA NISSENGQSG SETASGISSD DAGLETSSNM PERTATLLDL 350
YSGCGGMSTG LCLGAALSGL KLETRWAVDL NSFACQSLKY NHPQTEVRNE 400
KADEFLALLK EWAVLCEKYV HQDVDSNLAG SEDQEDADTL DKDEFVVQKL 450
IGIRYDGTGR KKGVYFKVQW EGYGPEEDTW EPIDNLSDCP LKIREFVQEG 500
RKRKILPLPG DVDVICGGPP CQGISGFNRF RNRDEPLKDE KNKQMVTFMD 550
IVAYLKPKYV LMENVVDILK FADGYLGKYA LSCLVAMKYQ ARLGMMVAGC 600
YGLPQFRMRV FLWGALSSMV LPKYPLPTYD VVVRGGAPNA FSQCMVAYDE 650
TQRPSLKKAL LLGDAFSDLP KVENHQPNDV MEYGGSPKTE FQRYIRLGRK 700
DMLDWSFGEE AGPDEGKLLD HQPLRLNNDD YERVKQIPVK KGANFRDLKG 750
VKVGANNVVE WDPEVERVYL SSGKPLVPDY AMSFIKGKSL KPFGRLWWDE 800
TVPTVVTRAE PHNQVILHPT QARVLTIREN ARLQGFPDYY RLFGPIKEKY 850
IQVGNAVAVP VARALGYCLG QAYLGESDGS QPLYQLPASF TSVGRTAVQA 900
NAVSVGTPAG EVVEQ 915
Length:915
Mass (Da):101,611
Last modified:October 1, 2002 - v1
Checksum:iD1F4031F729C6A56
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY093416 mRNA. Translation: AAM28227.1.
UniGeneiZm.599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY093416 mRNA. Translation: AAM28227.1 .
UniGenei Zm.599.

3D structure databases

ProteinModelPortali Q8LPU5.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

REBASEi 5016. M.ZmaV.

Proteomic databases

PRIDEi Q8LPU5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q8LPU5.

Phylogenomic databases

OMAi FGMASQG.

Family and domain databases

Gene3Di 3.40.50.150. 2 hits.
InterProi IPR001025. BAH_dom.
IPR018117. C5_DNA_meth_AS.
IPR001525. C5_MeTfrase.
IPR025821. C5_MeTfrase_pln.
IPR023780. Chromo_domain.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
PANTHERi PTHR10629. PTHR10629. 1 hit.
Pfami PF01426. BAH. 1 hit.
PF00385. Chromo. 1 hit.
PF00145. DNA_methylase. 1 hit.
[Graphical view ]
PRINTSi PR00105. C5METTRFRASE.
SMARTi SM00439. BAH. 1 hit.
SM00298. CHROMO. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 4 hits.
SSF54160. SSF54160. 1 hit.
PROSITEi PS51038. BAH. 1 hit.
PS00094. C5_MTASE_1. 1 hit.
PS50013. CHROMO_2. 1 hit.
PS51679. SAM_MT_C5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequences from the plant chromatin consortium."
    Chandler V.L., Kaeppler S.M., Kaeppler H.F., Cone K.C.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Bergstrom D., Springer N.M., Schmitt L.T., Guthrie E., Sidorenko L., Selinger D., Kaeppler S.M., Cone K.C.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiCMT3_MAIZE
AccessioniPrimary (citable) accession number: Q8LPU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi