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Q8LI34

- MYST1_ORYSJ

UniProt

Q8LI34 - MYST1_ORYSJ

Protein

Putative MYST-like histone acetyltransferase 1

Gene

Os07g0626600

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Histone acetyltransferase which may be involved in transcriptional activation.By similarity

    Catalytic activityi

    Acetyl-CoA + [histone] = CoA + acetyl-[histone].

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei274 – 2741By similarity
    Active sitei316 – 3161NucleophileBy similarity
    Binding sitei319 – 3191Acetyl-CoABy similarity
    Binding sitei354 – 3541Acetyl-CoABy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri208 – 23023C2HC-typeAdd
    BLAST

    GO - Molecular functioni

    1. histone acetyltransferase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. DNA repair Source: EnsemblPlants/Gramene
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. response to UV-B Source: EnsemblPlants/Gramene
    4. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator, Acyltransferase, Chromatin regulator, Transferase

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative MYST-like histone acetyltransferase 1 (EC:2.3.1.48)
    Gene namesi
    Ordered Locus Names:Os07g0626600, LOC_Os07g43360
    ORF Names:OJ1339_F05.128
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 7

    Organism-specific databases

    GrameneiQ8LI34.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 450450Putative MYST-like histone acetyltransferase 1PRO_0000238466Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei274 – 2741N6-acetyllysine; by autocatalysisBy similarity

    Post-translational modificationi

    Autoacetylation at Lys-274 is required for proper function.By similarity

    Keywords - PTMi

    Acetylation

    Structurei

    3D structure databases

    ProteinModelPortaliQ8LI34.
    SMRiQ8LI34. Positions 177-445.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini77 – 13761ChromoAdd
    BLAST
    Domaini174 – 445272MYST-type HATAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni324 – 3307Acetyl-CoA bindingBy similarity

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi6 – 3833Ala-richAdd
    BLAST
    Compositional biasi28 – 347Poly-Gly

    Sequence similaritiesi

    Belongs to the MYST (SAS/MOZ) family.Curated
    Contains 1 C2HC-type zinc finger.Curated
    Contains 1 chromo domain.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri208 – 23023C2HC-typeAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiCOG5027.
    HOGENOMiHOG000182457.
    KOiK11308.
    OMAiPPEYNDS.

    Family and domain databases

    Gene3Di3.40.630.30. 1 hit.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR000953. Chromo_domain/shadow.
    IPR016197. Chromodomain-like.
    IPR002717. MOZ_SAS.
    IPR025995. Tudor-knot.
    IPR015880. Znf_C2H2-like.
    [Graphical view]
    PfamiPF01853. MOZ_SAS. 1 hit.
    PF11717. Tudor-knot. 1 hit.
    [Graphical view]
    SMARTiSM00298. CHROMO. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view]
    SUPFAMiSSF54160. SSF54160. 1 hit.
    SSF55729. SSF55729. 1 hit.
    PROSITEiPS51726. MYST_HAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8LI34-1 [UniParc]FASTAAdd to Basket

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    MGSMEASTAP ENGTAAAAAA AASTACNGAG GGGGAAAASN GGGVERRLRS    50
    SAASASWASH LPLEVGTRVM CRWRDQKLHP VKVIERRKSS TSSSPADYEY 100
    YVHYTEFNRR LDEWVKLEQL DLETVETDVD EKVEDKATSL KMTRHQKRKI 150
    DETHVEQGHE ELDAASLREH EEFTKVKNIA KIELGRYEID TWYFSPFPPE 200
    YNDSPKLFFC EFCLNFMKRK EQLQRHMKKC DLKHPPGDEI YRSGTLSMFE 250
    VDGKKNKVYG QNLCYLAKLF LDHKTLYYDV DLFLFYVLCE CDDRGCHMVG 300
    YFSKEKHSEE SYNLACILTL PPYQRKGYGK FLIAFSYELS KKEGKVGTPE 350
    RPLSDLGLLS YRGYWTRVLL EILKKHKSNI SIKELSDMTA IKADDILSTL 400
    QSLDLIQYRK GQHVICADPK VLDRHLKAAG RGGLEVDVSK LIWTPYKEQG 450
    Length:450
    Mass (Da):51,104
    Last modified:October 1, 2002 - v1
    Checksum:i18BABF1963015A34
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004009 Genomic DNA. Translation: BAC07072.1.
    RefSeqiNP_001060338.1. NM_001066873.1.
    UniGeneiOs.9844.

    Genome annotation databases

    EnsemblPlantsiOS07T0626600-01; OS07T0626600-01; OS07G0626600.
    GeneIDi4343971.
    KEGGiosa:4343971.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004009 Genomic DNA. Translation: BAC07072.1 .
    RefSeqi NP_001060338.1. NM_001066873.1.
    UniGenei Os.9844.

    3D structure databases

    ProteinModelPortali Q8LI34.
    SMRi Q8LI34. Positions 177-445.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS07T0626600-01 ; OS07T0626600-01 ; OS07G0626600 .
    GeneIDi 4343971.
    KEGGi osa:4343971.

    Organism-specific databases

    Gramenei Q8LI34.

    Phylogenomic databases

    eggNOGi COG5027.
    HOGENOMi HOG000182457.
    KOi K11308.
    OMAi PPEYNDS.

    Family and domain databases

    Gene3Di 3.40.630.30. 1 hit.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR000953. Chromo_domain/shadow.
    IPR016197. Chromodomain-like.
    IPR002717. MOZ_SAS.
    IPR025995. Tudor-knot.
    IPR015880. Znf_C2H2-like.
    [Graphical view ]
    Pfami PF01853. MOZ_SAS. 1 hit.
    PF11717. Tudor-knot. 1 hit.
    [Graphical view ]
    SMARTi SM00298. CHROMO. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54160. SSF54160. 1 hit.
    SSF55729. SSF55729. 1 hit.
    PROSITEi PS51726. MYST_HAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiMYST1_ORYSJ
    AccessioniPrimary (citable) accession number: Q8LI34
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3