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Q8LI34

- MYST1_ORYSJ

UniProt

Q8LI34 - MYST1_ORYSJ

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Protein
Putative MYST-like histone acetyltransferase 1
Gene
Os07g0626600, LOC_Os07g43360, OJ1339_F05.128
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Histone acetyltransferase which may be involved in transcriptional activation By similarity.

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei274 – 2741 By similarity
Active sitei316 – 3161Nucleophile By similarity
Binding sitei319 – 3191Acetyl-CoA By similarity
Binding sitei354 – 3541Acetyl-CoA By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri208 – 23023C2HC-type
Add
BLAST

GO - Molecular functioni

  1. histone acetyltransferase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. DNA repair Source: EnsemblPlants/Gramene
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. response to UV-B Source: EnsemblPlants/Gramene
  4. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Acyltransferase, Chromatin regulator, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative MYST-like histone acetyltransferase 1 (EC:2.3.1.48)
Gene namesi
Ordered Locus Names:Os07g0626600, LOC_Os07g43360
ORF Names:OJ1339_F05.128
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 7

Organism-specific databases

GrameneiQ8LI34.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Putative MYST-like histone acetyltransferase 1
PRO_0000238466Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei274 – 2741N6-acetyllysine; by autocatalysis By similarity

Post-translational modificationi

Autoacetylation at Lys-274 is required for proper function By similarity.

Keywords - PTMi

Acetylation

Structurei

3D structure databases

ProteinModelPortaliQ8LI34.
SMRiQ8LI34. Positions 177-445.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini77 – 13761Chromo
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni324 – 3307Acetyl-CoA binding By similarity

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi6 – 3833Ala-rich
Add
BLAST
Compositional biasi28 – 347Poly-Gly

Sequence similaritiesi

Belongs to the MYST (SAS/MOZ) family.
Contains 1 chromo domain.

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG5027.
HOGENOMiHOG000182457.
KOiK11308.
OMAiPPEYNDS.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8LI34-1 [UniParc]FASTAAdd to Basket

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MGSMEASTAP ENGTAAAAAA AASTACNGAG GGGGAAAASN GGGVERRLRS    50
SAASASWASH LPLEVGTRVM CRWRDQKLHP VKVIERRKSS TSSSPADYEY 100
YVHYTEFNRR LDEWVKLEQL DLETVETDVD EKVEDKATSL KMTRHQKRKI 150
DETHVEQGHE ELDAASLREH EEFTKVKNIA KIELGRYEID TWYFSPFPPE 200
YNDSPKLFFC EFCLNFMKRK EQLQRHMKKC DLKHPPGDEI YRSGTLSMFE 250
VDGKKNKVYG QNLCYLAKLF LDHKTLYYDV DLFLFYVLCE CDDRGCHMVG 300
YFSKEKHSEE SYNLACILTL PPYQRKGYGK FLIAFSYELS KKEGKVGTPE 350
RPLSDLGLLS YRGYWTRVLL EILKKHKSNI SIKELSDMTA IKADDILSTL 400
QSLDLIQYRK GQHVICADPK VLDRHLKAAG RGGLEVDVSK LIWTPYKEQG 450
Length:450
Mass (Da):51,104
Last modified:October 1, 2002 - v1
Checksum:i18BABF1963015A34
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004009 Genomic DNA. Translation: BAC07072.1.
RefSeqiNP_001060338.1. NM_001066873.1.
UniGeneiOs.9844.

Genome annotation databases

EnsemblPlantsiOS07T0626600-01; OS07T0626600-01; OS07G0626600.
GeneIDi4343971.
KEGGiosa:4343971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004009 Genomic DNA. Translation: BAC07072.1 .
RefSeqi NP_001060338.1. NM_001066873.1.
UniGenei Os.9844.

3D structure databases

ProteinModelPortali Q8LI34.
SMRi Q8LI34. Positions 177-445.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS07T0626600-01 ; OS07T0626600-01 ; OS07G0626600 .
GeneIDi 4343971.
KEGGi osa:4343971.

Organism-specific databases

Gramenei Q8LI34.

Phylogenomic databases

eggNOGi COG5027.
HOGENOMi HOG000182457.
KOi K11308.
OMAi PPEYNDS.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view ]
SMARTi SM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
SUPFAMi SSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiMYST1_ORYSJ
AccessioniPrimary (citable) accession number: Q8LI34
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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