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Protein

Putative MYST-like histone acetyltransferase 1

Gene

Os07g0626600

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Histone acetyltransferase which may be involved in transcriptional activation.By similarity

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei350 – 3501Proton donor/acceptorBy similarity
Binding sitei354 – 3541Acetyl-CoABy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri208 – 23023C2HC-typeAdd
BLAST

GO - Molecular functioni

  1. histone acetyltransferase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Acyltransferase, Chromatin regulator, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative MYST-like histone acetyltransferase 1 (EC:2.3.1.48By similarity)
Gene namesi
Ordered Locus Names:Os07g0626600, LOC_Os07g43360
ORF Names:OJ1339_F05.128
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763 Componenti: Chromosome 7

Organism-specific databases

GrameneiQ8LI34.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Putative MYST-like histone acetyltransferase 1PRO_0000238466Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei274 – 2741N6-acetyllysine; by autocatalysisBy similarity

Post-translational modificationi

Autoacetylation at Lys-274 is required for proper function.By similarity

Keywords - PTMi

Acetylation

Expressioni

Gene expression databases

ExpressionAtlasiQ8LI34. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ8LI34.
SMRiQ8LI34. Positions 177-445.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini77 – 13761ChromoAdd
BLAST
Domaini174 – 445272MYST-type HATAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni317 – 3193Acetyl-CoA bindingBy similarity
Regioni324 – 3307Acetyl-CoA bindingBy similarity

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi6 – 3833Ala-richAdd
BLAST
Compositional biasi28 – 347Poly-Gly

Sequence similaritiesi

Belongs to the MYST (SAS/MOZ) family.Curated
Contains 1 C2HC-type zinc finger.Curated
Contains 1 chromo domain.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri208 – 23023C2HC-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG5027.
HOGENOMiHOG000182457.
InParanoidiQ8LI34.
KOiK11308.
OMAiEYNDSPK.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo/shadow_dom.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51726. MYST_HAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8LI34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSMEASTAP ENGTAAAAAA AASTACNGAG GGGGAAAASN GGGVERRLRS
60 70 80 90 100
SAASASWASH LPLEVGTRVM CRWRDQKLHP VKVIERRKSS TSSSPADYEY
110 120 130 140 150
YVHYTEFNRR LDEWVKLEQL DLETVETDVD EKVEDKATSL KMTRHQKRKI
160 170 180 190 200
DETHVEQGHE ELDAASLREH EEFTKVKNIA KIELGRYEID TWYFSPFPPE
210 220 230 240 250
YNDSPKLFFC EFCLNFMKRK EQLQRHMKKC DLKHPPGDEI YRSGTLSMFE
260 270 280 290 300
VDGKKNKVYG QNLCYLAKLF LDHKTLYYDV DLFLFYVLCE CDDRGCHMVG
310 320 330 340 350
YFSKEKHSEE SYNLACILTL PPYQRKGYGK FLIAFSYELS KKEGKVGTPE
360 370 380 390 400
RPLSDLGLLS YRGYWTRVLL EILKKHKSNI SIKELSDMTA IKADDILSTL
410 420 430 440 450
QSLDLIQYRK GQHVICADPK VLDRHLKAAG RGGLEVDVSK LIWTPYKEQG
Length:450
Mass (Da):51,104
Last modified:October 1, 2002 - v1
Checksum:i18BABF1963015A34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004009 Genomic DNA. Translation: BAC07072.1.
RefSeqiNP_001060338.1. NM_001066873.1.
UniGeneiOs.9844.

Genome annotation databases

EnsemblPlantsiOS07T0626600-01; OS07T0626600-01; OS07G0626600.
GeneIDi4343971.
KEGGiosa:4343971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004009 Genomic DNA. Translation: BAC07072.1.
RefSeqiNP_001060338.1. NM_001066873.1.
UniGeneiOs.9844.

3D structure databases

ProteinModelPortaliQ8LI34.
SMRiQ8LI34. Positions 177-445.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS07T0626600-01; OS07T0626600-01; OS07G0626600.
GeneIDi4343971.
KEGGiosa:4343971.

Organism-specific databases

GrameneiQ8LI34.

Phylogenomic databases

eggNOGiCOG5027.
HOGENOMiHOG000182457.
InParanoidiQ8LI34.
KOiK11308.
OMAiEYNDSPK.

Gene expression databases

ExpressionAtlasiQ8LI34. baseline.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo/shadow_dom.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51726. MYST_HAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiMYST1_ORYSJ
AccessioniPrimary (citable) accession number: Q8LI34
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 1, 2002
Last modified: April 1, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.