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Q8LH82

- HXK1_ORYSJ

UniProt

Q8LH82 - HXK1_ORYSJ

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Protein

Hexokinase-1

Gene

HXK1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Fructose and glucose phosphorylating enzyme.1 Publication

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi106 – 1116ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.1.1. 4460.

Names & Taxonomyi

Protein namesi
Recommended name:
Hexokinase-1 (EC:2.7.1.1)
Gene namesi
Name:HXK1
Ordered Locus Names:Os07g0446800, LOC_Os07g26540
ORF Names:P0030H06.133, P0475E07.113
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 7

Organism-specific databases

GrameneiQ8LH82.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 498498Hexokinase-1PRO_0000247564Add
BLAST

Proteomic databases

PRIDEiQ8LH82.

Expressioni

Gene expression databases

ExpressionAtlasiQ8LH82. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os07g26540.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LH82.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 245204Hexokinase type-1Add
BLAST
Domaini254 – 493240Hexokinase type-2Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni176 – 20227Glucose-bindingSequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 7574Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.Curated
Contains 1 hexokinase type-1 domain.Curated
Contains 1 hexokinase type-2 domain.Curated

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
InParanoidiQ8LH82.
KOiK00844.
OMAiGENICHL.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

Q8LH82-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAAAVAADQ KVVTMTSLRE GCACAAPPAA AAPPMPKMAA AQRVVAELRE
60 70 80 90 100
ACATPAARLA EVAAAMAGEM EAGLAVEGGS SEMKMIVSYV DSLPTGGEEG
110 120 130 140 150
SYYALDLGGT NFRVLRVRLA GGGVAERVAR EVPIPPGLMS GGGATSECLF
160 170 180 190 200
GFIASALAEF VGEEEEEGGL DGGERELGFT FSFPVHQTSI ASGTLIRWTK
210 220 230 240 250
AFAVDDAIGE DVVAALQAAM SERGLDMRVS ALINDTVGTL AAGSYYDEDV
260 270 280 290 300
VAAVILGTGT NAAYVEDATA IAKLHPSQLP ASNTMVINTE WGSFASPCLP
310 320 330 340 350
LTEFDEALDQ ESLNPGEQTY EKLISGMYLG EIVRRVLLKI SSRCPSLLGG
360 370 380 390 400
AGELATPFVL RTPDVSAMHH DETPDLSIVG EKLERTLGIR GTSPEARRMV
410 420 430 440 450
VEVCDIVATR AARLAAAGIV GILKKIGRVD GGEGRRRRSV VAVDGGLFEH
460 470 480 490
YGKFRRCMES AVRELLGEAA AERVVVKLAS DGSGLGAALV AAAHSQRA
Length:498
Mass (Da):51,772
Last modified:October 1, 2002 - v1
Checksum:i6DC7BD48B62C985E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ116383 mRNA. Translation: AAZ93618.1.
AY884164 mRNA. Translation: AAX68417.1.
AP004395 Genomic DNA. Translation: BAC10209.1.
AP004668 Genomic DNA. Translation: BAC16101.1.
RefSeqiNP_001059538.1. NM_001066073.1.
UniGeneiOs.89976.

Genome annotation databases

EnsemblPlantsiOS07T0446800-00; OS07T0446800-00; OS07G0446800.
GeneIDi4343113.
KEGGiosa:4343113.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ116383 mRNA. Translation: AAZ93618.1 .
AY884164 mRNA. Translation: AAX68417.1 .
AP004395 Genomic DNA. Translation: BAC10209.1 .
AP004668 Genomic DNA. Translation: BAC16101.1 .
RefSeqi NP_001059538.1. NM_001066073.1.
UniGenei Os.89976.

3D structure databases

ProteinModelPortali Q8LH82.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os07g26540.1.

Proteomic databases

PRIDEi Q8LH82.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS07T0446800-00 ; OS07T0446800-00 ; OS07G0446800 .
GeneIDi 4343113.
KEGGi osa:4343113.

Organism-specific databases

Gramenei Q8LH82.

Phylogenomic databases

eggNOGi COG5026.
HOGENOMi HOG000162670.
InParanoidi Q8LH82.
KOi K00844.
OMAi GENICHL.

Enzyme and pathway databases

BRENDAi 2.7.1.1. 4460.

Gene expression databases

ExpressionAtlasi Q8LH82. baseline.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.)."
    Cho J.-I., Ryoo N., Ko S., Lee S.-K., Lee J., Jung K.-H., Lee Y.-H., Bhoo S.H., Winderickx J., An G., Hahn T.-R., Jeon J.-S.
    Planta 224:598-611(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, NOMENCLATURE.
    Strain: cv. Jinmi.
  2. "The hexokinase gene family in rice."
    Wang Y.D., Cheng W., Wang X.S., Zhou X.J.
    Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Zhonghua 15.
    Tissue: Flower.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiHXK1_ORYSJ
AccessioniPrimary (citable) accession number: Q8LH82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3