Q8LGI2 (SCPDL_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable mitochondrial saccharopine dehydrogenase-like oxidoreductase At5g39410
Short name=SDH
EC=1.-.-.-

Gene names

Ordered Locus Names:	At5g39410
ORF Names:	MUL8.9

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	454 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion membrane Ref.5 Ref.6.
Sequence similarities	Belongs to the saccharopine dehydrogenase family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	chloroplast envelope Inferred from direct assay. Source: TAIR mitochondrial membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from direct assay. Source: TAIR vacuolar membrane Inferred from direct assay. Source: TAIR
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 454	454	Probable mitochondrial saccharopine dehydrogenase-like oxidoreductase At5g39410		PRO_0000226069
Experimental info
	Sequence conflict	8	1	E → D in AAM60851. Ref.4
	Sequence conflict	13	1	M → I in AAM60851. Ref.4
	Sequence conflict	38	1	Missing Ref.4
	Sequence conflict	136	1	N → K in AAM60851. Ref.4
	Sequence conflict	403	1	V → L in AAM60851. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q8LGI2 [UniParc]. Last modified March 7, 2006. Version 2. Checksum: 7020142459682B6B	FASTA	454	49,681
	10 20 30 40 50 60 MNPTQKPEPV YDMVILGASG FTGKYVVREA LKFLQTPSSS PLKSLALAGR NPTRLTQSLE 70 80 90 100 110 120 WAARPNPPPS SVAILTADTS DPDSLRRLCT QTKLILNCVG PFRIHGDPVV SACADSGCDY 130 140 150 160 170 180 LDISGEPEFM ERMEANYHDR AEETGSLIVS ACGFDSIPAE LGLLFNAKQW VSPSVPNQIE 190 200 210 220 230 240 AYLSLESDKK IAGNFGTYES AVLGVANAEK LKELRRSRPR RPRPTICGPP AKGPTLENQK 250 260 270 280 290 300 TIGLWALKLP SADAVVVRRT LTTLTEKPHG LPGINESPEQ IQKREAFWSS IKPAHFGVKI 310 320 330 340 350 360 TSKSLFGIFR YVTLGVSLGL LSKFSFGRWL LLKFPSVFSL GWFQKKGPSE EEVESATFKM 370 380 390 400 410 420 WFIGRGYSEE SLASQGETKP DLEIITRISG PEIGYITTPI TLVQCGLIVL GQRESLVKGG 430 440 450 VYTPGIVFGS TDIQQRLEDN GISFELISKI KTQG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Lessard P., Petit-Jean X., Kreis M., Thomas M. Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones." Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., Tabata S. DNA Res. 5:41-54(1998) [PubMed: 9628582] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]	"The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions." Brugiere S., Kowalski S., Ferro M., Seigneurin-Berny D., Miras S., Salvi D., Ravanel S., d'Herin P., Garin J., Bourguignon J., Joyard J., Rolland N. Phytochemistry 65:1693-1707(2004) [PubMed: 15276431] [Abstract] Cited for: SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY.
[6]	"Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins." Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J., Millar A.H. Plant Cell 16:241-256(2004) [PubMed: 14671022] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. Strain: cv. Landsberg erecta.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U83179 mRNA. Translation: AAD09232.1. AB009054 Genomic DNA. Translation: BAB11014.1. CP002688 Genomic DNA. Translation: AED94430.1. AY084257 mRNA. Translation: AAM60851.1.
IPI	IPI00529205.
RefSeq	NP_568564.1. NM_123303.3.
UniGene	At.30348. At.49110.
3D structure databases
ProteinModelPortal	Q8LGI2.
SMR	Q8LGI2. Positions 13-101.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8LGI2.
Proteomic databases
PRIDE	Q8LGI2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G39410.1; AT5G39410.1; AT5G39410.
GeneID	833937.
GenomeReviews	Gene locus AT5G39410 in contig BA000015_GR.
KEGG	ath:AT5G39410.
NMPDR	fig|3702.1.peg.25637.
Organism-specific databases
TAIR	At5g39410.
Phylogenomic databases
GeneTree	EPGT00050000019743.
HOGENOM	HBG527018.
InParanoid	Q8LGI2.
OMA	LMYWKYH.
PhylomeDB	Q8LGI2.
ProtClustDB	CLSN2689898.
Gene expression databases
Genevestigator	Q8LGI2.
GermOnline	AT5G39410. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR016040. NAD(P)-bd_dom. IPR005097. Saccharopine_DH/HSpermid_syn. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF03435. Saccharop_dh. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCPDL_ARATH

Accession

Primary (citable) accession number: Q8LGI2
Secondary accession number(s): Q9ZR98

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program