Unreviewed, UniProtKB/TrEMBL Q8LGH4 (Q8LGH4_ARATH)

Names and origin

Protein names	Submitted name:     Cullin EMBL AAM60859.1
Organism	Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier	3702 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	792 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the cullin family. RuleBase RU003829V0

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from mutant phenotype. Source: TAIR cotyledon development Inferred from mutant phenotype. Source: TAIR flower development Inferred from mutant phenotype. Source: TAIR fruit development Inferred from mutant phenotype. Source: TAIR hormone-mediated signaling Inferred from mutant phenotype. Source: TAIR leaf development Inferred from mutant phenotype. Source: TAIR negative regulation of photomorphogenesis Inferred from mutant phenotype. Source: TAIR protein polyubiquitination Inferred from direct assay. Source: TAIR sugar mediated signaling Inferred from mutant phenotype. Source: TAIR ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	CUL4 RING ubiquitin ligase complex Inferred from physical interaction. Source: TAIR nucleus Inferred from direct assay. Source: TAIR
Molecular function	ubiquitin protein ligase binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
DDB1A	Q9M0V3	1	EBI-1632927,EBI-1632780
PRL1	Q42384	1	EBI-1632927,EBI-1382964

Sequences

	Sequence		Length	Mass (Da)
	Q8LGH4-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 6C1E21BFCB9141DF	FASTA	792	91,471
	10 20 30 40 50 60 MSLPTKRSTF SAASASDDSS YSSPPMKKAK NDLHHSPQHP NTADKVVGFH MEEDPTPAAA 70 80 90 100 110 120 NLSRKKATLP QPTKKFVIKL NKAKPTLPTN FEENTWEKLQ SAIRAIFLKK KISFDLESLY 130 140 150 160 170 180 QAVDNLCLHK LDGKLYDQIE KECEEHISAA LQSLVGQNTD LTVFLSRVEK CWQDFCDQML 190 200 210 220 230 240 MIRSIALTLD RKYVIQNPNV RSLWEMGLQL FRKHLSLAPE VEQRTVKGLL SMIEKERLAE 250 260 270 280 290 300 AVNRTLLSHL LKMFTALGIY MESFEKPFLE GTSEFYAAEG MKYMQQSDVP EYLKHVEGRL 310 320 330 340 350 360 HEENERCILY IDAVTRKPLI TTVERQLLER HILVVLEKGF TTLMDGRRTE DLQRMQTLFS 370 380 390 400 410 420 RVNALESLRQ ALSSYVRKTG QKIVMDEEKD KDMVQSLLDF KASLDIIWEE SFYKNESFGN 430 440 450 460 470 480 TIKDSFEHLI NLRQNRPAEL IAKFLDEKLR AGNKGTSEEE LESVLEKVLV LFRFIQGKDV 490 500 510 520 530 540 FEAFYKKDLA KRLLLGKSAS IDAEKSMISK LKTECGSQFT NKLEGMFKDI ELSKEINESF 550 560 570 580 590 600 KQSSQARTKL PSGIEMSVHV LTTGYWPTYP PMDVKLPHEL NVYQDIFKEF YLSKYSGRRL 610 620 630 640 650 660 MWQNSLGHCV LKADFSKGKK ELAVSLFQAV VLMLFNDAMK LSFEDIKDST SIEDKELRRT 670 680 690 700 710 720 LQSLACGKVR VLQKNPKGRD VEDGDEFEFN DEFAAPLYRI KVNAIQMKET VEENTSTTER 730 740 750 760 770 780 VFQDRQYQID AAIVRIMKTR KVLSHTLLIT ELFQQLKFPI KPADLKKRIE SLIDREYLER 790 EKSNPQIYNY LA

References

[1]	"Full-length messenger RNA sequences greatly improve genome annotation." Haas B.J., Volfovsky N., Town C.D., Troukhan M., Alexandrov N., Feldmann K.A., Flavell R.B., White O., Salzberg S.L. Genome Biol. 3:RESEARCH0029-RESEARCH0029(2002) [PubMed: 12093376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Features of Arabidopsis genes and genome discovered using full-length cDNAs." Alexandrov N.A., Troukhan M.E., Brover V.V., Flavell R.B., Feldmann K.A. Plant Mol. Biol. 60:71-87(2006) Cited for: NUCLEOTIDE SEQUENCE.
[3]	Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R., Feldmann K. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY084267 mRNA. Translation: AAM60859.1.
IPI	IPI00538554.
RefSeq	NP_568658.1.
UniGene	At.20972
3D structure databases
HSSP	HSSP built from PDB template 1IUY based on UniProtKB Q9JLV5.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8LGH4. 3 interactions.
Proteomic databases
PRIDE	Q8LGH4.
Genome annotation databases
GeneID	834663.
KEGG	ath:AT5G46210.
NMPDR	fig|3702.1.peg.26410.
Organism-specific databases
TAIR	At5g46210.
Phylogenomic databases
OMA	Q8LGH4. ERIFCSS.
Family and domain databases
InterPro	IPR016157. Cullin_CS. IPR016158. Cullin_homology. IPR001373. Cullin_N. IPR019559. Cullin_neddylation_domain. IPR011991. Wing_hlx_DNA_bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF00888. Cullin. 1 hit. PF10557. Cullin_Nedd8. 1 hit. [Graphical view]
SMART	SM00182. CULLIN. 1 hit. [Graphical view]
PROSITE	PS01256. CULLIN_1. 1 hit. PS50069. CULLIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8LGH4_ARATH

Accession

Primary (citable) accession number: Q8LGH4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)