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Q8LG70 (6PGL2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 6-phosphogluconolactonase 2
Short name=6PGL 2
EC=3.1.1.31
Gene names
Ordered Locus Names:At3g49360
ORF Names:F2K15.220, T1G12.6
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.

Sequence similarities

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Cellular componentvacuolar membrane

Inferred from direct assay. Source: TAIR

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Probable 6-phosphogluconolactonase 2
PRO_0000288669

Experimental info

Sequence conflict351G → E in AAM61007. Ref.4
Sequence conflict421S → Y in AAM61007. Ref.4
Sequence conflict991V → I in AAM61007. Ref.4
Sequence conflict1081D → N in AAM61007. Ref.4
Sequence conflict1941L → F in AAM61007. Ref.4
Sequence conflict2181V → A in AAM61007. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q8LG70 [UniParc].

Last modified May 29, 2007. Version 2.
Checksum: DA9C421E48BC0CA6

FASTA25928,863
        10         20         30         40         50         60 
MAPVKRRVFK TNNEMAVELA KYTADLSSKF CKERGVFTVV LSGGDLIAWL WKLLEAPYID 

        70         80         90        100        110        120 
SIEWSKWHIF WVDERVCAWD HADSNYKLAY DGFLSKVPVP AENIYAIDNG LGAEGNAELA 

       130        140        150        160        170        180 
AERYEECLKQ KVNQNIIRTY KSSGFPQFDL QLLGMGPDGH MASLFPGHAQ INEKVKWVTS 

       190        200        210        220        230        240 
ITDSPKPPSK RITLTLPVIN CASYNVMAVC DKEQADSVAA ALNHTKDLPA GRLTADVEVV 

       250 
WFLDQAAASK LPHGWCSIL

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed: 11130713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed: 11910074] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Arabidopsis ORF clones."
Shinn P., Chen H., Kim C.J., Ecker J.R.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC012329 Genomic DNA. Translation: AAG52194.1.
AL132956 Genomic DNA. Translation: CAB66415.1.
CP002686 Genomic DNA. Translation: AEE78532.1.
AK117146 mRNA. Translation: BAC41824.1.
AY084434 mRNA. Translation: AAM61007.1.
BT024902 mRNA. Translation: ABD91493.1.
IPIIPI00526858.
PIRT45841.
RefSeqNP_190505.1. NM_114796.3.
UniGeneAt.43224.

3D structure databases

ProteinModelPortalQ8LG70.
SMRQ8LG70. Positions 2-251.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8LG70.

Proteomic databases

PRIDEQ8LG70.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G49360.1; AT3G49360.1; AT3G49360.
GeneID824098.
GenomeReviewsGene locus AT3G49360 in contig BA000014_GR.
KEGGath:AT3G49360.
NMPDRfig|3702.1.peg.16183.

Organism-specific databases

TAIRAt3g49360.

Phylogenomic databases

eggNOGKOG3147.
GeneTreeEPGT00070000028573.
HOGENOMHBG725991.
InParanoidQ8LG70.
OMAENIYAID.
PhylomeDBQ8LG70.
ProtClustDBCLSN2684237.

Gene expression databases

GenevestigatorQ8LG70.

Family and domain databases

InterProIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
KOK01057.
PfamPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsTIGR01198. Pgl. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL2_ARATH
AccessionPrimary (citable) accession number: Q8LG70
Secondary accession number(s): Q9SG13
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: November 16, 2011
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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