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Protein

Cyclic dof factor 3

Gene

CDF3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression.By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • DNA binding transcription factor activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • flower development Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processFlowering, Transcription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclic dof factor 3
Alternative name(s):
Dof zinc finger protein DOF3.3
Short name:
AtDOF3.3
H-protein promoter-binding factor 2a
Gene namesi
Name:CDF3
Synonyms:DOF3.3, HPPBF-2A
Ordered Locus Names:At3g47500
ORF Names:F1P2.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G47500
TAIRilocus:2079152 AT3G47500

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No alteration in flowering time, probably due to the redundancy with CDF1, CDF2 and CDF5.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000742791 – 448Cyclic dof factor 3Add BLAST448

Proteomic databases

PaxDbiQ8LFV3

PTM databases

iPTMnetiQ8LFV3

Expressioni

Tissue specificityi

Expressed in the vasculature of cotyledons and hypocotyls, leaves and roots.1 Publication

Inductioni

Circadian-regulation. Highly expressed at the beginning of the light period, then decreases, reaching a minimum between 16 and 29 hours after dawn before rising again at the end of the day.1 Publication

Gene expression databases

ExpressionAtlasiQ8LFV3 baseline and differential
GenevisibleiQ8LFV3 AT

Interactioni

Subunit structurei

Interacts with ADO2 (via kelch repeats) and ADO3 (via kelch repeats).1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi9224, 2 interactors
IntActiQ8LFV3, 2 interactors
STRINGi3702.AT3G47500.1

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi291 – 329Pro-richAdd BLAST39

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IIJ7 Eukaryota
ENOG410YN7N LUCA
HOGENOMiHOG000239772
InParanoidiQ8LFV3
OMAiNHSVDES
OrthoDBiEOG0936092V
PhylomeDBiQ8LFV3

Family and domain databases

InterProiView protein in InterPro
IPR003851 Znf_Dof
PfamiView protein in Pfam
PF02701 zf-Dof, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007478 Znf_Dof, 1 hit
PROSITEiView protein in PROSITE
PS01361 ZF_DOF_1, 1 hit
PS50884 ZF_DOF_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8LFV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMMETRDPAI KLFGMKIPFP SVFESAVTVE DDEEDDWSGG DDKSPEKVTP
60 70 80 90 100
ELSDKNNNNC NDNSFNNSKP ETLDKEEATS TDQIESSDTP EDNQQTTPDG
110 120 130 140 150
KTLKKPTKIL PCPRCKSMET KFCYYNNYNI NQPRHFCKAC QRYWTAGGTM
160 170 180 190 200
RNVPVGAGRR KNKSSSSHYR HITISEALEA ARLDPGLQAN TRVLSFGLEA
210 220 230 240 250
QQQHVAAPMT PVMKLQEDQK VSNGARNRFH GLADQRLVAR VENGDDCSSG
260 270 280 290 300
SSVTTSNNHS VDESRAQSGS VVEAQMNNNN NNNMNGYACI PGVPWPYTWN
310 320 330 340 350
PAMPPPGFYP PPGYPMPFYP YWTIPMLPPH QSSSPISQKC SNTNSPTLGK
360 370 380 390 400
HPRDEGSSKK DNETERKQKA GCVLVPKTLR IDDPNEAAKS SIWTTLGIKN
410 420 430 440
EAMCKAGGMF KGFDHKTKMY NNDKAENSPV LSANPAALSR SHNFHEQI
Length:448
Mass (Da):49,730
Last modified:October 25, 2004 - v2
Checksum:i6E61FA7A7A8DF1F6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti88D → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti201Q → H in AAM61191 (Ref. 5) Curated1
Sequence conflicti206Missing in AAM61191 (Ref. 5) Curated1
Sequence conflicti210T → A in AAM61191 (Ref. 5) Curated1
Sequence conflicti217E → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti228R → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti270 – 271SV → RI in AAM61191 (Ref. 5) Curated2
Sequence conflicti274A → P in AAM61191 (Ref. 5) Curated1
Sequence conflicti277 – 278Missing in AAM61191 (Ref. 5) Curated2
Sequence conflicti327 – 328LP → ISPS in AAM61191 (Ref. 5) Curated2
Sequence conflicti340C → D in AAM61191 (Ref. 5) Curated1
Sequence conflicti351 – 352HP → RS in AAM61191 (Ref. 5) Curated2
Sequence conflicti356G → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti360 – 362KDN → RDS in AAM61191 (Ref. 5) Curated3
Sequence conflicti369 – 370KA → RT in AAM61191 (Ref. 5) Curated2
Sequence conflicti373V → I in AAM61191 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079503 mRNA Translation: AAC28390.1
AL132955 Genomic DNA Translation: CAB61976.1
CP002686 Genomic DNA Translation: AEE78290.1
AY065152 mRNA Translation: AAL38328.1
AY128757 mRNA Translation: AAM91157.1
AY084628 mRNA Translation: AAM61191.1
PIRiT45710
RefSeqiNP_190334.1, NM_114618.4
UniGeneiAt.519

Genome annotation databases

EnsemblPlantsiAT3G47500.1; AT3G47500.1; AT3G47500
GeneIDi823904
GrameneiAT3G47500.1; AT3G47500.1; AT3G47500
KEGGiath:AT3G47500

Similar proteinsi

Entry informationi

Entry nameiCDF3_ARATH
AccessioniPrimary (citable) accession number: Q8LFV3
Secondary accession number(s): O81600
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: October 25, 2004
Last modified: April 25, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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