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Protein

Cyclic dof factor 3

Gene

CDF3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression.By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • metal ion binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • flower development Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processFlowering, Transcription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclic dof factor 3
Alternative name(s):
Dof zinc finger protein DOF3.3
Short name:
AtDOF3.3
H-protein promoter-binding factor 2a
Gene namesi
Name:CDF3
Synonyms:DOF3.3, HPPBF-2A
Ordered Locus Names:At3g47500
ORF Names:F1P2.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRilocus:2079152. AT3G47500.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No alteration in flowering time, probably due to the redundancy with CDF1, CDF2 and CDF5.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000742791 – 448Cyclic dof factor 3Add BLAST448

Proteomic databases

PaxDbiQ8LFV3.

PTM databases

iPTMnetiQ8LFV3.

Expressioni

Tissue specificityi

Expressed in the vasculature of cotyledons and hypocotyls, leaves and roots.1 Publication

Inductioni

Circadian-regulation. Highly expressed at the beginning of the light period, then decreases, reaching a minimum between 16 and 29 hours after dawn before rising again at the end of the day.1 Publication

Gene expression databases

GenevisibleiQ8LFV3. AT.

Interactioni

Subunit structurei

Interacts with ADO2 (via kelch repeats) and ADO3 (via kelch repeats).1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi9224. 2 interactors.
IntActiQ8LFV3. 2 interactors.
STRINGi3702.AT3G47500.1.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi291 – 329Pro-richAdd BLAST39

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri110 – 164Dof-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IIJ7. Eukaryota.
ENOG410YN7N. LUCA.
HOGENOMiHOG000239772.
InParanoidiQ8LFV3.
OrthoDBiEOG0936092V.
PhylomeDBiQ8LFV3.

Family and domain databases

InterProiView protein in InterPro
IPR003851. Znf_Dof.
PfamiView protein in Pfam
PF02701. zf-Dof. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007478. Znf_Dof. 1 hit.
PROSITEiView protein in PROSITE
PS01361. ZF_DOF_1. 1 hit.
PS50884. ZF_DOF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8LFV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMMETRDPAI KLFGMKIPFP SVFESAVTVE DDEEDDWSGG DDKSPEKVTP
60 70 80 90 100
ELSDKNNNNC NDNSFNNSKP ETLDKEEATS TDQIESSDTP EDNQQTTPDG
110 120 130 140 150
KTLKKPTKIL PCPRCKSMET KFCYYNNYNI NQPRHFCKAC QRYWTAGGTM
160 170 180 190 200
RNVPVGAGRR KNKSSSSHYR HITISEALEA ARLDPGLQAN TRVLSFGLEA
210 220 230 240 250
QQQHVAAPMT PVMKLQEDQK VSNGARNRFH GLADQRLVAR VENGDDCSSG
260 270 280 290 300
SSVTTSNNHS VDESRAQSGS VVEAQMNNNN NNNMNGYACI PGVPWPYTWN
310 320 330 340 350
PAMPPPGFYP PPGYPMPFYP YWTIPMLPPH QSSSPISQKC SNTNSPTLGK
360 370 380 390 400
HPRDEGSSKK DNETERKQKA GCVLVPKTLR IDDPNEAAKS SIWTTLGIKN
410 420 430 440
EAMCKAGGMF KGFDHKTKMY NNDKAENSPV LSANPAALSR SHNFHEQI
Length:448
Mass (Da):49,730
Last modified:October 25, 2004 - v2
Checksum:i6E61FA7A7A8DF1F6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti88D → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti201Q → H in AAM61191 (Ref. 5) Curated1
Sequence conflicti206Missing in AAM61191 (Ref. 5) Curated1
Sequence conflicti210T → A in AAM61191 (Ref. 5) Curated1
Sequence conflicti217E → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti228R → G in AAM61191 (Ref. 5) Curated1
Sequence conflicti270 – 271SV → RI in AAM61191 (Ref. 5) Curated2
Sequence conflicti274A → P in AAM61191 (Ref. 5) Curated1
Sequence conflicti277 – 278Missing in AAM61191 (Ref. 5) Curated2
Sequence conflicti327 – 328LP → ISPS in AAM61191 (Ref. 5) Curated2
Sequence conflicti340C → D in AAM61191 (Ref. 5) Curated1
Sequence conflicti351 – 352HP → RS in AAM61191 (Ref. 5) Curated2
Sequence conflicti356G → E in AAM61191 (Ref. 5) Curated1
Sequence conflicti360 – 362KDN → RDS in AAM61191 (Ref. 5) Curated3
Sequence conflicti369 – 370KA → RT in AAM61191 (Ref. 5) Curated2
Sequence conflicti373V → I in AAM61191 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079503 mRNA. Translation: AAC28390.1.
AL132955 Genomic DNA. Translation: CAB61976.1.
CP002686 Genomic DNA. Translation: AEE78290.1.
AY065152 mRNA. Translation: AAL38328.1.
AY128757 mRNA. Translation: AAM91157.1.
AY084628 mRNA. Translation: AAM61191.1.
PIRiT45710.
RefSeqiNP_190334.1. NM_114618.4.
UniGeneiAt.519.

Genome annotation databases

EnsemblPlantsiAT3G47500.1; AT3G47500.1; AT3G47500.
GeneIDi823904.
GrameneiAT3G47500.1; AT3G47500.1; AT3G47500.
KEGGiath:AT3G47500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079503 mRNA. Translation: AAC28390.1.
AL132955 Genomic DNA. Translation: CAB61976.1.
CP002686 Genomic DNA. Translation: AEE78290.1.
AY065152 mRNA. Translation: AAL38328.1.
AY128757 mRNA. Translation: AAM91157.1.
AY084628 mRNA. Translation: AAM61191.1.
PIRiT45710.
RefSeqiNP_190334.1. NM_114618.4.
UniGeneiAt.519.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi9224. 2 interactors.
IntActiQ8LFV3. 2 interactors.
STRINGi3702.AT3G47500.1.

PTM databases

iPTMnetiQ8LFV3.

Proteomic databases

PaxDbiQ8LFV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G47500.1; AT3G47500.1; AT3G47500.
GeneIDi823904.
GrameneiAT3G47500.1; AT3G47500.1; AT3G47500.
KEGGiath:AT3G47500.

Organism-specific databases

AraportiAT3G47500.
TAIRilocus:2079152. AT3G47500.

Phylogenomic databases

eggNOGiENOG410IIJ7. Eukaryota.
ENOG410YN7N. LUCA.
HOGENOMiHOG000239772.
InParanoidiQ8LFV3.
OrthoDBiEOG0936092V.
PhylomeDBiQ8LFV3.

Miscellaneous databases

PROiPR:Q8LFV3.

Gene expression databases

GenevisibleiQ8LFV3. AT.

Family and domain databases

InterProiView protein in InterPro
IPR003851. Znf_Dof.
PfamiView protein in Pfam
PF02701. zf-Dof. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007478. Znf_Dof. 1 hit.
PROSITEiView protein in PROSITE
PS01361. ZF_DOF_1. 1 hit.
PS50884. ZF_DOF_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCDF3_ARATH
AccessioniPrimary (citable) accession number: Q8LFV3
Secondary accession number(s): O81600
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: October 25, 2004
Last modified: April 12, 2017
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.