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Protein

Probable xyloglucan endotransglucosylase/hydrolase protein 6

Gene

XTH6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).By similarity

Catalytic activityi

Breaks a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei110NucleophilePROSITE-ProRule annotation1
Active sitei114Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase, Transferase

Keywords - Biological processi

Cell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciARA:AT5G65730-MONOMER.

Protein family/group databases

CAZyiGH16. Glycoside Hydrolase Family 16.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable xyloglucan endotransglucosylase/hydrolase protein 6 (EC:2.4.1.207)
Short name:
At-XTH6
Short name:
XTH-6
Gene namesi
Name:XTH6
Synonyms:XTR10
Ordered Locus Names:At5g65730
ORF Names:MPA24.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G65730.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_000001180631 – 292Probable xyloglucan endotransglucosylase/hydrolase protein 6Add BLAST262

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi118N-linked (GlcNAc...)Sequence analysis1

Post-translational modificationi

Contains at least one intrachain disulfide bond essential for its enzymatic activity.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8LF99.

Expressioni

Gene expression databases

ExpressionAtlasiQ8LF99. baseline and differential.
GenevisibleiQ8LF99. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G65730.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LF99.
SMRiQ8LF99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 224GH16PROSITE-ProRule annotationAdd BLAST194

Sequence similaritiesi

Contains 1 GH16 (glycosyl hydrolase family 16) domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IKHW. Eukaryota.
COG2273. LUCA.
HOGENOMiHOG000236368.
InParanoidiQ8LF99.
KOiK08235.
OMAiQTNIFAH.
OrthoDBiEOG09360FZG.
PhylomeDBiQ8LF99.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000757. GH16.
IPR008263. GH16_AS.
IPR010713. XET_C.
IPR016455. XTH.
[Graphical view]
PfamiPF00722. Glyco_hydro_16. 1 hit.
PF06955. XET_C. 1 hit.
[Graphical view]
PIRSFiPIRSF005604. XET. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS01034. GH16_1. 1 hit.
PS51762. GH16_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8LF99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIYSPSFP GTLCLCIFTL LTLMFIRVSA RPATFVEDFK AAWSESHIRQ
60 70 80 90 100
MEDGKAIQLV LDQSTGCGFA SKRKYLFGRV SMKIKLIPGD SAGTVTAFYM
110 120 130 140 150
NSDTATVRDE LDFEFLGNRS GQPYSVQTNI FAHGKGDREQ RVNLWFDPSM
160 170 180 190 200
DYHTYTILWS HKHIVFYVDD VPIREYKNNE AKNIAYPTSQ PMGVYSTLWE
210 220 230 240 250
ADDWATRGGL EKIDWSKAPF YAYYKDFDIE GCPVPGPTFC PSNPHNWWEG
260 270 280 290
YAYQSLNAVE ARRYRWVRVN HMVYDYCTDR SRFPVPPPEC RA
Length:292
Mass (Da):33,692
Last modified:November 28, 2003 - v2
Checksum:i325CD353A5694144
GO

Sequence cautioni

The sequence BAB10680 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAA16685 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti83K → R in AAM61529 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010075 Genomic DNA. Translation: BAB10680.1. Different initiation.
AL021684 Genomic DNA. Translation: CAA16685.1. Different initiation.
CP002688 Genomic DNA. Translation: AED98096.1.
AY044329 mRNA. Translation: AAK73270.1.
AY057564 mRNA. Translation: AAL09803.1.
AY093983 mRNA. Translation: AAM16244.1.
AY084968 mRNA. Translation: AAM61529.1.
PIRiT05895.
RefSeqiNP_569019.1. NM_125970.4.
UniGeneiAt.23387.

Genome annotation databases

EnsemblPlantsiAT5G65730.1; AT5G65730.1; AT5G65730.
GeneIDi836702.
GrameneiAT5G65730.1; AT5G65730.1; AT5G65730.
KEGGiath:AT5G65730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010075 Genomic DNA. Translation: BAB10680.1. Different initiation.
AL021684 Genomic DNA. Translation: CAA16685.1. Different initiation.
CP002688 Genomic DNA. Translation: AED98096.1.
AY044329 mRNA. Translation: AAK73270.1.
AY057564 mRNA. Translation: AAL09803.1.
AY093983 mRNA. Translation: AAM16244.1.
AY084968 mRNA. Translation: AAM61529.1.
PIRiT05895.
RefSeqiNP_569019.1. NM_125970.4.
UniGeneiAt.23387.

3D structure databases

ProteinModelPortaliQ8LF99.
SMRiQ8LF99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G65730.1.

Protein family/group databases

CAZyiGH16. Glycoside Hydrolase Family 16.

Proteomic databases

PaxDbiQ8LF99.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G65730.1; AT5G65730.1; AT5G65730.
GeneIDi836702.
GrameneiAT5G65730.1; AT5G65730.1; AT5G65730.
KEGGiath:AT5G65730.

Organism-specific databases

TAIRiAT5G65730.

Phylogenomic databases

eggNOGiENOG410IKHW. Eukaryota.
COG2273. LUCA.
HOGENOMiHOG000236368.
InParanoidiQ8LF99.
KOiK08235.
OMAiQTNIFAH.
OrthoDBiEOG09360FZG.
PhylomeDBiQ8LF99.

Enzyme and pathway databases

BioCyciARA:AT5G65730-MONOMER.

Miscellaneous databases

PROiQ8LF99.

Gene expression databases

ExpressionAtlasiQ8LF99. baseline and differential.
GenevisibleiQ8LF99. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000757. GH16.
IPR008263. GH16_AS.
IPR010713. XET_C.
IPR016455. XTH.
[Graphical view]
PfamiPF00722. Glyco_hydro_16. 1 hit.
PF06955. XET_C. 1 hit.
[Graphical view]
PIRSFiPIRSF005604. XET. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS01034. GH16_1. 1 hit.
PS51762. GH16_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiXTH6_ARATH
AccessioniPrimary (citable) accession number: Q8LF99
Secondary accession number(s): O49542, Q93ZF8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: November 28, 2003
Last modified: November 30, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.