Reviewed, UniProtKB/Swiss-Prot Q8LEV7 (6PGL3_ARATH)

Names and origin

Protein names

Recommended name:
    Probable 6-phosphogluconolactonase 3
      Short name=6PGL 3
    EC=3.1.1.31

Gene names

Ordered Locus Names:	At5g24420
ORF Names:	K16H17.13

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
Sequence similarities	Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 252	252	Probable 6-phosphogluconolactonase 3		PRO_0000288670
Experimental info
	Sequence conflict	65	1	P → S in AAM61753. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q8LEV7-1 [UniParc]. Last modified May 29, 2007. Version 2. Checksum: FAFEECE1F712FDA1	FASTA	252	28,476
	10 20 30 40 50 60 MAQRKMIVFP TKNELSEAMA EYTANLSAKF IKEKGLFTVV LSGGDLIDWL CKLVQPPYID 70 80 90 100 110 120 SIEWPKWHVF WVDERVCAWE DPDSNYKLAM EGFLSKVPIP DKNIYAIDKH LAADGNAEHC 130 140 150 160 170 180 ATLYEECLKN LVKEKIIPIS KKTGYPEFDL QLLGMGPDGH MASLFPNHPQ INEKQKWVTY 190 200 210 220 230 240 ITDSPKPPPK RITFTLPVIN STLYNLMAIC DKAPAKSVAE IMKHNNLSLP SAHLSAQVEN 250 VWYLDQAAAS EL

References

[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones." Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N., Tabata S. DNA Res. 5:379-391(1998) [PubMed: 10048488] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[3]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB016884 Genomic DNA. Translation: BAB11235.1. AF378879 mRNA. Translation: AAK55682.1. AY052737 mRNA. Translation: AAK96451.1. AY085203 mRNA. Translation: AAM61753.1.
IPI	IPI00533282.
RefSeq	NP_197830.1.
UniGene	At.8628
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8LEV7.
Proteomic databases
PRIDE	Q8LEV7.
Genome annotation databases
GeneID	832513.
GenomeReviews	Gene locus AT5G24420 in contig BA000015_GR.
KEGG	ath:AT5G24420.
NMPDR	fig|3702.1.peg.24634.
Organism-specific databases
TAIR	At5g24420.
Enzyme and pathway databases
BRENDA	3.1.1.31. 302.
Gene expression databases
Genevestigator	Q8LEV7.
Family and domain databases
InterPro	IPR005900. 6-phosphogluconolactonase. IPR006148. Glc/Gal-6P_isomerase. [Graphical view]
PANTHER	PTHR11054. Phosphogluconlac. 1 hit.
Pfam	PF01182. Glucosamine_iso. 1 hit. [Graphical view]
TIGRFAMs	TIGR01198. pgl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL3_ARATH

Accession

Primary (citable) accession number: Q8LEV7
Secondary accession number(s): Q9FIN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	October 13, 2009
This is version 34 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)