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Protein

Thioredoxin domain-containing protein PLP3B

Gene

PLP3B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Tubulin-binding protein involved in microtubule formation.1 Publication

GO - Molecular functioni

  • beta-tubulin binding Source: TAIR

GO - Biological processi

  • anisotropic cell growth Source: TAIR
  • cell redox homeostasis Source: InterPro
  • cortical microtubule organization Source: TAIR
  • cytokinesis by cell plate formation Source: TAIR
  • nuclear division Source: TAIR
  • nucleolus organization Source: TAIR
  • queuosine biosynthetic process Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin domain-containing protein PLP3B
Alternative name(s):
Phosducin-like protein 3B
Gene namesi
Name:PLP3B
Ordered Locus Names:At5g66410
ORF Names:K1F13.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G66410.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Microtubule, Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but plants with reduced levels of both PLP3A and PLP3B show defects in cytokinesis, cortical microtubule array formation, oriented cell growth, and maintenance of proper ploidy.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 230230Thioredoxin domain-containing protein PLP3BPRO_0000428877Add
BLAST

Proteomic databases

PaxDbiQ8LCV1.
PRIDEiQ8LCV1.

Expressioni

Tissue specificityi

Expressed in roots, cotyledons, leaves, stems and flowers.1 Publication

Gene expression databases

GenevisibleiQ8LCV1. AT.

Interactioni

Subunit structurei

Interacts with TUBB2, TUBB3, TUBB4 and TUBB5.By similarity

GO - Molecular functioni

  • beta-tubulin binding Source: TAIR

Protein-protein interaction databases

BioGridi22015. 2 interactions.
IntActiQ8LCV1. 2 interactions.
STRINGi3702.AT5G66410.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LCV1.
SMRiQ8LCV1. Positions 84-190.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini89 – 17385ThioredoxinAdd
BLAST

Sequence similaritiesi

Belongs to the phosducin family.Curated
Contains 1 thioredoxin domain.Curated

Phylogenomic databases

eggNOGiKOG1672. Eukaryota.
COG0526. LUCA.
HOGENOMiHOG000171916.
InParanoidiQ8LCV1.
OMAiTEKVICH.
OrthoDBiEOG09360OHG.
PhylomeDBiQ8LCV1.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8LCV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPDTVKSTL SNLAFGNVLA AAARDYKKEV LANEKAQGSR PVNEEVDLDE
60 70 80 90 100
LMDDPELEKL HADRIAALRR EVEKREAFKR QGHGEYREVS EGDFLGEVTR
110 120 130 140 150
SEKVICHFYH KEFYRCKIMD KHLKTLAPRH VDTKFIKMDA ENAPFFVTKL
160 170 180 190 200
AIKTLPCVIL FSKGIAMDRL VGFQDLGAKD DFSTTKLENL LVKKGMLSEK
210 220 230
RKEEDEEDYE YQESIRRSVR SSANVDSDSD
Length:230
Mass (Da):26,368
Last modified:October 1, 2002 - v1
Checksum:iA4DFE050A2679995
GO

Sequence cautioni

The sequence BAB10917 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013389 Genomic DNA. Translation: BAB10917.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED98210.1.
BT003998 mRNA. Translation: AAO42037.1.
BT005683 mRNA. Translation: AAO64103.1.
AY086393 mRNA. Translation: AAM64460.1.
RefSeqiNP_569033.1. NM_126039.3.
UniGeneiAt.28868.
At.8554.

Genome annotation databases

EnsemblPlantsiAT5G66410.1; AT5G66410.1; AT5G66410.
GeneIDi836773.
GrameneiAT5G66410.1; AT5G66410.1; AT5G66410.
KEGGiath:AT5G66410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013389 Genomic DNA. Translation: BAB10917.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED98210.1.
BT003998 mRNA. Translation: AAO42037.1.
BT005683 mRNA. Translation: AAO64103.1.
AY086393 mRNA. Translation: AAM64460.1.
RefSeqiNP_569033.1. NM_126039.3.
UniGeneiAt.28868.
At.8554.

3D structure databases

ProteinModelPortaliQ8LCV1.
SMRiQ8LCV1. Positions 84-190.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi22015. 2 interactions.
IntActiQ8LCV1. 2 interactions.
STRINGi3702.AT5G66410.1.

Proteomic databases

PaxDbiQ8LCV1.
PRIDEiQ8LCV1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G66410.1; AT5G66410.1; AT5G66410.
GeneIDi836773.
GrameneiAT5G66410.1; AT5G66410.1; AT5G66410.
KEGGiath:AT5G66410.

Organism-specific databases

TAIRiAT5G66410.

Phylogenomic databases

eggNOGiKOG1672. Eukaryota.
COG0526. LUCA.
HOGENOMiHOG000171916.
InParanoidiQ8LCV1.
OMAiTEKVICH.
OrthoDBiEOG09360OHG.
PhylomeDBiQ8LCV1.

Miscellaneous databases

PROiQ8LCV1.

Gene expression databases

GenevisibleiQ8LCV1. AT.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPLP3B_ARATH
AccessioniPrimary (citable) accession number: Q8LCV1
Secondary accession number(s): Q9FJZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.