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Protein

Thioredoxin domain-containing protein PLP3B

Gene

PLP3B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Tubulin-binding protein involved in microtubule formation.1 Publication

GO - Molecular functioni

  • beta-tubulin binding Source: TAIR

GO - Biological processi

  • anisotropic cell growth Source: TAIR
  • cell redox homeostasis Source: InterPro
  • cortical microtubule organization Source: TAIR
  • cytokinesis by cell plate formation Source: TAIR
  • nuclear division Source: TAIR
  • nucleolus organization Source: TAIR
  • queuosine biosynthetic process Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin domain-containing protein PLP3B
Alternative name(s):
Phosducin-like protein 3B
Gene namesi
Name:PLP3B
Ordered Locus Names:At5g66410
ORF Names:K1F13.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G66410
TAIRilocus:2154945 AT5G66410

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Microtubule, Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but plants with reduced levels of both PLP3A and PLP3B show defects in cytokinesis, cortical microtubule array formation, oriented cell growth, and maintenance of proper ploidy.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004288771 – 230Thioredoxin domain-containing protein PLP3BAdd BLAST230

Proteomic databases

PaxDbiQ8LCV1

Expressioni

Tissue specificityi

Expressed in roots, cotyledons, leaves, stems and flowers.1 Publication

Gene expression databases

ExpressionAtlasiQ8LCV1 baseline and differential
GenevisibleiQ8LCV1 AT

Interactioni

Subunit structurei

Interacts with TUBB2, TUBB3, TUBB4 and TUBB5.By similarity

GO - Molecular functioni

  • beta-tubulin binding Source: TAIR

Protein-protein interaction databases

BioGridi22015, 3 interactors
IntActiQ8LCV1, 2 interactors
STRINGi3702.AT5G66410.1

Structurei

3D structure databases

ProteinModelPortaliQ8LCV1
SMRiQ8LCV1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 173ThioredoxinAdd BLAST85

Sequence similaritiesi

Belongs to the phosducin family.Curated

Phylogenomic databases

eggNOGiKOG1672 Eukaryota
COG0526 LUCA
HOGENOMiHOG000171916
InParanoidiQ8LCV1
OMAiCHFFHRE
OrthoDBiEOG09360OHG
PhylomeDBiQ8LCV1

Family and domain databases

InterProiView protein in InterPro
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
PfamiView protein in Pfam
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit

Sequencei

Sequence statusi: Complete.

Q8LCV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPDTVKSTL SNLAFGNVLA AAARDYKKEV LANEKAQGSR PVNEEVDLDE
60 70 80 90 100
LMDDPELEKL HADRIAALRR EVEKREAFKR QGHGEYREVS EGDFLGEVTR
110 120 130 140 150
SEKVICHFYH KEFYRCKIMD KHLKTLAPRH VDTKFIKMDA ENAPFFVTKL
160 170 180 190 200
AIKTLPCVIL FSKGIAMDRL VGFQDLGAKD DFSTTKLENL LVKKGMLSEK
210 220 230
RKEEDEEDYE YQESIRRSVR SSANVDSDSD
Length:230
Mass (Da):26,368
Last modified:October 1, 2002 - v1
Checksum:iA4DFE050A2679995
GO

Sequence cautioni

The sequence BAB10917 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013389 Genomic DNA Translation: BAB10917.1 Sequence problems.
CP002688 Genomic DNA Translation: AED98210.1
BT003998 mRNA Translation: AAO42037.1
BT005683 mRNA Translation: AAO64103.1
AY086393 mRNA Translation: AAM64460.1
RefSeqiNP_569033.1, NM_126039.4
UniGeneiAt.28868
At.8554

Genome annotation databases

EnsemblPlantsiAT5G66410.1; AT5G66410.1; AT5G66410
GeneIDi836773
GrameneiAT5G66410.1; AT5G66410.1; AT5G66410
KEGGiath:AT5G66410

Similar proteinsi

Entry informationi

Entry nameiPLP3B_ARATH
AccessioniPrimary (citable) accession number: Q8LCV1
Secondary accession number(s): Q9FJZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: October 1, 2002
Last modified: April 25, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health