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Protein

Dehydrodolichyl diphosphate synthase 8

Gene

At5g60510

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.By similarity

Cofactori

Mg2+By similarity

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciARA:AT5G60510-MONOMER.
UniPathwayiUPA00378.

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydrodolichyl diphosphate synthase 8 (EC:2.5.1.-)
Short name:
Dedol-PP synthase 8
Gene namesi
Ordered Locus Names:At5g60510
ORF Names:MUF9.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G60510.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001237581 – 272Dehydrodolichyl diphosphate synthase 8Add BLAST272

Proteomic databases

PaxDbiQ8LAR7.

Expressioni

Gene expression databases

GenevisibleiQ8LAR7. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G60510.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LAR7.
SMRiQ8LAR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPP synthase family.Curated

Phylogenomic databases

eggNOGiKOG1602. Eukaryota.
COG0020. LUCA.
HOGENOMiHOG000006053.
InParanoidiQ8LAR7.
KOiK11778.
OMAiMNNTREE.
OrthoDBiEOG09360HR8.
PhylomeDBiQ8LAR7.

Family and domain databases

CDDicd00475. Cis_IPPS. 1 hit.
Gene3Di3.40.1180.10. 1 hit.
InterProiIPR001441. UPP_synth-like.
IPR018520. UPP_synth-like_CS.
[Graphical view]
PANTHERiPTHR10291. PTHR10291. 1 hit.
PfamiPF01255. Prenyltransf. 1 hit.
[Graphical view]
SUPFAMiSSF64005. SSF64005. 1 hit.
TIGRFAMsiTIGR00055. uppS. 1 hit.
PROSITEiPS01066. UPP_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8LAR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNTREEVGE FTQIFNALMS LMRKFIFKVL RVGPIPTNIS FIMDGNRRFA
60 70 80 90 100
KKRNLEGLDA GHRAGFISVK YILQYCKEIG VPYVTLYAFG MDNFKRGPEE
110 120 130 140 150
VKCVMDLMLE KVELTIDQAV SGNMNGVRII FAGDLNSLNE RFRAATKKLM
160 170 180 190 200
ELTEENRDLI VVVCVAYSTS VEIVHAVRDS CVRKSKTGDG SSALELSDIE
210 220 230 240 250
ECMYTSVVPV PDLVVRTGGG DRLSNFMTWQ TSRALLHRTE ALWPELGLWH
260 270
LVWAILKFQR MQDYLQKKKK LH
Length:272
Mass (Da):31,037
Last modified:September 13, 2005 - v2
Checksum:i3E601A4F0569F534
GO

Sequence cautioni

The sequence BAB08234 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti214V → M in AAM65193 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011483 Genomic DNA. Translation: BAB08234.1. Different initiation.
CP002688 Genomic DNA. Translation: AED97338.1.
AY087655 mRNA. Translation: AAM65193.1.
RefSeqiNP_200859.1. NM_125444.4.
UniGeneiAt.29156.
At.71243.

Genome annotation databases

EnsemblPlantsiAT5G60510.1; AT5G60510.1; AT5G60510.
GeneIDi836172.
GrameneiAT5G60510.1; AT5G60510.1; AT5G60510.
KEGGiath:AT5G60510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011483 Genomic DNA. Translation: BAB08234.1. Different initiation.
CP002688 Genomic DNA. Translation: AED97338.1.
AY087655 mRNA. Translation: AAM65193.1.
RefSeqiNP_200859.1. NM_125444.4.
UniGeneiAt.29156.
At.71243.

3D structure databases

ProteinModelPortaliQ8LAR7.
SMRiQ8LAR7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G60510.1.

Proteomic databases

PaxDbiQ8LAR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G60510.1; AT5G60510.1; AT5G60510.
GeneIDi836172.
GrameneiAT5G60510.1; AT5G60510.1; AT5G60510.
KEGGiath:AT5G60510.

Organism-specific databases

TAIRiAT5G60510.

Phylogenomic databases

eggNOGiKOG1602. Eukaryota.
COG0020. LUCA.
HOGENOMiHOG000006053.
InParanoidiQ8LAR7.
KOiK11778.
OMAiMNNTREE.
OrthoDBiEOG09360HR8.
PhylomeDBiQ8LAR7.

Enzyme and pathway databases

UniPathwayiUPA00378.
BioCyciARA:AT5G60510-MONOMER.

Miscellaneous databases

PROiQ8LAR7.

Gene expression databases

GenevisibleiQ8LAR7. AT.

Family and domain databases

CDDicd00475. Cis_IPPS. 1 hit.
Gene3Di3.40.1180.10. 1 hit.
InterProiIPR001441. UPP_synth-like.
IPR018520. UPP_synth-like_CS.
[Graphical view]
PANTHERiPTHR10291. PTHR10291. 1 hit.
PfamiPF01255. Prenyltransf. 1 hit.
[Graphical view]
SUPFAMiSSF64005. SSF64005. 1 hit.
TIGRFAMsiTIGR00055. uppS. 1 hit.
PROSITEiPS01066. UPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDDPS8_ARATH
AccessioniPrimary (citable) accession number: Q8LAR7
Secondary accession number(s): Q9FKJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.