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Protein

Dehydrodolichyl diphosphate synthase 8

Gene

At5g60510

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.By similarity

Cofactori

Mg2+By similarity

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyciARA:AT5G60510-MONOMER
UniPathwayiUPA00378

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydrodolichyl diphosphate synthase 8 (EC:2.5.1.-)
Short name:
Dedol-PP synthase 8
Gene namesi
Ordered Locus Names:At5g60510
ORF Names:MUF9.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G60510
TAIRilocus:2175183 AT5G60510

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001237581 – 272Dehydrodolichyl diphosphate synthase 8Add BLAST272

Proteomic databases

PaxDbiQ8LAR7
PRIDEiQ8LAR7

Expressioni

Gene expression databases

ExpressionAtlasiQ8LAR7 differential
GenevisibleiQ8LAR7 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G60510.1

Structurei

3D structure databases

ProteinModelPortaliQ8LAR7
SMRiQ8LAR7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPP synthase family.Curated

Phylogenomic databases

eggNOGiKOG1602 Eukaryota
COG0020 LUCA
HOGENOMiHOG000006053
InParanoidiQ8LAR7
KOiK11778
OMAiMTWQTSK
OrthoDBiEOG09360HR8
PhylomeDBiQ8LAR7

Family and domain databases

CDDicd00475 Cis_IPPS, 1 hit
Gene3Di3.40.1180.10, 1 hit
InterProiView protein in InterPro
IPR001441 UPP_synth-like
IPR018520 UPP_synth-like_CS
IPR036424 UPP_synth-like_sf
PANTHERiPTHR10291 PTHR10291, 1 hit
PfamiView protein in Pfam
PF01255 Prenyltransf, 1 hit
SUPFAMiSSF64005 SSF64005, 1 hit
TIGRFAMsiTIGR00055 uppS, 1 hit
PROSITEiView protein in PROSITE
PS01066 UPP_SYNTHASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8LAR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNTREEVGE FTQIFNALMS LMRKFIFKVL RVGPIPTNIS FIMDGNRRFA
60 70 80 90 100
KKRNLEGLDA GHRAGFISVK YILQYCKEIG VPYVTLYAFG MDNFKRGPEE
110 120 130 140 150
VKCVMDLMLE KVELTIDQAV SGNMNGVRII FAGDLNSLNE RFRAATKKLM
160 170 180 190 200
ELTEENRDLI VVVCVAYSTS VEIVHAVRDS CVRKSKTGDG SSALELSDIE
210 220 230 240 250
ECMYTSVVPV PDLVVRTGGG DRLSNFMTWQ TSRALLHRTE ALWPELGLWH
260 270
LVWAILKFQR MQDYLQKKKK LH
Length:272
Mass (Da):31,037
Last modified:September 13, 2005 - v2
Checksum:i3E601A4F0569F534
GO

Sequence cautioni

The sequence BAB08234 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti214V → M in AAM65193 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011483 Genomic DNA Translation: BAB08234.1 Different initiation.
CP002688 Genomic DNA Translation: AED97338.1
AY087655 mRNA Translation: AAM65193.1
RefSeqiNP_200859.1, NM_125444.4
UniGeneiAt.29156
At.71243

Genome annotation databases

EnsemblPlantsiAT5G60510.1; AT5G60510.1; AT5G60510
GeneIDi836172
GrameneiAT5G60510.1; AT5G60510.1; AT5G60510
KEGGiath:AT5G60510

Similar proteinsi

Entry informationi

Entry nameiDDPS8_ARATH
AccessioniPrimary (citable) accession number: Q8LAR7
Secondary accession number(s): Q9FKJ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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