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Protein

Dof zinc finger protein DOF4.6

Gene

DOF4.6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri53 – 107Dof-typePROSITE-ProRule annotationAdd BLAST55

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • metal ion binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • regulation of transcription, DNA-templated Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Dof zinc finger protein DOF4.6
Short name:
AtDOF4.6
Gene namesi
Name:DOF4.6
Ordered Locus Names:At4g24060
ORF Names:T19F6.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G24060.
TAIRilocus:2134981. AT4G24060.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000742891 – 342Dof zinc finger protein DOF4.6Add BLAST342

Proteomic databases

PaxDbiQ8LAP8.

Expressioni

Gene expression databases

ExpressionAtlasiQ8LAP8. baseline and differential.
GenevisibleiQ8LAP8. AT.

Interactioni

Protein-protein interaction databases

IntActiQ8LAP8. 1 interactor.
STRINGi3702.AT4G24060.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LAP8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi108 – 113Poly-Ser6
Compositional biasi181 – 223Asn-richAdd BLAST43

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri53 – 107Dof-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IWCF. Eukaryota.
ENOG410YH6N. LUCA.
HOGENOMiHOG000239394.
InParanoidiQ8LAP8.
OMAiVDINEHQ.
OrthoDBiEOG09360LOJ.
PhylomeDBiQ8LAP8.

Family and domain databases

InterProiView protein in InterPro
IPR003851. Znf_Dof.
PfamiView protein in Pfam
PF02701. zf-Dof. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007478. Znf_Dof. 1 hit.
PROSITEiView protein in PROSITE
PS01361. ZF_DOF_1. 1 hit.
PS50884. ZF_DOF_2. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8LAP8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDTAQWPQEI VVKPLEEIVT NTCPKPQPQP LQPQQPPSVG GERKARPEKD
60 70 80 90 100
QAVNCPRCNS TNTKFCYYNN YSLTQPRYFC KGCRRYWTEG GSLRNIPVGG
110 120 130 140 150
GSRKNKRSHS SSSDISNNHS DSTQPATKKH LSDHHHHLMS MSQQGLTGQN
160 170 180 190 200
PKFLETTQQD LNLGFSPHGM IRTNFTDLIH NIGNNTNKSN NNNNPLIVSS
210 220 230 240 250
CSAMATSSLD LIRNNSNNGN SSNSSFMGFP VHNQDPASGG FSMQDHYKPC
260 270 280 290 300
NTNTTLLGFS LDHHHNNGFH GGFQGGEEGG EGGDDVNGRH LFPFEDLKLP
310 320 330 340
VSSSSATINV DINEHQKRGS GSDAAATSGG YWTGMLSGGS WC
Length:342
Mass (Da):37,348
Last modified:November 9, 2004 - v2
Checksum:i8FAD64D9F18E7897
GO
Isoform 2 (identifier: Q8LAP8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-138: Missing.

Note: May be due to an intron retention. No experimental confirmation available.
Show »
Length:204
Mass (Da):21,740
Checksum:i9C580DB338F885D7
GO

Sequence cautioni

The sequence CAB51649 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB81324 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33P → T in AAM65223 (Ref. 4) Curated1
Sequence conflicti111S → F in AAM65223 (Ref. 4) Curated1
Sequence conflicti203A → T in AAM65223 (Ref. 4) Curated1
Sequence conflicti234Q → E in AAM65223 (Ref. 4) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0118691 – 138Missing in isoform 2. 1 PublicationAdd BLAST138

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002343 Genomic DNA. Translation: AAB63618.1.
AL109619 Genomic DNA. Translation: CAB51649.1. Sequence problems.
AL161560 Genomic DNA. Translation: CAB81324.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84846.1.
AY037220 mRNA. Translation: AAK59820.1.
BT008771 mRNA. Translation: AAP68210.1.
AY087686 mRNA. Translation: AAM65223.1.
PIRiT13450.
RefSeqiNP_567693.1. NM_118538.4. [Q8LAP8-1]
UniGeneiAt.3662.

Genome annotation databases

EnsemblPlantsiAT4G24060.1; AT4G24060.1; AT4G24060. [Q8LAP8-1]
GeneIDi828506.
GrameneiAT4G24060.1; AT4G24060.1; AT4G24060.
KEGGiath:AT4G24060.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiDOF46_ARATH
AccessioniPrimary (citable) accession number: Q8LAP8
Secondary accession number(s): O22984, Q94C22, Q9SU49
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: November 9, 2004
Last modified: September 27, 2017
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names