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Protein

Probable aquaporin NIP7-1

Gene

NIP7-1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.By similarity

GO - Molecular functioni

  • active borate transmembrane transporter activity Source: TAIR
  • water channel activity Source: GO_Central

GO - Biological processi

  • borate transmembrane transport Source: TAIR

Keywordsi

Biological processTransport

Protein family/group databases

TCDBi1.A.8.12.6 the major intrinsic protein (mip) family

Names & Taxonomyi

Protein namesi
Recommended name:
Probable aquaporin NIP7-1
Alternative name(s):
NOD26-like intrinsic protein 7-1
Short name:
AtNIP7;1
Gene namesi
Name:NIP7-1
Ordered Locus Names:At3g06100
ORF Names:F28L1.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G06100
TAIRilocus:2082385 AT3G06100

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei47 – 67Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei76 – 96Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei127 – 147Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei161 – 181Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei192 – 212Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei231 – 251Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000640701 – 275Probable aquaporin NIP7-1Add BLAST275

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei272PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8LAI1

Expressioni

Tissue specificityi

Expressed in floral buds.1 Publication

Gene expression databases

ExpressionAtlasiQ8LAI1 baseline and differential
GenevisibleiQ8LAI1 AT

Interactioni

Protein-protein interaction databases

BioGridi5118, 12 interactors
IntActiQ8LAI1, 5 interactors
STRINGi3702.AT3G06100.1

Structurei

3D structure databases

ProteinModelPortaliQ8LAI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi105 – 107NPA 13
Motifi217 – 219NPA 23

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala/Ser (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0223 Eukaryota
COG0580 LUCA
HOGENOMiHOG000288286
InParanoidiQ8LAI1
KOiK09874
OMAiCGPHQNL
OrthoDBiEOG09360IF1
PhylomeDBiQ8LAI1

Family and domain databases

CDDicd00333 MIP, 1 hit
Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR034294 Aquaporin_transptr
IPR000425 MIP
IPR022357 MIP_CS
PANTHERiPTHR19139 PTHR19139, 1 hit
PfamiView protein in Pfam
PF00230 MIP, 1 hit
PRINTSiPR00783 MINTRINSICP
SUPFAMiSSF81338 SSF81338, 1 hit
PROSITEiView protein in PROSITE
PS00221 MIP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8LAI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGEARSRVV DQEAGSTPST LRDEDHPSRQ RLFGCLPYDI DLNPLRIVMA
60 70 80 90 100
ELVGTFILMF SVCGVISSTQ LSGGHVGLLE YAVTAGLSVV VVVYSIGHIS
110 120 130 140 150
GAHLNPSITI AFAVFGGFPW SQVPLYITAQ TLGATAATLV GVSVYGVNAD
160 170 180 190 200
IMATKPALSC VSAFFVELIA TSIVVFLASA LHCGPHQNLG NLTGFVIGTV
210 220 230 240 250
ISLGVLITGP ISGGSMNPAR SLGPAVVAWD FEDLWIYMTA PVIGAIIGVL
260 270
TYRSISLKTR PCPSPVSPSV SSLLR
Length:275
Mass (Da):28,746
Last modified:April 12, 2005 - v2
Checksum:i74DEE285C4A755EF
GO

Sequence cautioni

The sequence AAF30303 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence ABK28544 differs from that shown. Reason: Erroneous termination at position 276. Translated as stop.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti273L → F in AAM65333 (PubMed:17147637).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018907 Genomic DNA Translation: AAF30303.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE74343.1
DQ446638 mRNA Translation: ABE65919.1
DQ653067 mRNA Translation: ABK28544.1 Sequence problems.
AY087797 mRNA Translation: AAM65333.1
RefSeqiNP_566271.1, NM_111485.3
UniGeneiAt.40569

Genome annotation databases

EnsemblPlantsiAT3G06100.1; AT3G06100.1; AT3G06100
GeneIDi819783
GrameneiAT3G06100.1; AT3G06100.1; AT3G06100
KEGGiath:AT3G06100

Similar proteinsi

Entry informationi

Entry nameiNIP71_ARATH
AccessioniPrimary (citable) accession number: Q8LAI1
Secondary accession number(s): A0MEU4, Q1PES9, Q9M8K8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: April 12, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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