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Protein

Probable aquaporin NIP7-1

Gene

NIP7-1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.By similarity

GO - Molecular functioni

GO - Biological processi

  • borate transmembrane transport Source: TAIR
  • cellular water homeostasis Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Transport

Protein family/group databases

TCDBi1.A.8.12.6. the major intrinsic protein (mip) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable aquaporin NIP7-1
Alternative name(s):
NOD26-like intrinsic protein 7-1
Short name:
AtNIP7;1
Gene namesi
Name:NIP7-1
Ordered Locus Names:At3g06100
ORF Names:F28L1.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G06100.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei47 – 6721Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei76 – 9621Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei127 – 14721Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei161 – 18121Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei192 – 21221Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei231 – 25121Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 275275Probable aquaporin NIP7-1PRO_0000064070Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei272 – 2721PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8LAI1.

Expressioni

Tissue specificityi

Expressed in floral buds.1 Publication

Gene expression databases

GenevisibleiQ8LAI1. AT.

Interactioni

Protein-protein interaction databases

BioGridi5118. 12 interactions.
STRINGi3702.AT3G06100.1.

Structurei

3D structure databases

ProteinModelPortaliQ8LAI1.
SMRiQ8LAI1. Positions 46-255.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi105 – 1073NPA 1
Motifi217 – 2193NPA 2

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala/Ser (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0223. Eukaryota.
COG0580. LUCA.
HOGENOMiHOG000288286.
InParanoidiQ8LAI1.
KOiK09874.
OMAiHVGLLEY.
OrthoDBiEOG09360IF1.
PhylomeDBiQ8LAI1.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8LAI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGEARSRVV DQEAGSTPST LRDEDHPSRQ RLFGCLPYDI DLNPLRIVMA
60 70 80 90 100
ELVGTFILMF SVCGVISSTQ LSGGHVGLLE YAVTAGLSVV VVVYSIGHIS
110 120 130 140 150
GAHLNPSITI AFAVFGGFPW SQVPLYITAQ TLGATAATLV GVSVYGVNAD
160 170 180 190 200
IMATKPALSC VSAFFVELIA TSIVVFLASA LHCGPHQNLG NLTGFVIGTV
210 220 230 240 250
ISLGVLITGP ISGGSMNPAR SLGPAVVAWD FEDLWIYMTA PVIGAIIGVL
260 270
TYRSISLKTR PCPSPVSPSV SSLLR
Length:275
Mass (Da):28,746
Last modified:April 12, 2005 - v2
Checksum:i74DEE285C4A755EF
GO

Sequence cautioni

The sequence AAF30303 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence ABK28544 differs from that shown. Reason: Erroneous termination at position 276. Translated as stop.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti273 – 2731L → F in AAM65333 (PubMed:17147637).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018907 Genomic DNA. Translation: AAF30303.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE74343.1.
DQ446638 mRNA. Translation: ABE65919.1.
DQ653067 mRNA. Translation: ABK28544.1. Sequence problems.
AY087797 mRNA. Translation: AAM65333.1.
RefSeqiNP_566271.1. NM_111485.2.
UniGeneiAt.40569.

Genome annotation databases

EnsemblPlantsiAT3G06100.1; AT3G06100.1; AT3G06100.
GeneIDi819783.
GrameneiAT3G06100.1; AT3G06100.1; AT3G06100.
KEGGiath:AT3G06100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018907 Genomic DNA. Translation: AAF30303.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE74343.1.
DQ446638 mRNA. Translation: ABE65919.1.
DQ653067 mRNA. Translation: ABK28544.1. Sequence problems.
AY087797 mRNA. Translation: AAM65333.1.
RefSeqiNP_566271.1. NM_111485.2.
UniGeneiAt.40569.

3D structure databases

ProteinModelPortaliQ8LAI1.
SMRiQ8LAI1. Positions 46-255.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi5118. 12 interactions.
STRINGi3702.AT3G06100.1.

Protein family/group databases

TCDBi1.A.8.12.6. the major intrinsic protein (mip) family.

Proteomic databases

PaxDbiQ8LAI1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G06100.1; AT3G06100.1; AT3G06100.
GeneIDi819783.
GrameneiAT3G06100.1; AT3G06100.1; AT3G06100.
KEGGiath:AT3G06100.

Organism-specific databases

TAIRiAT3G06100.

Phylogenomic databases

eggNOGiKOG0223. Eukaryota.
COG0580. LUCA.
HOGENOMiHOG000288286.
InParanoidiQ8LAI1.
KOiK09874.
OMAiHVGLLEY.
OrthoDBiEOG09360IF1.
PhylomeDBiQ8LAI1.

Miscellaneous databases

PROiQ8LAI1.

Gene expression databases

GenevisibleiQ8LAI1. AT.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNIP71_ARATH
AccessioniPrimary (citable) accession number: Q8LAI1
Secondary accession number(s): A0MEU4, Q1PES9, Q9M8K8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: April 12, 2005
Last modified: September 7, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.