ID   Q8L9W4_ARATH            Unreviewed;       593 AA.
AC   Q8L9W4;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 124.
DE   SubName: Full=Non-expressor of PR1 {ECO:0000313|EMBL:ABR46025.1};
DE   SubName: Full=Regulatory protein NPR1 (Nonexpresser of PR genes 1) (Noninducible immunity 1) (Nim1) (Salicylic acid insensitive 1) (Sai1) {ECO:0000313|EMBL:AAM65726.1};
GN   Name=NPR1 {ECO:0000313|EMBL:ABR46025.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:AAM65726.1};
RN   [1] {ECO:0000313|EMBL:AAM65726.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12093376;
RA   Haas B.J., Volfovsky N., Town C.D., Troukhan M., Alexandrov N.,
RA   Feldmann K.A., Flavell R.B., White O., Salzberg S.L.;
RT   "Full-length messenger RNA sequences greatly improve genome annotation.";
RL   Genome Biol. 3:RESEARCH0029-RESEARCH0029(2002).
RN   [2] {ECO:0000313|EMBL:AAM65726.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Brover V., Troukhan M., Alexandrov N., Lu Y.-P., Flavell R., Feldmann K.;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAM65726.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Alexandrov N.A., Troukhan M.E., Brover V.V., Flavell R.B., Feldmann K.A.;
RT   "Features of Arabidopsis genes and genome discovered using full-length
RT   cDNAs.";
RL   Plant Mol. Biol. 60:71-87(2006).
RN   [4] {ECO:0000313|EMBL:ABR46025.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=19064707; DOI=10.1534/genetics.108.097279;
RA   Caldwell K.S., Michelmore R.W.;
RT   "Arabidopsis thaliana genes encoding defense signaling and recognition
RT   proteins exhibit contrasting evolutionary dynamics.";
RL   Genetics 181:671-684(2009).
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- INTERACTION:
CC       Q8L9W4; Q9FNZ5: NIMIN-1; NbExp=5; IntAct=EBI-541093, EBI-541099;
CC       Q8L9W4; Q9LUA3: NIMIN-2; NbExp=5; IntAct=EBI-541093, EBI-541107;
CC       Q8L9W4; Q9FNZ4: NIMIN-3; NbExp=3; IntAct=EBI-541093, EBI-541115;
CC       Q8L9W4; P43273: TGA2; NbExp=7; IntAct=EBI-541093, EBI-541307;
CC       Q8L9W4; Q39163: TGA5; NbExp=4; IntAct=EBI-541093, EBI-541381;
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DR   EMBL; AY088183; AAM65726.1; -; mRNA.
DR   EMBL; EF470720; ABR46025.1; -; Genomic_DNA.
DR   EMBL; EF470721; ABR46026.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8L9W4; -.
DR   IntAct; Q8L9W4; 10.
DR   UniPathway; UPA00143; -.
DR   ExpressionAtlas; Q8L9W4; baseline and differential.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:2000022; P:regulation of jasmonic acid mediated signaling pathway; IEA:InterPro.
DR   GO; GO:2000031; P:regulation of salicylic acid mediated signaling pathway; IEA:InterPro.
DR   GO; GO:0009862; P:systemic acquired resistance, salicylic acid mediated signaling pathway; IEA:InterPro.
DR   CDD; cd18310; BTB_POZ_NPR_plant; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR044292; NPR.
DR   InterPro; IPR021094; NPR1/NIM1-like_C.
DR   InterPro; IPR024228; NPR_central_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR46475:SF11; REGULATORY PROTEIN NPR1; 1.
DR   PANTHER; PTHR46475; REGULATORY PROTEIN NPR3; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF11900; DUF3420; 1.
DR   Pfam; PF12313; NPR1_like_C; 1.
DR   SMART; SM00248; ANK; 2.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   1: Evidence at protein level;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}.
FT   DOMAIN          65..144
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REPEAT          328..360
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          563..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        563..582
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  66049 MW;  A97B8448176E35E8 CRC64;
     MDTTIDGFAD SYEISSTSFV ATDNTDSSIV YLAAEQVLTG PDVSALQLLS NSFESVFDSP
     DDFYSDAKLV LSDGREVSFH RCVLSARSSF FKSALAAAKK EKDSNNTAAV KLELKEIAKD
     YEVGFDSVVT VLAYVYSSRV RPPPKGVSEC ADENCCHVAC RPAVDFMLEV LYLAFIFRIP
     ELVTLYQRHL LDVVDKVVIE DTLVILKLAN ICGKACMKLL DRCKEIIVKS NVDMVSLEKS
     LPEELVKEII DRRKELGLEV PKVKKHVSNV HKALDSDDIE LVKLLLKEDH TNLDDACALH
     FAVAYCNVKT ATDLLKLDLA DVNHRNPRGY TVLHVAAMRK EPQLILSLLE KGASASEATL
     EGRTALMIAK QATMAVECNN IPEQCKHSLK GRLCVEILEQ EDKREPIPRD VPPSFAVAAD
     ELKMTLLDLE NRVALAQRLF PTEAQAAMEI AEMKGTCEFI VTSLEPDRLT GTKRTSPGVK
     IAPFRILEEH QSRLKALSKT VELGKRFFPR CSAVLDQIMN CEDLTQLACG EDDTAEKRLQ
     KKQRYMEIQE TLKKAFSEDN LELGNSSLTD STSSTSKSTG GKRSNRKFSH RRR
//